YRC Public Data Repository - Protein Structure Prediction

Protein:	PRM4
Organism:	Saccharomyces cerevisiae
Length:	284 amino acids
Reference:	Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for PRM4.

Description	E-value	Query Range	Subject Range
PRM4 - Pheromone-regulated protein proposed to be involved in mating; predicted to have 1 transmembrane seg... PRM4_YEAST - Pheromone-regulated membrane protein 4 OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=P...	3.0E-67	[1..284]	[1..284]
GRS17_ARATH - Monothiol glutaredoxin-S17 OS=Arabidopsis thaliana GN=GRXS17 PE=1 SV=1	9.0E-35	[50..269]	[53..253]
GRS11_ORYSJ - Monothiol glutaredoxin-S11 OS=Oryza sativa subsp. japonica GN=GRXS11 PE=2 SV=2 GRS11_ORYSA - Monothiol glutaredoxin-S11 - Oryza sativa (Rice)	2.0E-34	[48..267]	[50..248]
grx4 - glutaredoxin Grx4 GLRX4_SCHPO - Monothiol glutaredoxin-4 OS=Schizosaccharomyces pombe (strain 972 / ATCC 24843) GN=grx4 PE=1 SV=1	1.0E-32	[47..265]	[49..242]
gi\|85117048 - gi\|85117048\|ref\|XP_965167.1\| hypothetical protein NCU00974 [Neurospora crassa OR74A] gi\|32409347, gi\|... - gi\|38567046\|emb\|CAE76344.1\| related to glutaredoxin [Neurospora crassa], gi\|32409347\|ref\|XP_325154.1...	2.0E-31	[55..280]	[37..252]
gi\|4929735 - gi\|4929735\|gb\|AAD34128.1\|AF151891_1 CGI-133 protein [Homo sapiens]	4.0E-30	[110..277]	[4..149]
gi\|2724050, gi\|2... - gi\|2724056\|gb\|AAB92658.1\| glutaredoxin type I [Fritillaria agrestis], gi\|2724054\|gb\|AAB92657.1\| glut...	1.0E-28	[158..272]	[4..103]
gi\|116310771, gi... - gi\|125548975\|gb\|EAY94797.1\| hypothetical protein OsI_16580 [Oryza sativa Indica Group], gi\|116310771... GRXC6_ORYSA, GLR... - Glutaredoxin-C6 (Glutaredoxin-C2 homolog 1) - Oryza sativa (Rice), (P55142) Glutaredoxin GRXC6_ORYSJ - Glutaredoxin-C6 OS=Oryza sativa subsp. japonica GN=GRXC6 PE=1 SV=2	6.0E-28	[158..276]	[4..107]

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Predicted Domain #1

Region A:
Residues: [1-118]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MIADSSVLKK HTAIKRSTRI ISLTLVLLGV FSFLLLTWND SLEFYNSADP SENKKNSEEE  60
   61 SEKKFVYKLP NLLKTADSFL SNENELNFQK VKEEISNIQS EVEVDIPEPS SKATSKFS

[Run NCBI BLAST on this sequence.]

Detection Method:

deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #2

Region A:
Residues: [119-284]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 SRSFQTDNVV TATTTTTLNP RSSSLALQKN CDHKKFDPRT DFLDIIRTSP AVLFIKSSQA  60
   61 DSIFLKNLLQ REFEISPELA TVDLEKHSHG YELEKYIKQN KLNIDTSAAL ESIQSPYLFL 120
  121 NGISVINRGM VRDIIEPHSK GLLLPLLKSE ARGNLLVEKK DIPSNS

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	25.154902
Match:	1jhb__
Description:	Glutaredoxin (Grx, thioltransferase)
Matching Structure (courtesy of the PDB):

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits