YRC Public Data Repository - Protein Structure Prediction

Protein:	ALG5
Organism:	Saccharomyces cerevisiae
Length:	334 amino acids
Reference:	Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for ALG5.

Description	E-value	Query Range	Subject Range
ALG5_YEAST - Dolichyl-phosphate beta-glucosyltransferase OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c)... ALG5 - UDP-glucose:dolichyl-phosphate glucosyltransferase, involved in asparagine-linked glycosylation in t...	6.0E-67	[1..334]	[1..334]
alg5 - dolichyl-phosphate beta-glucosyltransferase Alg5 ALG5_SCHPO - Dolichyl-phosphate beta-glucosyltransferase OS=Schizosaccharomyces pombe (strain 972 / ATCC 24843) G...	1.0E-54	[13..328]	[5..313]
gi\|148229286, gi... - gi\|28277330\|gb\|AAH44127.1\| Alg5 protein [Xenopus laevis], gi\|148229286\|ref\|NP_001080634.1\| dolichyl-...	3.0E-54	[17..330]	[10..317]
ALG5_MOUSE - Dolichyl-phosphate beta-glucosyltransferase OS=Mus musculus GN=Alg5 PE=1 SV=1	7.0E-54	[7..332]	[3..319]
gi\|2984166, gi\|1... - gi\|2984166\|gb\|AAC07699.1\| dolichol-phosphate mannosyltransferase [Aquifex aeolicus VF5], gi\|15606924... gi\|7446791 - pir\|\|G70463 dolichol-phosphate mannosyltransferase - Aquifex aeolicus	3.0E-53	[75..321]	[2..221]
gi\|85106656 - gi\|85106656\|ref\|XP_962224.1\| hypothetical protein NCU06386 [Neurospora crassa OR74A] gi\|32411521, gi\|... - gi\|32411521\|ref\|XP_326241.1\| hypothetical protein [Neurospora crassa], gi\|28923824\|gb\|EAA32988.1\| hy...	4.0E-53	[3..331]	[25..437]
wol-PA - The gene wollknaeuel is referred to in FlyBase by the symbol Dmel\wol (CG7870, FBgn0261020). It is a... gi\|220954018, gi... - gi\|220954018\|gb\|ACL89552.1\| CG7870-PA [synthetic construct], gi\|220944034\|gb\|ACL84560.1\| CG7870-PA [...	6.0E-53	[11..330]	[5..318]
gi\|9963765 - gi\|9963765\|gb\|AAG09682.1\|AF183413_1 dolichyl-phosphate beta-glucosyltransferase [Homo sapiens]	2.0E-52	[11..330]	[4..317]
gi\|32474179, gi\|... - gi\|32474179\|ref\|NP_867173.1\| dolichol-phosphate mannosyltransferase [Rhodopirellula baltica SH 1], g...	3.0E-52	[57..331]	[52..302]

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Predicted Domain #1

Region A:
Residues: [1-67]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MRALRFLIEN RNTVFFTLLV ALVLSLYLLV YLFSHTPRPP YPEELKYIAI DEKGHEVSRA  60
   61 LPNLNEH

[Run NCBI BLAST on this sequence.]

Detection Method:

deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #2

Region A:
Residues: [68-217]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 QDDEEIFLSV VIPSYNETGR ILLMLTDAIS FLKEKYGSRW EIVIVDDGST DNTTQYCLKI  60
   61 CKEQFKLNYE QFRIIKFSQN RGKGGAVRQG FLHIRGKYGL FADADGASKF SDVEKLIDAI 120
  121 SKIETSSTDL KTTKPAVAIG SRAHMVNTEA

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	10.69897
Match:	1h7lA_
Description:	Spore coat polysaccharide biosynthesis protein SpsA
Matching Structure (courtesy of the PDB):

Predicted Domain #3

Region A:
Residues: [218-334]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 VIKRSMIRNC LMYGFHTLVF IFGIRSIKDT QCGFKLFNRA AILKIFPYLH TEGWIFDVEI  60
   61 LILAIRKRIQ IEEIPISWHE VDGSKMALAI DSIKMAKDLV IIRMAYLLGI YRDNKKC

[Run NCBI BLAST on this sequence.]

Detection Method:

MSA

Shown below is our most confident prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits