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View Structure Prediction Details

Protein: KIP2
Organism: Saccharomyces cerevisiae
Length: 706 amino acids
Reference: Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for KIP2.

Description E-value Query
Range
Subject
Range
KIP2_YEAST - Kinesin-like protein KIP2 OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=KIP2 PE=1 SV=1
KIP2 - Kinesin-related motor protein involved in mitotic spindle positioning, stabilizes microtubules by ta...
gi|151942644 - gi|151942644|gb|EDN60990.1| kinesin-related protein [Saccharomyces cerevisiae YJM789]
0.0 [1..706] [1..706]
gi|29421214 - gi|29421214|dbj|BAA31614.3| KIAA0639 protein [Homo sapiens]
0.0 [100..633] [12..491]
gi|13235654, gi|... - gi|148228464|ref|NP_001084268.1| minesin-like protein [Xenopus laevis], gi|13235654|emb|CAC33801.1| ...
0.0 [92..705] [4..570]
gi|4512330 - gi|4512330|dbj|BAA75243.1| KIF1B-beta [Mus musculus]
0.0 [99..641] [2..472]
gi|8248421 - gi|8248421|gb|AAF74192.1|AF247761_1 kinesin superfamily member DUnc104 [Drosophila melanogaster]
0.0 [101..599] [2..450]
gi|32413078, gi|... - gi|32413078|ref|XP_327019.1| hypothetical protein [Neurospora crassa], gi|28922174|gb|EAA31425.1| hy...
gi|85098745 - gi|85098745|ref|XP_960661.1| hypothetical protein [Neurospora crassa OR74A]
0.0 [100..616] [11..483]
KRP85_STRPU - Kinesin-II 85 kDa subunit OS=Strongylocentrotus purpuratus GN=KRP85 PE=1 SV=1
0.0 [102..705] [10..568]

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Predicted Domain #1
Region A:
Residues: [1-71]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MIQKMSPSLR RPSTRSSSGS SNIPQSPSVR STSSFSNLTR NSIRSTSNSG SQSISASSTR  60
   61 SNSPLRSVSA K

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below are all of our de novo (Rosetta) predictions for this domain.
Click here to view only most confident match.

    MCM
Score
SCOP
Match
SCOP Description
View Download 0.622 a.35.1 lambda repressor-like DNA-binding domains
View Download 0.530 a.60.1 SAM/Pointed domain
View Download 0.469 a.65.1 Annexin
View Download 0.402 a.153.1 Nuclear receptor coactivator interlocking domain
View Download 0.352 a.24.13 Domain of the SRP/SRP receptor G-proteins
View Download 0.351 a.46.2 Nucleoside phosphorylase/phosphoribosyltransferase N-terminal domain
View Download 0.344 a.12.1 Kix domain of CBP (creb binding protein)
View Download 0.340 a.4.5 "Winged helix" DNA-binding domain
View Download 0.337 a.58.1 Chemotaxis receptor methyltransferase CheR, N-terminal domain
View Download 0.330 a.60.3 C-terminal domain of RNA polymerase alpha subunit
View Download 0.312 d.43.1 Elongation factor Ts (EF-Ts), dimerisation domain
View Download 0.299 a.48.3 Conserved domain common to transcription factors TFIIS, elongin A, CRSP70
View Download 0.287 d.43.1 Elongation factor Ts (EF-Ts), dimerisation domain
View Download 0.281 a.60.12 DNA polymerase beta-like, second domain
View Download 0.270 a.4.5 "Winged helix" DNA-binding domain
View Download 0.262 a.77.1 DEATH domain
View Download 0.245 a.7.6 Ribosomal protein S20
View Download 0.233 a.4.1 Homeodomain-like
View Download 0.228 a.52.1 Bifunctional inhibitor/lipid-transfer protein/seed storage 2S albumin
View Download 0.227 a.144.1 PABC (PABP) domain
View Download 0.215 a.4.5 "Winged helix" DNA-binding domain
View Download 0.209 a.46.1 Methionine synthase domain
View Download 0.204 a.39.1 EF-hand

Predicted Domain #2
Region A:
Residues: [72-507]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 SDPFLHPGRI RIRRSDSINN NSRKNDTYTG SITVTIRPKP RSVGTSRDHV GLKSPRYSQP  60
   61 RSNSHHGSNT FVRDPWFITN DKTIVHEEIG EFKFDHVFAS HCTNLEVYER TSKPMIDKLL 120
  121 MGFNATIFAY GMTGSGKTFT MSGNEQELGL IPLSVSYLFT NIMEQSMNGD KKFDVIISYL 180
  181 EIYNERIYDL LESGLEESGS RISTPSRLYM SKSNSNGLGV ELKIRDDSQY GVKVIGLTER 240
  241 RCESSEELLR WIAVGDKSRK IGETDYNARS SRSHAIVLIR LTSTNVKNGT SRSSTLSLCD 300
  301 LAGSERATGQ QERRKEGSFI NKSLLALGTV ISKLSADKMN SVGSNIPSPS ASGSSSSSGN 360
  361 ATNNGTSPSN HIPYRDSKLT RLLQPALSGD SIVTTICTVD TRNDAAAETM NTLRFASRAK 420
  421 NVALHVSKKS IISNGN

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 562.228787
Match: 1gojA_
Description: Kinesin
Matching Structure (courtesy of the PDB):

Predicted Domain #3
Region A:
Residues: [508-706]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 NDGDKDRTIE LLRRQLEEQR RMISELKNRS NIGEPLTKSS NESTYKDIKA TGNDGDPNLA  60
   61 LMRAENRVLK YKLENCEKLL DKDVVDLQDS EIMEIVEMLP FEVGTLLETK FQGLESQIRQ 120
  121 YRKYTQKLED KIMALEKSGH TAMSLTGCDG TEVIELQKML ERKDKMIEAL QSAKRLRDRA 180
  181 LKPLINTQQS PHPVVDNDK

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 11.69897
Match: 1i84S_
Description: Heavy meromyosin subfragment
Matching Structure (courtesy of the PDB):

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle