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View Structure Prediction Details

Protein: GPI2
Organism: Saccharomyces cerevisiae
Length: 280 amino acids
Reference: Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for GPI2.

Description E-value Query
Range
Subject
Range
PIGC - phosphatidylinositol glycan anchor biosynthesis, class C
gi|61361835, gi|... - gi|61361840|gb|AAX42112.1| phosphatidylinositol glycan class C [synthetic construct], gi|61361835|gb...
5.0E-77 [5..280] [13..291]
gi|30584777, gi|... - gi|60653763|gb|AAX29575.1| phosphatidylinositol glycan class C [synthetic construct], gi|60653761|gb...
7.0E-77 [5..280] [13..291]
PIGC_MOUSE - Phosphatidylinositol N-acetylglucosaminyltransferase subunit C OS=Mus musculus GN=Pigc PE=2 SV=1
8.0E-77 [5..280] [13..291]
gi|190407877 - gi|190407877|gb|EDV11142.1| phosphatidylinositol N-acetylglucosaminyltransferase GPI2 subunit [Sacch...
GPI2 - Protein involved in the synthesis of N-acetylglucosaminyl phosphatidylinositol (GlcNAc-PI), the firs...
gi|151942720 - gi|151942720|gb|EDN61066.1| glycosylphosphatidylinositol anchor biosynthesis [Saccharomyces cerevisi...
gi|207340538 - gi|207340538|gb|EDZ68861.1| YPL076Wp-like protein [Saccharomyces cerevisiae AWRI1631]
GPI2_YEAST - Phosphatidylinositol N-acetylglucosaminyltransferase GPI2 subunit OS=Saccharomyces cerevisiae (strai...
5.0E-74 [1..280] [1..280]
gi|23092908, gi|... - gi|24656747|ref|NP_647804.1| CG12077 [Drosophila melanogaster], gi|23092908|gb|AAF47758.2| CG12077 [...
5.0E-70 [3..280] [9..287]
CE23990 - status:Partially_confirmed UniProt:O01259 protein_id:CAA92490.2
3.0E-63 [6..277] [7..277]
GPI2_SCHPO - Phosphatidylinositol N-acetylglucosaminyltransferase GPI2 subunit OS=Schizosaccharomyces pombe (stra...
gpi2 - pig-C
3.0E-60 [3..279] [35..319]

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Predicted Domain #1
Region A:
Residues: [1-184]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MTRSPWKRLL WLKQEYPDNY TDPSFIELRA RQKAESNQKS DRKLSEAARA QIRLDFISFY  60
   61 QTILNTSFIY ITFTYIYYYG FDPIPPTIFL SFITLIISRT KVDPLLSSFM DVKSSLIITF 120
  121 AMLTLSPVLK SLSKTTASDS IWTLSFWLTL WYIFVISSTK SKDKPSNLST NILVALVAVL 180
  181 SSRL

[Run NCBI BLAST on this sequence.]

Detection Method: MSA

Shown below are all of our structure predictions for this domain.
Click here to view only most confident match.

Found no structure predictions for this domain.

Predicted Domain #2
Region A:
Residues: [185-280]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 STTIDVFCFL LICIQLNIIL PTYLSVTNKV VPIISNIIVY SFLNVALGWI YMLLIFFASV  60
   61 FYITVLPKWF IYWKINYHKR DNDLLSTWDA RTPILD

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below are all of our de novo (Rosetta) predictions for this domain.
Click here to view only most confident match.

    MCM
Score
SCOP
Match
SCOP Description
View Download 0.596 a.74.1 Cyclin-like
View Download 0.603 a.47.2 t-snare proteins
View Download 0.678 a.24.17 Group V grass pollen allergen
View Download 0.642 f.15.1 Small-conductance potassium channel
View Download 0.623 c.47.2 RNA 3'-terminal phosphate cyclase, RPTC, insert domain
View Download 0.678 a.24.17 Group V grass pollen allergen
View Download 0.642 f.15.1 Small-conductance potassium channel
View Download 0.623 c.47.2 RNA 3'-terminal phosphate cyclase, RPTC, insert domain
View Download 0.603 a.47.2 t-snare proteins
View Download 0.596 a.74.1 Cyclin-like
View Download 0.585 a.2.7 tRNA-binding arm
View Download 0.571 a.12.1 Kix domain of CBP (creb binding protein)
View Download 0.551 a.69.3 1-deoxy-D-xylulose-5-phosphate reductoisomerase, C-terminal domain
View Download 0.549 a.74.1 Cyclin-like
View Download 0.521 a.7.3 Succinate dehydrogenase/fumarate reductase flavoprotein C-terminal domain
View Download 0.494 a.7.8 GAT domain
View Download 0.490 f.34.1 Mechanosensitive channel protein MscS (YggB), transmembrane region
View Download 0.485 d.52.7 Ribosome-binding factor A, RbfA
View Download 0.475 d.17.4 NTF2-like
View Download 0.472 a.61.1 Retroviral matrix proteins
View Download 0.471 d.79.2 Tubulin/Dihydroxyacetone kinase C-terminal domain
View Download 0.470 f.36.1 Neurotransmitter-gated ion-channel pransmembrane pore
View Download 0.447 a.39.1 EF-hand
View Download 0.424 a.7.5 Tubulin chaperone cofactor A
View Download 0.417 d.8.1 Urease, gamma-subunit
View Download 0.411 g.53.1 TAZ domain
View Download 0.395 b.61.3 D-aminopeptidase, middle and C-terminal domains
View Download 0.372 a.142.1 PTS-regulatory domain, PRD
View Download 0.371 d.105.1 Clathrin adaptor appendage, alpha and beta chain-specific domain
View Download 0.366 a.121.1 Tetracyclin repressor-like, C-terminal domain
View Download 0.357 b.1.1 Immunoglobulin
View Download 0.356 a.7.2 Enzyme IIa from lactose specific PTS, IIa-lac
View Download 0.355 a.118.1 ARM repeat
View Download 0.348 d.105.1 Clathrin adaptor appendage, alpha and beta chain-specific domain
View Download 0.342 d.200.1 Integrin beta tail domain
View Download 0.338 a.5.4 Elongation factor TFIIS domain 2
View Download 0.334 a.4.5 "Winged helix" DNA-binding domain
View Download 0.330 b.1.2 Fibronectin type III
View Download 0.317 d.78.1 RPB5-like RNA polymerase subunit
View Download 0.311 d.24.1 Pili subunits
View Download 0.310 a.2.8 Eukaryotic DNA topoisomerase I, dispensable insert domain
View Download 0.306 a.118.11 Cytochrome c oxidase subunit E
View Download 0.303 a.24.13 Domain of the SRP/SRP receptor G-proteins
View Download 0.301 d.68.1 Translation initiation factor IF3, C-terminal domain
View Download 0.296 a.26.1 4-helical cytokines
View Download 0.294 c.78.2 Aspartate/glutamate racemase
View Download 0.292 d.81.1 Glyceraldehyde-3-phosphate dehydrogenase-like, C-terminal domain
View Download 0.288 a.5.6 Hypothetical protein MTH1615
View Download 0.285 a.27.1 Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases
View Download 0.284 a.8.2 Plasmid maintenance system epsilon/zeta, antidote epsilon subunit
View Download 0.281 a.160.1 Poly(A) polymerase, middle domain
View Download 0.279 a.112.1 Description not found.
View Download 0.277 a.177.1 Sigma2 domain of RNA polymerase sigma factors
View Download 0.277 d.110.3 PYP-like sensor domain (PAS domain)
View Download 0.276 a.64.1 Saposin
View Download 0.273 a.24.9 alpha-catenin/vinculin
View Download 0.273 a.41.1 Domain of poly(ADP-ribose) polymerase
View Download 0.272 a.64.1 Saposin
View Download 0.270 b.1.2 Fibronectin type III
View Download 0.264 a.45.1 Glutathione S-transferase (GST), C-terminal domain
View Download 0.260 a.4.5 "Winged helix" DNA-binding domain
View Download 0.259 a.16.1 S15/NS1 RNA-binding domain
View Download 0.258 d.81.1 Glyceraldehyde-3-phosphate dehydrogenase-like, C-terminal domain
View Download 0.252 a.3.1 Cytochrome c
View Download 0.251 a.29.2 Bromodomain
View Download 0.251 a.71.2 Helical domain of Sec23/24
View Download 0.249 d.38.1 Thioesterase/thiol ester dehydrase-isomerase
View Download 0.247 a.45.1 Glutathione S-transferase (GST), C-terminal domain
View Download 0.247 a.29.3 Acyl-CoA dehydrogenase C-terminal domain-like
View Download 0.244 a.71.1 Endoplasmic reticulum protein ERP29, C-domain
View Download 0.242 i.1.1 Ribosome and ribosomal fragments
View Download 0.241 d.110.3 PYP-like sensor domain (PAS domain)
View Download 0.240 a.179.1 Replisome organizer (g39p helicase loader/inhibitor protein)
View Download 0.239 a.26.1 4-helical cytokines
View Download 0.236 d.39.1 Dynein light chain 8 (DLC8)
View Download 0.235 a.61.1 Retroviral matrix proteins
View Download 0.231 d.52.3 Prokaryotic type KH domain (KH-domain type II)
View Download 0.230 d.110.4 SNARE-like
View Download 0.226 a.30.2 Homodimeric domain of signal transducing histidine kinase
View Download 0.224 a.24.10 Histidine-containing phosphotransfer domain, HPT domain
View Download 0.222 a.52.1 Bifunctional inhibitor/lipid-transfer protein/seed storage 2S albumin
View Download 0.217 a.7.7 BAG domain
View Download 0.216 a.19.1 Fertilization protein
View Download 0.216 a.25.1 Ferritin-like
View Download 0.206 d.38.1 Thioesterase/thiol ester dehydrase-isomerase


YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle