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View Structure Prediction Details

Protein: GYP5
Organism: Saccharomyces cerevisiae
Length: 894 amino acids
Reference: Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for GYP5.

Description E-value Query
Range
Subject
Range
gi|114593160 - gi|114593160|ref|XP_526514.2| PREDICTED: TBC1 domain family, member 14 [Pan troglodytes]
443.0 [0..1] [707..124]

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Predicted Domain #1
Region A:
Residues: [1-412]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MSSDKSIEKN TDTIASEVHE GDNHSNNLGS MEEEIKSTPS DQYEEIAIIP TEPLHSDKEL  60
   61 NDKQQSLGHE APTNVSREEP IGISGDEDTQ ITEQNVNEQR QETREPSSEI DLNEPLDVEK 120
  121 DVTTDVQAPN GLNIEKEYDA VKENEKVYAD TKEVVSSPEN REVTGKNSGG EKSSSSKFLD 180
  181 DESGTTTAAN ANDISISSEV TPERSSENDN NQIHITNEVA AGINLNENKE QKAAIEDGPV 240
  241 TAENLSSETA RKVPPIPTQI INEKGDNSSE NEVSAIPTTS SPPLPPRQNV ATSTSPKLPP 300
  301 RGKQREQPPK TKNAVPPPLE EEMKSEKFRK NFEETKRNSY HHVPLTGSKT AQLESTAEIN 360
  361 LIASRYRKTS HHLNKEGEET RESLQEGQSF LKSTFTSFLE NLSEYNEVEN VN

[Run NCBI BLAST on this sequence.]

Detection Method: MSA

Shown below are all of our structure predictions for this domain.
Click here to view only most confident match.

Found no structure predictions for this domain.

Predicted Domain #2
Region A:
Residues: [413-637]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 EEDREMFKID WSFWTQVVND YATVASNEPE NLEAHVTNGI PPQIRGIIWQ LMANSKSREM  60
   61 EDIYETLLDT ECLHEATIRR DLRRTKFVAE DKMESLYKVI KVYSVYDPDV GYTQGMGFIA 120
  121 APLLINCENE AESFGLLVGL MKNYGLRELF LPGMPGLMLM LYQFDRLLEE HSPSLYNRLI 180
  181 REGISSTMYA TQWFLTFFAY KFPLEFVLRI FDIVFVEGIE VLLKF

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 36.221849
Match: 1fkmA_
Description: Ypt/Rab-GAP domain of gyp1p
Matching Structure (courtesy of the PDB):

Predicted Domain #3
Region A:
Residues: [638-813]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 AVNLMLKNEE TLVKLRFDEL LDFLKDELFN YYLMGNQDDA SVVQMGLSNG NSFKGNDDGT  60
   61 FSYNVDLFVH DAMTGVYITP LTLRRYRGEY VEIHEKEQKK EDHYESLRIQ NHQLQREAQK 120
  121 LEHDYSILNK ENISAANELI QNRLNMEMLL DEKNDLINTI TDIKSQIEEE IRKQNL

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 22.69897
Match: 1i84S_
Description: Heavy meromyosin subfragment
Matching Structure (courtesy of the PDB):

Predicted Domain #4
Region A:
Residues: [814-894]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 PNPDASLPKA DLREDLERTI SRNNEVMREN GQLEERITEL QAEIDELINI NKEQVSTASL  60
   61 LERDSKAKGR KGWTGFKKVF K

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below are all of our de novo (Rosetta) predictions for this domain.
Click here to view only most confident match.

    MCM
Score
SCOP
Match
SCOP Description
View Download 0.579 a.4.5 "Winged helix" DNA-binding domain
View Download 0.631 a.52.1 Bifunctional inhibitor/lipid-transfer protein/seed storage 2S albumin
View Download 0.651 a.101.1 Uteroglobin-like
View Download 0.664 f.15.1 Small-conductance potassium channel
View Download 0.564 a.181.1 Antibiotic binding domain of TipA-like multidrug resistance regulators
View Download 0.551 a.27.1 Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases
View Download 0.550 a.51.1 Cytochrome c oxidase subunit h
View Download 0.497 a.8.3 Families 57/38 glycoside transferase middle domain
View Download 0.480 a.24.17 Group V grass pollen allergen
View Download 0.467 a.4.5 "Winged helix" DNA-binding domain
View Download 0.462 a.64.1 Saposin
View Download 0.448 a.24.7 FKBP12-rapamycin-binding domain of FKBP-rapamycin-associated protein (FRAP)
View Download 0.436 a.8.2 Plasmid maintenance system epsilon/zeta, antidote epsilon subunit
View Download 0.432 a.60.9 lambda integrase-like, N-terminal domain
View Download 0.418 d.8.1 Urease, gamma-subunit
View Download 0.417 a.12.1 Kix domain of CBP (creb binding protein)
View Download 0.408 a.1.1 Globin-like
View Download 0.407 a.71.1 Endoplasmic reticulum protein ERP29, C-domain
View Download 0.403 a.112.1 Description not found.
View Download 0.403 a.2.7 tRNA-binding arm
View Download 0.382 a.48.3 Conserved domain common to transcription factors TFIIS, elongin A, CRSP70
View Download 0.380 a.4.1 Homeodomain-like
View Download 0.378 a.29.4 RecG, N-terminal domain
View Download 0.377 d.188.1 Prokaryotic ribosomal protein L17
View Download 0.361 a.126.1 Serum albumin-like
View Download 0.345 a.24.3 Cytochromes
View Download 0.327 a.2.3 Chaperone J-domain
View Download 0.309 a.46.1 Methionine synthase domain
View Download 0.306 a.39.1 EF-hand
View Download 0.300 a.80.1 DNA polymerase III clamp loader subunits, C-terminal domain
View Download 0.291 a.24.11 Bacterial GAP domain
View Download 0.281 a.23.4 Mitochondrial import receptor subunit Tom20
View Download 0.274 a.118.8 TPR-like
View Download 0.274 a.157.1 Skp1 dimerisation domain-like
View Download 0.273 d.15.2 CAD & PB1 domains
View Download 0.270 f.36.1 Neurotransmitter-gated ion-channel pransmembrane pore
View Download 0.269 a.7.6 Ribosomal protein S20
View Download 0.266 d.26.1 FKBP-like
View Download 0.266 a.7.7 BAG domain
View Download 0.265 a.4.5 "Winged helix" DNA-binding domain
View Download 0.264 a.2.8 Eukaryotic DNA topoisomerase I, dispensable insert domain
View Download 0.258 a.57.1 Protein HNS-dependent expression A; HdeA
View Download 0.252 a.156.1 S13-like H2TH domain
View Download 0.252 a.85.1 Hemocyanin, N-terminal domain
View Download 0.249 a.39.1 EF-hand
View Download 0.248 a.39.1 EF-hand
View Download 0.248 a.39.1 EF-hand
View Download 0.245 a.156.1 S13-like H2TH domain
View Download 0.245 a.71.2 Helical domain of Sec23/24
View Download 0.234 a.17.1 p8-MTCP1
View Download 0.222 a.76.1 Iron-dependent represor protein, dimerization domain
View Download 0.222 a.4.12 TrpR-like
View Download 0.216 a.4.1 Homeodomain-like
View Download 0.215 a.1.1 Globin-like
View Download 0.215 a.1.1 Globin-like
View Download 0.212 d.55.1 Ribosomal protein L22
View Download 0.208 a.1.1 Globin-like
View Download 0.208 a.77.1 DEATH domain
View Download 0.206 a.4.6 C-terminal effector domain of the bipartite response regulators
View Download 0.202 a.8.3 Families 57/38 glycoside transferase middle domain
View Download 0.202 a.35.1 lambda repressor-like DNA-binding domains
View Download 0.201 a.4.9 Polynucleotide phosphorylase/guanosine pentaphosphate synthase (PNPase/GPSI), domain 3
View Download 0.201 c.30.1 PreATP-grasp domain


YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle