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View Structure Prediction Details

Protein: VTC3
Organism: Saccharomyces cerevisiae
Length: 835 amino acids
Reference: Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for VTC3.

Description E-value Query
Range
Subject
Range
VTC3 - Subunit of the vacuolar transporter chaperone (VTC) complex involved in membrane trafficking, vacuol...
VTC3_YEAST - Vacuolar transporter chaperone 3 OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=VTC3 PE...
0.0 [1..835] [1..835]
gi|28918255, gi|... - gi|32415409|ref|XP_328184.1| hypothetical protein ( (AL356815) conserved hypothetical protein [Neuro...
gi|85083710 - gi|85083710|ref|XP_957168.1| hypothetical protein NCU01745 [Neurospora crassa OR74A]
0.0 [1..813] [1..783]
gi|7507776 - gi|7507776|pir||T16867 probable cytochrome P450 T13C5.1 [similarity] - Caenorhabditis elegans
0.0 [1..802] [1..772]
VTC2_SCHPO - Vacuolar transporter chaperone 2 OS=Schizosaccharomyces pombe (strain 972 / ATCC 24843) GN=vtc2 PE=1...
SPAC14C4.11 - polyphosphate synthetase
0.0 [1..807] [1..722]
gi|13182949 - gi|13182949|gb|AAK15002.1|AF233343_5 unknown [Candida glabrata]
0.0 [242..835] [1..585]

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Predicted Domain #1
Region A:
Residues: [1-179]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MLFGIKLAND VYPPWKDSYI DYERLKKLLK ESVIHDGRSS VDSWSERNES DFVEALDKEL  60
   61 EKVYTFQISK YNAVLRKLDD LEENTKSAEK IQKINSEQFK NTLEECLDEA QRLDNFDRLN 120
  121 FTGFIKIVKK HDKLHPNYPS VKSLLQVRLK ELPFNNSEEY SPLLYRISYL YEFLRSNYD

[Run NCBI BLAST on this sequence.]

Detection Method: Pfam
Confidence: 53.443697
Match: PF03105
Description: SPX domain

Shown below are all of our structure predictions for this domain.
Click here to view only most confident match.

Found no structure predictions for this domain.

Predicted Domain #2
Region A:
Residues: [180-254]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 HPNTVSKSLA STSKLSHFSN LEDASFKSYK FWVHDDNIME VKARILRHLP ALVYASVPNE  60
   61 NDDFVDNLES DVRVQ

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below are all of our de novo (Rosetta) predictions for this domain.
Click here to view only most confident match.

    MCM
Score
SCOP
Match
SCOP Description
View Download 0.648 d.50.1 dsRNA-binding domain-like
View Download 0.793 d.49.1 Signal recognition particle alu RNA binding heterodimer, SRP9/14
View Download 0.793 d.49.1 Signal recognition particle alu RNA binding heterodimer, SRP9/14
View Download 0.713 d.9.2 Description not found.
View Download 0.713 d.9.2 Description not found.
View Download 0.648 d.50.1 dsRNA-binding domain-like
View Download 0.629 d.50.1 dsRNA-binding domain-like
View Download 0.629 d.50.1 dsRNA-binding domain-like
View Download 0.612 d.49.1 Signal recognition particle alu RNA binding heterodimer, SRP9/14
View Download 0.594 b.122.1 PUA domain-like
View Download 0.546 d.9.1 Interleukin 8-like chemokines
View Download 0.541 d.9.1 Interleukin 8-like chemokines
View Download 0.501 d.51.1 Eukaryotic type KH-domain (KH-domain type I)
View Download 0.501 d.93.1 SH2 domain
View Download 0.446 d.129.1 TATA-box binding protein-like
View Download 0.444 b.40.4 Nucleic acid-binding proteins
View Download 0.436 a.64.1 Saposin
View Download 0.410 a.22.1 Histone-fold
View Download 0.409 d.50.1 dsRNA-binding domain-like
View Download 0.343 d.9.2 Description not found.
View Download 0.332 b.34.5 Translation proteins SH3-like domain
View Download 0.327 d.16.1 FAD-linked reductases, C-terminal domain
View Download 0.324 d.50.1 dsRNA-binding domain-like
View Download 0.320 g.18.1 Complement control module/SCR domain
View Download 0.312 d.105.1 Clathrin adaptor appendage, alpha and beta chain-specific domain
View Download 0.311 c.47.1 Thioredoxin-like
View Download 0.301 d.129.2 Phosphoglucomutase, C-terminal domain
View Download 0.298 g.5.1 Midkine
View Download 0.294 b.34.5 Translation proteins SH3-like domain
View Download 0.264 a.4.5 "Winged helix" DNA-binding domain
View Download 0.258 d.17.1 Cystatin/monellin
View Download 0.258 d.50.2 Porphobilinogen deaminase (hydroxymethylbilane synthase), C-terminal domain
View Download 0.253 b.1.2 Fibronectin type III
View Download 0.242 b.1.1 Immunoglobulin
View Download 0.238 d.110.4 SNARE-like
View Download 0.236 a.3.1 Cytochrome c
View Download 0.235 b.84.2 Rudiment single hybrid motif
View Download 0.225 c.102.1 Cell-division inhibitor MinC, N-terminal domain
View Download 0.223 b.55.1 PH domain-like
View Download 0.217 b.40.4 Nucleic acid-binding proteins
View Download 0.213 d.200.1 Integrin beta tail domain
View Download 0.208 b.55.1 PH domain-like

Predicted Domain #3
Region A:
Residues: [255-552]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 PEARLNIGSK SNSLSSDGNS NQDVEIGKSK SVIFPQSYDP TITTLYFDND FFDLYNNRLL  60
   61 KISGAPTLRL RWIGKLLDKP DIFLEKRTFT ENTETGNSSF EEIRLQMKAK FINNFIFKND 120
  121 PSYKNYLINQ LRERGTQKEE LEKLSRDFDN IQNFIVEEKL QPVLRATYNR TAFQIPGDQS 180
  181 IRVTIDSNIM YIREDSLDKN RPIRNPENWH RDDIDSNIPN PLRFLRAGEY SKFPYSVMEI 240
  241 KVINQDNSQM PNYEWIKDLT NSHLVNEVPK FSLYLQGVAS LFGEDDKYVN ILPFWLPD

[Run NCBI BLAST on this sequence.]

Detection Method: MSA

Shown below are all of our structure predictions for this domain.
Click here to view only most confident match.

Found no structure predictions for this domain.

Predicted Domain #4
Region A:
Residues: [553-659]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 LETDIRKNPQ EAYEEEKKTL QKQKSIHDKL DNMRRLSKIS VPDGKTTERQ GQKDQNTRHV  60
   61 IADLEDHESS DEEGTALPKK SAVKKGKKFK TNAAFLKILA GKNISEN

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below are all of our de novo (Rosetta) predictions for this domain.
Click here to view only most confident match.

    MCM
Score
SCOP
Match
SCOP Description
View Download 0.393 a.7.7 BAG domain
View Download 0.506 a.130.1 Chorismate mutase II
View Download 0.516 a.7.2 Enzyme IIa from lactose specific PTS, IIa-lac
View Download 0.360 a.145.1 Flagellar transcriptional activator FlhD
View Download 0.516 a.7.2 Enzyme IIa from lactose specific PTS, IIa-lac
View Download 0.506 a.130.1 Chorismate mutase II
View Download 0.393 a.7.7 BAG domain
View Download 0.387 a.23.1 HSC20 (HSCB), C-terminal oligomerisation domain
View Download 0.387 a.23.1 HSC20 (HSCB), C-terminal oligomerisation domain
View Download 0.360 a.145.1 Flagellar transcriptional activator FlhD
View Download 0.347 a.181.1 Antibiotic binding domain of TipA-like multidrug resistance regulators
View Download 0.317 a.100.1 6-phosphogluconate dehydrogenase C-terminal domain-like
View Download 0.308 i.11.1 Computational models partly based on NMR data
View Download 0.306 a.100.1 6-phosphogluconate dehydrogenase C-terminal domain-like
View Download 0.305 d.82.2 Frataxin-like
View Download 0.287 c.78.2 Aspartate/glutamate racemase
View Download 0.266 a.143.1 RNA polymerase omega subunit
View Download 0.265 a.24.3 Cytochromes
View Download 0.257 a.74.1 Cyclin-like
View Download 0.254 a.45.1 Glutathione S-transferase (GST), C-terminal domain
View Download 0.247 c.5.1 MurCD N-terminal domain
View Download 0.245 a.1.1 Globin-like
View Download 0.240 c.23.1 CheY-like
View Download 0.223 a.2.1 GreA transcript cleavage protein, N-terminal domain
View Download 0.220 a.27.1 Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases
View Download 0.220 c.23.16 Class I glutamine amidotransferase-like
View Download 0.219 f.36.1 Neurotransmitter-gated ion-channel pransmembrane pore
View Download 0.213 a.35.1 lambda repressor-like DNA-binding domains
View Download 0.206 a.4.5 "Winged helix" DNA-binding domain

Predicted Domain #5
Region A:
Residues: [660-835]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 GNDPYSDDTD SASSFQLPPG VKKPVHLLKN AGPVKVEAKV WLANERTFNR WLSVTTLLSV  60
   61 LTFSIYNSVQ KAEFPQLADL LAYVYFFLTL FCGVWAYRTY LKRLTLIKGR SGKHLDAPVG 120
  121 PILVAVVLIV TLVVNFSVAF KEAARRERGL VNVSSQPSLP RTLKPIQDFI FNLVGE

[Run NCBI BLAST on this sequence.]

Detection Method: MSA

Shown below are all of our structure predictions for this domain.
Click here to view only most confident match.

Found no structure predictions for this domain.


YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle