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View Structure Prediction Details

Protein: GNT1
Organism: Saccharomyces cerevisiae
Length: 491 amino acids
Reference: Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for GNT1.

Description E-value Query
Range
Subject
Range
gi|190407619 - gi|190407619|gb|EDV10886.1| N-acetylglucosaminyltransferase [Saccharomyces cerevisiae RM11-1a]
gi|207340890 - gi|207340890|gb|EDZ69100.1| YOR320Cp-like protein [Saccharomyces cerevisiae AWRI1631]
GNT1_YEAST - Glucose N-acetyltransferase 1 OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=GNT1 PE=1 ...
GNT1 - N-acetylglucosaminyltransferase capable of modification of N-linked glycans in the Golgi apparatus
0.0 [1..491] [1..491]
GNT1A_KLULA - Glucose N-acetyltransferase 1-A OS=Kluyveromyces lactis (strain ATCC 8585 / CBS 2359 / DSM 70799 / N...
GNT1A_KLULA - Glucose N-acetyltransferase 1-A OS=Kluyveromyces lactis GN=GNT1-A PE=3 SV=1
0.0 [45..486] [56..454]
GUX4_ARATH - Putative UDP-glucuronate:xylan alpha-glucuronosyltransferase 4 OS=Arabidopsis thaliana GN=GUX4 PE=3 ...
3.0E-49 [19..278] [187..438]
gi|5541885 - gi|5541885|emb|CAB51130.1| putative galactinol synthase [Pisum sativum]
2.0E-44 [82..242] [11..162]
gi|4588376 - gi|4588376|gb|AAD26116.1|AF106954_1 galactinol synthase [Brassica napus]
3.0E-44 [63..242] [2..168]
gi|119599302, gi... - gi|496895|emb|CAA56073.1| glycogenin [Homo sapiens], gi|119599307|gb|EAW78901.1| glycogenin 1, isofo...
1.0E-43 [93..269] [5..168]
gi|32345700 - gi|32345700|gb|AAM96870.1| fagopyritol synthase 1 [Fagopyrum esculentum]
3.0E-43 [69..242] [2..166]

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Predicted Domain #1
Region A:
Residues: [1-82]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MRLISKRRIR FIVFILFGVL TVFVVSRLVV HFQYNQEIKF YKKYFQQRKD GLHEIYNPLE  60
   61 IKQIPKETID DLYTARLDKE LK

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below are all of our de novo (Rosetta) predictions for this domain.
Click here to view only most confident match.

    MCM
Score
SCOP
Match
SCOP Description
View Download 0.502 a.4.5 "Winged helix" DNA-binding domain
View Download 0.641 a.52.1 Bifunctional inhibitor/lipid-transfer protein/seed storage 2S albumin
View Download 0.632 a.16.1 S15/NS1 RNA-binding domain
View Download 0.599 a.24.13 Domain of the SRP/SRP receptor G-proteins
View Download 0.627 a.13.1 alpha-2-Macroglobulin receptor associated protein (RAP) domain 1
View Download 0.641 a.52.1 Bifunctional inhibitor/lipid-transfer protein/seed storage 2S albumin
View Download 0.632 a.16.1 S15/NS1 RNA-binding domain
View Download 0.627 a.13.1 alpha-2-Macroglobulin receptor associated protein (RAP) domain 1
View Download 0.599 a.24.13 Domain of the SRP/SRP receptor G-proteins
View Download 0.502 a.4.5 "Winged helix" DNA-binding domain
View Download 0.501 a.45.1 Glutathione S-transferase (GST), C-terminal domain
View Download 0.496 f.13.1 Family A G protein-coupled receptor-like
View Download 0.487 a.77.1 DEATH domain
View Download 0.472 a.101.1 Uteroglobin-like
View Download 0.446 a.112.1 Description not found.
View Download 0.442 a.52.1 Bifunctional inhibitor/lipid-transfer protein/seed storage 2S albumin
View Download 0.442 a.7.6 Ribosomal protein S20
View Download 0.431 a.7.2 Enzyme IIa from lactose specific PTS, IIa-lac
View Download 0.430 a.80.1 DNA polymerase III clamp loader subunits, C-terminal domain
View Download 0.425 a.24.17 Group V grass pollen allergen
View Download 0.411 a.16.1 S15/NS1 RNA-binding domain
View Download 0.391 f.15.1 Small-conductance potassium channel
View Download 0.387 a.27.1 Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases
View Download 0.379 a.64.1 Saposin
View Download 0.378 a.2.9 C-terminal UvrC-binding domain of UvrB
View Download 0.376 d.52.7 Ribosome-binding factor A, RbfA
View Download 0.375 a.7.7 BAG domain
View Download 0.372 a.4.1 Homeodomain-like
View Download 0.370 f.34.1 Mechanosensitive channel protein MscS (YggB), transmembrane region
View Download 0.369 a.77.1 DEATH domain
View Download 0.362 a.60.6 DNA polymerase beta, N-terminal domain-like
View Download 0.331 a.118.14 FliG
View Download 0.320 a.65.1 Annexin
View Download 0.315 a.60.8 HRDC-like
View Download 0.309 a.2.8 Eukaryotic DNA topoisomerase I, dispensable insert domain
View Download 0.304 a.68.1 Wiscott-Aldrich syndrome protein, WASP, C-terminal domain
View Download 0.301 a.60.6 DNA polymerase beta, N-terminal domain-like
View Download 0.299 a.80.1 DNA polymerase III clamp loader subunits, C-terminal domain
View Download 0.297 a.180.1 N-terminal, cytoplasmic domain of anti-sigmaE factor RseA
View Download 0.292 a.4.5 "Winged helix" DNA-binding domain
View Download 0.285 c.2.1 NAD(P)-binding Rossmann-fold domains
View Download 0.281 a.47.2 t-snare proteins
View Download 0.278 a.24.13 Domain of the SRP/SRP receptor G-proteins
View Download 0.277 a.64.2 Bacteriocin AS-48
View Download 0.277 a.24.3 Cytochromes
View Download 0.276 a.23.4 Mitochondrial import receptor subunit Tom20
View Download 0.275 a.24.7 FKBP12-rapamycin-binding domain of FKBP-rapamycin-associated protein (FRAP)
View Download 0.275 a.4.1 Homeodomain-like
View Download 0.272 a.19.1 Fertilization protein
View Download 0.272 d.68.7 R3H domain
View Download 0.271 a.12.1 Kix domain of CBP (creb binding protein)
View Download 0.265 a.159.1 Protein serine/threonine phosphatase 2C, C-terminal domain
View Download 0.263 a.3.1 Cytochrome c
View Download 0.260 b.82.4 Regulatory protein AraC
View Download 0.259 a.46.1 Methionine synthase domain
View Download 0.259 a.77.1 DEATH domain
View Download 0.259 a.27.1 Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases
View Download 0.252 a.24.13 Domain of the SRP/SRP receptor G-proteins
View Download 0.251 a.7.3 Succinate dehydrogenase/fumarate reductase flavoprotein C-terminal domain
View Download 0.250 a.133.1 Phospholipase A2, PLA2
View Download 0.236 d.74.1 Pterin-4a-carbinolamine dehydratase (PCD)/dimerization cofactor of HNF1 (DCoH)
View Download 0.235 a.26.1 4-helical cytokines
View Download 0.234 a.4.5 "Winged helix" DNA-binding domain
View Download 0.231 a.8.2 Plasmid maintenance system epsilon/zeta, antidote epsilon subunit
View Download 0.230 a.4.1 Homeodomain-like
View Download 0.230 f.16.1 Gated mechanosensitive channel
View Download 0.227 a.80.1 DNA polymerase III clamp loader subunits, C-terminal domain
View Download 0.223 a.64.1 Saposin
View Download 0.219 a.4.5 "Winged helix" DNA-binding domain
View Download 0.217 a.163.1 Crustacean CHH/MIH/GIH neurohormone
View Download 0.214 a.2.6 Effector domain of the protein kinase pkn/prk1
View Download 0.212 a.90.1 Transcription factor STAT-4 N-domain
View Download 0.211 a.21.1 HMG-box
View Download 0.208 a.134.1 Fungal elicitin
View Download 0.203 a.4.5 "Winged helix" DNA-binding domain
View Download 0.203 d.74.2 C-terminal domain of arginine repressor
View Download 0.200 c.55.4 Translational machinery components

Predicted Domain #2
Region A:
Residues: [83-340]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 NGEVIEWSKF AYVNYVTNAD YLCNTLIIFN DLKQEFETKA KLVLLISKDL LDPNTSSNVA  60
   61 YISSLLNKIQ AIDEDQVVIK LIDNIVKPKD TTPWNESLTK LLVFNQTEFD RVIYLDNDAI 120
  121 LRSSLDELFF LPNYIKFAAP LTYWFLSNSD LEKSYHETRH REKQPINLQS YTKVLTKRIG 180
  181 KGQMIYNHLP SLPHSLYLNS NNIAQDIISS TSSLSPLFDF QSSKKVGKLK FASNLMVINP 240
  241 SKEAFDEIVN VMLPKILN

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 42.09691
Match: 1ll0A_
Description: Glycogenin
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
UDP-glycosyltransferase activity 6.50620584399191 bayes_pls_golite062009
acetylgalactosaminyltransferase activity 6.18010634203776 bayes_pls_golite062009
polypeptide N-acetylgalactosaminyltransferase activity 6.10775566377356 bayes_pls_golite062009
mannosyltransferase activity 5.57855076532185 bayes_pls_golite062009
transferase activity, transferring glycosyl groups 4.57071306027628 bayes_pls_golite062009
transferase activity, transferring hexosyl groups 4.49413422196176 bayes_pls_golite062009
alpha-1,2-mannosyltransferase activity 3.80392076707564 bayes_pls_golite062009
transferase activity 2.62166586999833 bayes_pls_golite062009
transferase activity, transferring phosphorus-containing groups 2.01768771829228 bayes_pls_golite062009
catalytic activity 1.88676710996045 bayes_pls_golite062009
nucleotidyltransferase activity 1.31793036737589 bayes_pls_golite062009
lactose synthase activity 1.27388044382276 bayes_pls_golite062009
N-acetyllactosamine synthase activity 1.27388044382276 bayes_pls_golite062009
alpha-1,3-mannosylglycoprotein 2-beta-N-acetylglucosaminyltransferase activity 0.734643988700831 bayes_pls_golite062009
glucuronosyltransferase activity 0.36353543999278 bayes_pls_golite062009
uridylyltransferase activity 0.321928989676507 bayes_pls_golite062009
UDP-galactosyltransferase activity 0.10185872015123 bayes_pls_golite062009
galactosyltransferase activity 0.0931461042017721 bayes_pls_golite062009
binding 0.074398891333042 bayes_pls_golite062009
acetylglucosaminyltransferase activity 0.0278258721775009 bayes_pls_golite062009
galactosylgalactosylxylosylprotein 3-beta-glucuronosyltransferase activity 0.00787862255329008 bayes_pls_golite062009

Predicted Domain #3
Region A:
Residues: [341-491]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 KKEKYDMDLI NEEMYNLKKI IYKQFIFFRK VRKLFKPEVL VLPFARYGLL TGSLRNPRHY  60
   61 SIIYNDVLGY KTLDNDGNDI PVGLNDSVAY SKYIHFSDYP LAKPWNYPSM KEFECIVKEE 120
  121 DAEDSKLEHQ ACDLWNSVYA SYIQSREICL V

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below are all of our de novo (Rosetta) predictions for this domain.
Click here to view only most confident match.

Found no structure predictions for this domain.


YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle