YRC Public Data Repository - Protein Structure Prediction

Protein:	RPN8
Organism:	Saccharomyces cerevisiae
Length:	338 amino acids
Reference:	Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for RPN8.

Description	E-value	Query Range	Subject Range
RPN8_YEAST - 26S proteasome regulatory subunit RPN8 OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=R... RPN8 - Essential, non-ATPase regulatory subunit of the 26S proteasome; has similarity to the human p40 prot...	0.0	[1..338]	[1..338]
gi\|220958480, gi... - gi\|220958480\|gb\|ACL91783.1\| Mov34-PA [synthetic construct], gi\|220949558\|gb\|ACL87322.1\| Mov34-PA [sy... FBpp0305141, Mov... - The gene Mov34 is referred to in FlyBase by the symbol Dmel\Mov34 (CG3416, FBgn0002787). It is a pro... gi\|194194960, gi... - gi\|195586378\|ref\|XP_002082951.1\| GD11854 [Drosophila simulans], gi\|194194960\|gb\|EDX08536.1\| GD11854 ... gi\|195353107, gi... - gi\|195353107\|ref\|XP_002043047.1\| GM11856 [Drosophila sechellia], gi\|194127135\|gb\|EDW49178.1\| GM11856...	3.0E-99	[4..337]	[7..324]
RPN8_NEUCR - 26S proteasome regulatory subunit rpn-8 OS=Neurospora crassa (strain ATCC 24698 / 74-OR23-1A / CBS 7... RPN8_NEUCR - 26S proteasome regulatory subunit rpn-8 OS=Neurospora crassa GN=rpn-8 PE=3 SV=1	2.0E-97	[1..338]	[9..345]
gi\|2599117 - gi\|2599117\|gb\|AAB84057.1\| proteasome regulatory subunit 12 [Hypocrea jecorina]	1.0E-95	[1..328]	[9..328]
PSMD7_MOUSE - 26S proteasome non-ATPase regulatory subunit 7 OS=Mus musculus GN=Psmd7 PE=1 SV=2	8.0E-86	[3..301]	[4..285]
gi\|17297979 - gi\|17297979\|dbj\|BAB78487.1\| 26S proteasome regulatory particle non-ATPase subunit8 [Oryza sativa Jap...	1.0E-85	[4..303]	[13..295]
PSMD7 - proteasome (prosome, macropain) 26S subunit, non-ATPase, 7 gi\|114663622, gi... - gi\|114663622\|ref\|XP_511103.2\| PREDICTED: proteasome 26S non-ATPase subunit 7 isoform 2 [Pan troglody...	2.0E-85	[3..301]	[4..285]
gi\|7507776 - gi\|7507776\|pir\|\|T16867 probable cytochrome P450 T13C5.1 [similarity] - Caenorhabditis elegans	6.0E-85	[3..301]	[4..285]
PSD7B_ARATH - 26S proteasome non-ATPase regulatory subunit 7 homolog B OS=Arabidopsis thaliana GN=RPN8B PE=1 SV=1	3.0E-84	[4..303]	[13..295]

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Predicted Domain #1

Region A:
Residues: [1-125]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MSLQHEKVTI APLVLLSALD HYERTQTKEN KRCVGVILGD ANSSTIRVTN SFALPFEEDE  60
   61 KNSDVWFLDH NYIENMNEMC KKINAKEKLI GWYHSGPKLR ASDLKINELF KKYTQNNPLL 120
  121 LIVDV

[Run NCBI BLAST on this sequence.]

Detection Method:	Pfam
Confidence:	46.113509
Match:	PF01398
Description:	Mov34/MPN/PAD-1 family

Shown below is our most confident prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #2

Region A:
Residues: [126-338]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 KQQGVGLPTD AYVAIEQVKD DGTSTEKTFL HLPCTIEAEE AEEIGVEHLL RDVRDQAAGG  60
   61 LSIRLTNQLK SLKGLQSKLK DVVEYLDKVI NKELPINHTI LGKLQDVFNL LPNLGTPDDD 120
  121 EIDVENHDRI NISNNLQKAL TVKTNDELMV IYISNLVRSI IAFDDLIENK IQNKKIQEQR 180
  181 VKDKQSKVSD DSESESGDKE ATAPLIQRKN KKN

[Run NCBI BLAST on this sequence.]

Detection Method:

MSA

Shown below is our most confident prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits