YRC Public Data Repository - Protein Structure Prediction

Protein:	KIP2
Organism:	Saccharomyces cerevisiae
Length:	706 amino acids
Reference:	Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for KIP2.

Description	E-value	Query Range	Subject Range
KIP2_YEAST - Kinesin-like protein KIP2 OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=KIP2 PE=1 SV=1 KIP2 - Kinesin-related motor protein involved in mitotic spindle positioning, stabilizes microtubules by ta... gi\|151942644 - gi\|151942644\|gb\|EDN60990.1\| kinesin-related protein [Saccharomyces cerevisiae YJM789]	0.0	[1..706]	[1..706]
gi\|29421214 - gi\|29421214\|dbj\|BAA31614.3\| KIAA0639 protein [Homo sapiens]	0.0	[100..633]	[12..491]
gi\|13235654, gi\|... - gi\|148228464\|ref\|NP_001084268.1\| minesin-like protein [Xenopus laevis], gi\|13235654\|emb\|CAC33801.1\| ...	0.0	[92..705]	[4..570]
gi\|4512330 - gi\|4512330\|dbj\|BAA75243.1\| KIF1B-beta [Mus musculus]	0.0	[99..641]	[2..472]
gi\|8248421 - gi\|8248421\|gb\|AAF74192.1\|AF247761_1 kinesin superfamily member DUnc104 [Drosophila melanogaster]	0.0	[101..599]	[2..450]
gi\|32413078, gi\|... - gi\|32413078\|ref\|XP_327019.1\| hypothetical protein [Neurospora crassa], gi\|28922174\|gb\|EAA31425.1\| hy... gi\|85098745 - gi\|85098745\|ref\|XP_960661.1\| hypothetical protein [Neurospora crassa OR74A]	0.0	[100..616]	[11..483]
KRP85_STRPU - Kinesin-II 85 kDa subunit OS=Strongylocentrotus purpuratus GN=KRP85 PE=1 SV=1	0.0	[102..705]	[10..568]

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Predicted Domain #1

Region A:
Residues: [1-71]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MIQKMSPSLR RPSTRSSSGS SNIPQSPSVR STSSFSNLTR NSIRSTSNSG SQSISASSTR  60
   61 SNSPLRSVSA K

[Run NCBI BLAST on this sequence.]

Detection Method:

deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #2

Region A:
Residues: [72-507]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 SDPFLHPGRI RIRRSDSINN NSRKNDTYTG SITVTIRPKP RSVGTSRDHV GLKSPRYSQP  60
   61 RSNSHHGSNT FVRDPWFITN DKTIVHEEIG EFKFDHVFAS HCTNLEVYER TSKPMIDKLL 120
  121 MGFNATIFAY GMTGSGKTFT MSGNEQELGL IPLSVSYLFT NIMEQSMNGD KKFDVIISYL 180
  181 EIYNERIYDL LESGLEESGS RISTPSRLYM SKSNSNGLGV ELKIRDDSQY GVKVIGLTER 240
  241 RCESSEELLR WIAVGDKSRK IGETDYNARS SRSHAIVLIR LTSTNVKNGT SRSSTLSLCD 300
  301 LAGSERATGQ QERRKEGSFI NKSLLALGTV ISKLSADKMN SVGSNIPSPS ASGSSSSSGN 360
  361 ATNNGTSPSN HIPYRDSKLT RLLQPALSGD SIVTTICTVD TRNDAAAETM NTLRFASRAK 420
  421 NVALHVSKKS IISNGN

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	562.228787
Match:	1gojA_
Description:	Kinesin
Matching Structure (courtesy of the PDB):

Predicted Domain #3

Region A:
Residues: [508-706]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 NDGDKDRTIE LLRRQLEEQR RMISELKNRS NIGEPLTKSS NESTYKDIKA TGNDGDPNLA  60
   61 LMRAENRVLK YKLENCEKLL DKDVVDLQDS EIMEIVEMLP FEVGTLLETK FQGLESQIRQ 120
  121 YRKYTQKLED KIMALEKSGH TAMSLTGCDG TEVIELQKML ERKDKMIEAL QSAKRLRDRA 180
  181 LKPLINTQQS PHPVVDNDK

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	11.69897
Match:	1i84S_
Description:	Heavy meromyosin subfragment
Matching Structure (courtesy of the PDB):

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits