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View Structure Prediction Details

Protein: UBP16
Organism: Saccharomyces cerevisiae
Length: 499 amino acids
Reference: Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for UBP16.

Description E-value Query
Range
Subject
Range
UBP16 - Deubiquitinating enzyme anchored to the outer mitochondrial membrane, probably not important for gen...
UBP16_YEAST - Ubiquitin carboxyl-terminal hydrolase 16 OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN...
5.0E-86 [1..499] [1..499]
gi|15208127 - gi|15208127|dbj|BAB63088.1| hypothetical protein [Macaca fascicularis]
9.0E-83 [5..474] [72..543]
USP22 - ubiquitin specific peptidase 22
2.0E-76 [33..455] [219..593]
gi|7673618 - gi|7673618|gb|AAF66953.1|AF229643_1 ubiquitin specific protease [Mus musculus]
6.0E-76 [40..467] [152..525]
UBP44_DANRE - Ubiquitin carboxyl-terminal hydrolase 44 OS=Danio rerio GN=usp44 PE=2 SV=1
1.0E-72 [3..450] [250..684]

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Predicted Domain #1
Region A:
Residues: [1-447]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MSWIKNVTES PTSLIKKVSC GLIIAASLYA IAPSLSALVF GDSKQSIGKY TTVGLINRGN  60
   61 DCFITSSLQG LAGIPRFVEY LKRIRTVLLE LETKLSNNAK GDNPTVDNTT RHSRLENSSN 120
  121 SLAPLHESLT SLILDLISVK DRKTSISPKI VINTLESIFK SKISSKQNDA HEFTLILLQT 180
  181 LQEERSKLID YSKQICNLNI PKFPFEGETS KFLVCLKCKG LSEPSYKQTF IRELSVPQQT 240
  241 SENLSNILAH DETEIIDDYS CLICQIRAIL NHEEYRNFKD CTPDEILMLD RLKNYATKAP 300
  301 INENLPFEVE QYVKRYSKGN LQVSNIKGKV IKKDVVVQLP DILIVHLSRS TFNGITYSRN 360
  361 PCNVKFGERI TLSEYTLAES GTITENRQVK YNLKSVVKHT GSHSSGHYMC YRRKTEIRFG 420
  421 KEDESSFRRA PVVNNEVNKN REQNVAH

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 36.522879
Match: 1nbfA_
Description: Ubiquitin carboxyl-terminal hydrolase 7 (USP7, HAUSP)
Matching Structure (courtesy of the PDB):

Predicted Domain #2
Region A:
Residues: [448-499]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 NDYKKSRYKK VKNALRYPYW QISDTAIKES TASTVLNEQK YAYMLYYERV NK

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

    MCM
Score
GO
Score
GO
Term
SCOP
Match
SCOP Description
View Download 0.805 0.127 protein deubiquitination a.60.1 SAM/Pointed domain


YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle