YRC Public Data Repository - Protein Structure Prediction

Protein:	YTA6
Organism:	Saccharomyces cerevisiae
Length:	754 amino acids
Reference:	Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for YTA6.

Description	E-value	Query Range	Subject Range
TBP6_YEAST - Probable 26S protease subunit YTA6 OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=YTA6 ... YTA6 - Putative ATPase of the CDC48/PAS1/SEC18 (AAA) family, localized to the cortex of mother cells but no... gi\|190407879 - gi\|190407879\|gb\|EDV11144.1\| hypothetical protein SCRG_02420 [Saccharomyces cerevisiae RM11-1a]	0.0	[1..754]	[1..754]
Y1297_ARCFU - Cell division cycle protein 48 homolog AF_1297 OS=Archaeoglobus fulgidus (strain ATCC 49558 / VC-16 ... Y1297_ARCFU, YC9... - (O28972) Cell division cycle protein 48 homolog AF1297, Cell division cycle protein 48 homolog AF_12...	0.0	[192..749]	[162..728]
CDC48_SOYBN - Cell division cycle protein 48 homolog OS=Glycine max GN=CDC48 PE=2 SV=1	0.0	[66..752]	[64..770]
gi\|18159541, gi\|... - gi\|18312110\|ref\|NP_558777.1\| AAA family ATPase, CDC48 subfamily protein [Pyrobaculum aerophilum str....	0.0	[153..748]	[124..713]
TERA_DANRE - Transitional endoplasmic reticulum ATPase OS=Danio rerio GN=vcp PE=1 SV=1	0.0	[171..752]	[161..765]
gi\|26350783 - gi\|26350783\|dbj\|BAC39028.1\| unnamed protein product [Mus musculus]	0.0	[171..752]	[78..682]
gi\|15920392, gi\|... - gi\|15920392\|ref\|NP_376061.1\| hypothetical protein ST0209 [Sulfolobus tokodaii str. 7], gi\|15621174\|d...	0.0	[109..748]	[6..673]
gi\|7507776 - gi\|7507776\|pir\|\|T16867 probable cytochrome P450 T13C5.1 [similarity] - Caenorhabditis elegans	0.0	[153..752]	[183..802]
CDC48_CAPAN - Cell division cycle protein 48 homolog OS=Capsicum annuum GN=CAFP PE=2 SV=1	0.0	[153..752]	[151..768]
TER94-PA - The gene TER94 is referred to in FlyBase by the symbol Dmel\TER94 (CG2331, FBgn0261014). It is a pro... gi\|220942716 - gi\|220942716\|gb\|ACL83901.1\| TER94-PA [synthetic construct]	0.0	[156..752]	[146..763]

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Predicted Domain #1

Region A:
Residues: [1-215]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MAHEKFSIPE NFTLAQSLQL LYSVVKNQYK NLADLIINSK GNKDTVTYGK IHKNLDTLLV  60
   61 YVNEGLRKIE KTYTLKKGLG NLVVDHPELR SIIEDFQILG QDIRIARRKA ETLMAEGNGS 120
  121 PSLSSSSSVL GLGTGNGLRF PKLWRMGSKR DKLKEADEKE AKINKQADNI RRARKLEEEK 180
  181 KLGAKLQYER DLELQREKLI ELKVKEKVEF EVAQK

[Run NCBI BLAST on this sequence.]

Detection Method:

MSA

Shown below is our most confident prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #2

Region A:
Residues: [216-374]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 LEEERVKREE EERKHREQAE KKRISTLKHE RKTNYKSRAS LDNFSSSSKS SGKIDNSLIK  60
   61 RRSLDVVRTS GERVRTPVRK SMEAAEIGMA AQLAWSQYQN GANHSKVSNN GSHSNELQIR 120
  121 YKPTPPLKKR YDYKKPTVNR PIIKSPTLNR QNSKSSRNI

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	43.927757
Match:	1ksfX_
Description:	N-terminal, ClpS-binding domain of ClpA, an Hsp100 chaperone; ClpA, an Hsp100 chaperone, AAA+ modules
Matching Structure (courtesy of the PDB):

Predicted Domain #3

Region A:
Residues: [375-518]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 PTNSKLKASK SNTNKVSRRN EQNLEPSSPV LVSATAVPAE SKPMRSKSGT PDKESSASSS  60
   61 LDSRKEDILK SVQGVDRNAC EQILNEILVT DEKVYWEDIA GLRNAKNSLK EAVVYPFLRP 120
  121 DLFKGLREPV RGMLLFGPPG TGKT

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	43.927757
Match:	1ksfX_
Description:	N-terminal, ClpS-binding domain of ClpA, an Hsp100 chaperone; ClpA, an Hsp100 chaperone, AAA+ modules
Matching Structure (courtesy of the PDB):

Predicted Domain #4

Region A:
Residues: [519-647]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MIAKAVATES NSTFFSVSAS SLLSKYLGES EKLVRALFYM AKKLSPSIIF IDEIDSMLTA  60
   61 RSDNENESSR RIKTELLIQW SSLSSATAQS EDRNNTLDSR VLVLGATNLP WAIDDAARRR 120
  121 FSRKLYIPL

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	482.24799
Match:	1e32A_
Description:	Membrane fusion atpase p97 N-terminal domain , P97-Nn; Membrane fusion atpase p97, D1 domain; Membrane fusion atpase p97 domain 2, P97-Nc
Matching Structure (courtesy of the PDB):

Predicted Domain #5

Region A:
Residues: [648-754]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 PDYETRLYHL KRLMAKQKNS LQDLDYELIT EMTEGFSGSD LTSLAKEAAM EPIRDLGDKL  60
   61 MFADFDKIRG IEIKDFQNAL LTIKKSVSSE SLQKYEEWSS KFGSNGS

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	482.24799
Match:	1e32A_
Description:	Membrane fusion atpase p97 N-terminal domain , P97-Nn; Membrane fusion atpase p97, D1 domain; Membrane fusion atpase p97 domain 2, P97-Nc
Matching Structure (courtesy of the PDB):

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits