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View Structure Prediction Details

Protein: GLR1
Organism: Saccharomyces cerevisiae
Length: 483 amino acids
Reference: Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for GLR1.

Description E-value Query
Range
Subject
Range
CE31971 - dihydrolipoamide dehydrogenase status:Confirmed UniProt:O17953 protein_id:CAB05249.2
0.0 [2..481] [9..481]
DLDH1_ARATH - Dihydrolipoyl dehydrogenase 1, mitochondrial OS=Arabidopsis thaliana GN=LPD1 PE=1 SV=2
0.0 [5..481] [25..495]
GSHR_YEAST - Glutathione reductase OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=GLR1 PE=1 SV=2
GLR1 - Cytosolic and mitochondrial glutathione oxidoreductase, converts oxidized glutathione to reduced glu...
0.0 [1..483] [1..483]
DLD - dihydrolipoamide dehydrogenase
0.0 [2..481] [20..496]
GSHRP_TOBAC - Glutathione reductase, chloroplastic (Fragment) OS=Nicotiana tabacum GN=GOR PE=1 SV=1
0.0 [2..483] [54..532]
DLDH_CANLF - Dihydrolipoyl dehydrogenase, mitochondrial OS=Canis lupus familiaris GN=DLD PE=1 SV=1
gi|55742732 - ref|NP_001003294.1| dihydrolipoamide: NAD+ oxidoreductase [Canis familiaris]
0.0 [2..481] [20..496]
gi|2425107 - gi|2425107|gb|AAB70837.1| glutathione reductase (NADPH) [Vitis vinifera]
0.0 [8..483] [71..539]

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Predicted Domain #1
Region A:
Residues: [1-63]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MLSATKQTFR SLQIRTMSTN TKHYDYLVIG GGSGGVASAR RAASYGAKTL LVEAKALGGT  60
   61 CVN

[Run NCBI BLAST on this sequence.]

Region B:
Residues: [117-171]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 HRLNGIYQKN LEKEKVDVVF GWARFNKDGN VEVQKRDNTT EVYSANHILV ATGGK

[Run NCBI BLAST on this sequence.]

Region C:
Residues: [296-369]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 KSHLGMGSEN VGIKLNSHDQ IIADEYQNTN VPNIYSLGDV VGKVELTPVA IAAGRKLSNR  60
   61 LFGPEKFRND KLDY

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 1394.0
Match: 1grt__
Description: Glutathione reductase
Matching Structure (courtesy of the PDB):

Predicted Domain #2
Region A:
Residues: [64-116]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 VGCVPKKVMW YASDLATRVS HANEYGLYQN LPLDKEHLTF NWPEFKQKRD AYV

[Run NCBI BLAST on this sequence.]

Region B:
Residues: [172-232]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 AIFPENIPGF ELGTDSDGFF RLEEQPKKVV VVGAGYIGIE LAGVFHGLGS ETHLVIRGET  60
   61 V

[Run NCBI BLAST on this sequence.]

Region C:
Residues: [246-295]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 DHYVKEGINV HKLSKIVKVE KNVETDKLKI HMNDSKSIDD VDELIWTIGR 

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 1394.0
Match: 1grt__
Description: Glutathione reductase
Matching Structure (courtesy of the PDB):

Predicted Domain #3
Region A:
Residues: [233-245]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 LRKFDECIQN TIT

[Run NCBI BLAST on this sequence.]

Region B:
Residues: [370-483]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 ENVPSVIFSH PEAGSIGISE KEAIEKYGKE NIKVYNSKFT AMYYAMLSEK SPTRYKIVCA  60
   61 GPNEKVVGLH IVGDSSAEIL QGFGVAIKMG ATKADFDNCV AIHPTSAEEL VTMR

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 1394.0
Match: 1grt__
Description: Glutathione reductase
Matching Structure (courtesy of the PDB):

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle