YRC Public Data Repository - Protein Structure Prediction

Protein:	ABP140
Organism:	Saccharomyces cerevisiae
Length:	628 amino acids
Reference:	Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for ABP140.

Description	E-value	Query Range	Subject Range
metl-PB - The gene methyltransferase-like is referred to in FlyBase by the symbol Dmel\metl (CG13929, FBgn0035... gi\|220955912, gi... - gi\|220955912\|gb\|ACL90499.1\| metl-PB [synthetic construct], gi\|220946126\|gb\|ACL85606.1\| metl-PB [synt...	0.0	[334..627]	[31..324]
AB140_YEAST - tRNA(Thr) (cytosine(32)-N(3))-methyltransferase OS=Saccharomyces cerevisiae (strain ATCC 204508 / S2... ABP140 - Nonessential protein that binds actin filaments and localizes to actin patches and cables, has simil...	0.0	[1..628]	[1..628]
gi\|7507776 - gi\|7507776\|pir\|\|T16867 probable cytochrome P450 T13C5.1 [similarity] - Caenorhabditis elegans	0.0	[277..628]	[11..362]
METL6_MOUSE - Methyltransferase-like protein 6 OS=Mus musculus GN=Mettl6 PE=2 SV=2	0.0	[363..627]	[10..269]
gi\|10434443 - gi\|10434443\|dbj\|BAB14260.1\| unnamed protein product [Homo sapiens]	1.0E-96	[436..627]	[47..236]
SPBC3H7.11 - actin binding methyltransferase YNVB_SCHPO - Uncharacterized methyltransferase C3H7.11 OS=Schizosaccharomyces pombe (strain 972 / ATCC 24843) GN=...	3.0E-89	[381..626]	[5..247]

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Predicted Domain #1

Region A:
Residues: [1-60]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MGVADLIKKF ESISKEEGDA TVDTNSSSKP LKSNDETKEL HQQESTAVPQ EVDVNEEFEN  60
   61

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	3.0
Match:	2tmaA_
Description:	Tropomyosin
Matching Structure (courtesy of the PDB):

Predicted Domain #2

Region A:
Residues: [61-417]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 EPETINSSRT AEKPLETNLP KPETNEEDEE EGSMSENKIY SKGENADINV NDFQEYKEME  60
   61 NTGAEVLASS VEESDAIQEG VAEETEGIAT PKQKENEKND ESEEESANNA SEPAEEYSQS 120
  121 EEDADIEQSN GKETENAENA SQQANDGSTS TTTSKNKKKK NKKKNKKKRN GNVNTNANVD 180
  181 DSTKTGENDD TTGDTTSSTT SAIQEVNDLE VVDDSCLGID QQHNREHLKA LTQDVKEETL 240
  241 ENIAHEGRGD NTGDQNAVEK SDFEKSDTEG SRIGRDLPFE FGKRNLTEES DVWDHNAWDN 300
  301 VEWGEEQVQQ AEEKIKEQFK HPVPEFDKKL YNENPARYWD IFYKNNKENF FKDRKWL

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	15.522879
Match:	1i84S_
Description:	Heavy meromyosin subfragment
Matching Structure (courtesy of the PDB):

Predicted Domain #3

Region A:
Residues: [418-545]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 QIEFPILYAS TRKDAEPVTI FEIGCGAGNT FFPILKDNEN ENLRIIAADF APRAVELVKN  60
   61 SEQFNPKYGH ATVWDLANPD GNLPDGVEPH SVDIAVMIFV FSALAPNQWD QAMDNLHKIL 120
  121 KPGGKIIF

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	3.221849
Match:	1im8A_
Description:	Hypothetical protein HI0319 (YecO)
Matching Structure (courtesy of the PDB):

Predicted Domain #4

Region A:
Residues: [546-628]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 RDYGAYDLTQ VRFKKNRILE ENFYVRGDGT RVYFFSEEKL REIFTKKYFL ENKIGTDRRL  60
   61 LVNRKRQLKM YRCWVQAVFD VPQ

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	4.221849
Match:	1hnnA_
Description:	Phenylethanolamine N-methyltransferase, PNMTase
Matching Structure (courtesy of the PDB):

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits