YRC Public Data Repository - Protein Structure Prediction

Protein:	RBL2
Organism:	Saccharomyces cerevisiae
Length:	106 amino acids
Reference:	Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for RBL2.

Description	E-value	Query Range	Subject Range
TBCA_ARATH - Tubulin-folding cofactor A OS=Arabidopsis thaliana GN=TFCA PE=1 SV=2	2.0E-24	[6..83]	[7..83]
RBL2 - Protein involved in microtubule morphogenesis, required for protection from excess free beta-tubulin... TBCA_YEAST - Tubulin-specific chaperone A OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=RBL2 PE=1 S...	2.0E-22	[1..106]	[1..106]
TBCA_SCHPO - Tubulin-specific chaperone A OS=Schizosaccharomyces pombe (strain 972 / ATCC 24843) GN=alp31 PE=3 SV... alp31 - tubulin specific chaperone cofactor A	8.0E-20	[6..104]	[8..107]
CG1890-PA - This gene is referred to in FlyBase by the symbol Dmel\CG1890 (CG1890, FBgn0039869). It is a protein...	4.0E-19	[5..106]	[8..105]
gi\|61360418, gi\|... - gi\|61360418\|gb\|AAX41859.1\| tubulin-specific chaperone a [synthetic construct], gi\|61360412\|gb\|AAX418... gi\|114599534, gi... - gi\|114599534\|ref\|XP_001142906.1\| PREDICTED: tubulin-specific chaperone a [Pan troglodytes], gi\|11459... TBCA - tubulin folding cofactor A	7.0E-18	[5..96]	[8..98]
TBCA_MOUSE - Tubulin-specific chaperone A OS=Mus musculus GN=Tbca PE=1 SV=3	1.0E-17	[5..96]	[8..98]
gi\|5852126, gi\|6... - gi\|68128693\|emb\|CAJ08825.1\| tubulin binding cofactor A-like protein [Leishmania major], gi\|5852126\|e... gi\|157874269 - gi\|157874269\|ref\|XP_001685621.1\| tubulin binding cofactor A-like protein [Leishmania major]	1.0E-17	[6..91]	[26..108]
TBCA_BOVIN - Tubulin-specific chaperone A OS=Bos taurus GN=TBCA PE=1 SV=3	3.0E-17	[5..96]	[8..98]
TBCA_RABIT - Tubulin-specific chaperone A (Tubulin-folding cofactor A) (CFA) (TCP1-chaperonin cofactor A) - Oryct...	3.0E-17	[5..96]	[7..97]

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Predicted Domain #1

Region A:
Residues: [1-106]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MAPTQLDIKV KALKRLTKEE GYYQQELKDQ EAHVAKLKED KSVDPYDLKK QEEVLDDTKR  60
   61 LLPTLYEKIR EFKEDLEQFL KTYQGTEDVS DARSAITSAQ ELLDSK

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	370.211549
Match:	1qsdA_
Description:	Tubulin chaperone cofactor A
Matching Structure (courtesy of the PDB):

Predicted functions:

Term	Confidence	Notes
tubulin binding	1.59841692410283	bayes_pls_golite062009
chaperone binding	1.47792074338377	bayes_pls_golite062009
binding	1.45739561719433	bayes_pls_golite062009
protein binding	1.10534436186662	bayes_pls_golite062009
cytoskeletal protein binding	1.05229827202105	bayes_pls_golite062009
beta-tubulin binding	0.19316209765893	bayes_pls_golite062009

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits

Predicted functions: