YRC Public Data Repository - Protein Structure Prediction

Protein:	COX10
Organism:	Saccharomyces cerevisiae
Length:	462 amino acids
Reference:	Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076

[What does the above image mean?]

[Show Ginzu Version Information]

Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for COX10.

Description	E-value	Query Range	Subject Range
COX10_YEAST - Protoheme IX farnesyltransferase, mitochondrial OS=Saccharomyces cerevisiae (strain ATCC 204508 / S2... COX10 - Heme A:farnesyltransferase, catalyzes the first step in the conversion of protoheme to the heme A pr... gi\|207340665 - gi\|207340665\|gb\|EDZ68947.1\| YPL172Cp-like protein [Saccharomyces cerevisiae AWRI1631]	0.0	[1..462]	[1..462]
COX10 - COX10 homolog, cytochrome c oxidase assembly protein, heme A: farnesyltransferase (yeast) gi\|60656253, gi\|... - gi\|60656255\|gb\|AAX32691.1\| COX10-like [synthetic construct], gi\|60656253\|gb\|AAX32690.1\| COX10-like [...	4.0E-65	[1..405]	[29..413]
gi\|60653195, gi\|... - gi\|60653197\|gb\|AAX29293.1\| cytochrome c oxidase assembly protein [synthetic construct], gi\|60653195\|...	5.0E-65	[1..405]	[29..413]
gi\|7507776 - gi\|7507776\|pir\|\|T16867 probable cytochrome P450 T13C5.1 [similarity] - Caenorhabditis elegans	1.0E-64	[1..405]	[29..413]
Coq2-PA - The gene Coenzyme Q biosynthesis protein 2 is referred to in FlyBase by the symbol Dmel\Coq2 (CG9613... gi\|220949886 - gi\|220949886\|gb\|ACL87486.1\| Coq2-PA [synthetic construct]	1.0E-54	[85..424]	[3..359]
UBIA_VIBPA - 4-hydroxybenzoate octaprenyltransferase OS=Vibrio parahaemolyticus serotype O3:K6 (strain RIMD 22106... UBIA_VIBPA - 4-hydroxybenzoate octaprenyltransferase OS=Vibrio parahaemolyticus GN=ubiA PE=3 SV=1 gi\|153839844, gi... - gi\|153839844\|ref\|ZP_01992511.1\| 4-hydroxybenzoate polyprenyl transferase [Vibrio parahaemolyticus AQ...	7.0E-53	[141..423]	[1..284]
gi\|7480566 - pir\|\|T36006 probable cytochrome oxidase assembly factor - Streptomyces coelicolor gi\|5459401, gi\|2... - gi\|5459401\|emb\|CAB50759.1\| putative cytochrome oxidase assembly factor [Streptomyces coelicolor A3(2...	4.0E-52	[122..444]	[27..338]

Back

Predicted Domain #1

Region A:
Residues: [1-83]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MSYFPRTYAH LMRNVLAHNK GNIYLQIGTQ LHDTQIKIRF NGVRYISRNH GGKQQHINTA  60
   61 PIEFTPNFGY GDRTSNCNKK VES

[Run NCBI BLAST on this sequence.]

Detection Method:

MSA

Shown below is our most confident prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #2

Region A:
Residues: [84-154]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 TAMKTLRCTD DISTSSGSEA TTDASTQLPF NVKLVDPMVR KSKRPSHAIS EGLNMKTLKK  60
   61 KVIMPYLQLT K

[Run NCBI BLAST on this sequence.]

Detection Method:

deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

		MCM Score	GO Score	GO Term	SCOP Match	SCOP Description
View	Download	0.298	0.849	mitochondrial inner membrane	a.3.1	Cytochrome c

Predicted Domain #3

Region A:
Residues: [155-462]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 PRLTILVMLS AICSYALSPY PASVNELLCL TVGTTLCSGS ANAINMGREP EFDRQMVRTQ  60
   61 ARPVVRGDVT PTQAFEFAAL IGTLGVSILY FGVNPTVAIL GASNIALYGW AYTSMKRKHI 120
  121 INTWLGALVG MVPPLMGWAA ASPLSHPGSW CLAGLLFAWQ FPHFNTLSHN IRNEYKNAGY 180
  181 VMTAWKNPLL NARVSLRYSI LMFPLCFGLS YFNITDWYYQ IDSGLINAWL TFWAFKFYWQ 240
  241 QRINYSAKTL KDNVKFNKGL SVANIYARKT FMASVLHLPA ILILAIIHKK GRWDWIYPGE 300
  301 AKRPQERF

[Run NCBI BLAST on this sequence.]

Detection Method:	Pfam
Confidence:	71.568636
Match:	PF01040
Description:	UbiA prenyltransferase family

Shown below is our most confident prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits