| Protein: | PYK2 |
| Organism: | Saccharomyces cerevisiae |
| Length: | 506 amino acids |
| Reference: | Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076 |
Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for PYK2.
| Description | E-value | Query Range |
Subject Range |
|
|
0.0 | [1..502] | [56..564] |
|
|
0.0 | [1..502] | [22..530] |
|
|
0.0 | [1..502] | [22..530] |
|
|
0.0 | [1..502] | [22..530] |
|
Region A: Residues: [1-91] |
1 11 21 31 41 51
| | | | | |
1 MPESRLQRLA NLKIGTPQQL RRTSIIGTIG PKTNSCEAIT ALRKAGLNII RLNFSHGSYE 60
61 FHQSVIENAV KSEQQFPGRP LAIALDTKGP E
|
|
Region B: Residues: [188-362] |
1 11 21 31 41 51
| | | | | |
1 VDLPPLSAKD MKDLQFGVRN GIHIVFASFI RTSEDVLSIR KALGSEGQDI KIISKIENQQ 60
61 GLDNFDEILE VTDGVMIARG DLGIEILAPE VLAIQKKLIA KCNLAGKPVI CATQMLDSMT 120
121 HNPRPTRAEV SDVGNAVLDG ADCVMLSGET AKGDYPVNAV NIMAATALIA ESTIA
|
| Detection Method: |  |
| Confidence: | 11000.0 |
| Match: | 1a3wA_ |
| Description: | Pyruvate kinase (PK); Pyruvate kinase, N-terminal domain; Pyruvate kinase, C-terminal domain |
Matching Structure (courtesy of the PDB): |
|
| Term | Confidence | Notes |
| pyruvate kinase activity | 5.30539631424432 | bayes_pls_golite062009 |
| phosphotransferase activity, alcohol group as acceptor | 3.74686803828771 | bayes_pls_golite062009 |
| kinase activity | 3.60311146880852 | bayes_pls_golite062009 |
| transferase activity, transferring phosphorus-containing groups | 3.2602140947877 | bayes_pls_golite062009 |
| substrate-specific transmembrane transporter activity | 2.49386405838309 | bayes_pls_golite062009 |
| transferase activity | 2.39042747917065 | bayes_pls_golite062009 |
| substrate-specific transporter activity | 2.35681897894387 | bayes_pls_golite062009 |
| hydroxymethyl-, formyl- and related transferase activity | 1.41686595651633 | bayes_pls_golite062009 |
| binding | 1.40856686140554 | bayes_pls_golite062009 |
| ADP binding | 1.23883289666587 | bayes_pls_golite062009 |
| glycine hydroxymethyltransferase activity | 1.09759860844913 | bayes_pls_golite062009 |
| hydrolase activity | 0.962445116339459 | bayes_pls_golite062009 |
| catalytic activity | 0.932947046865376 | bayes_pls_golite062009 |
| phosphoenolpyruvate carboxykinase activity | 0.777178963260734 | bayes_pls_golite062009 |
| protein binding | 0.438735017993357 | bayes_pls_golite062009 |
| lyase activity | 0.0456521871650777 | bayes_pls_golite062009 |
| phosphotransferase activity, paired acceptors | 0.0254711315719321 | bayes_pls_golite062009 |
| citrate (pro-3S)-lyase activity | 0.0039163158887896 | bayes_pls_golite062009 |
|
Region A: Residues: [92-187] |
1 11 21 31 41 51
| | | | | |
1 IRTGRTLNDQ DLYIPVDHQM IFTTDASFAN TSNDKIMYID YANLTKVIVP GRFIYVDDGI 60
61 LSFKVLQIID ESNLRVQAVN SGYIASHKGV NLPNTD
|
|
Region B: Residues: [363-506] |
1 11 21 31 41 51
| | | | | |
1 HLALYDDLRD ATPKPTSTTE TVAAAATAAI LEQDGKAIVV LSTTGNTARL LSKYRPSCPI 60
61 ILVTRHARTA RIAHLYRGVF PFLYEPKRLD DWGEDVHRRL KFGVEMARSF GMVDNGDTVV 120
121 SIQGFKGGVG HSNTLRISTV GQEF
|
| Detection Method: | |
| Confidence: | 11000.0 |
| Match: | 1a3wA_ |
| Description: | Pyruvate kinase (PK); Pyruvate kinase, N-terminal domain; Pyruvate kinase, C-terminal domain |
| Matching Structure (courtesy of the PDB): |
|
