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View Structure Prediction Details

Protein: BFR1
Organism: Saccharomyces cerevisiae
Length: 470 amino acids
Reference: Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for BFR1.

Description E-value Query
Range
Subject
Range
MYH4_PIG - Myosin-4 OS=Sus scrofa GN=MYH4 PE=2 SV=1
8.0E-62 [2..469] [915..1404]
gi|7507776 - gi|7507776|pir||T16867 probable cytochrome P450 T13C5.1 [similarity] - Caenorhabditis elegans
5.0E-61 [2..469] [129..618]
gi|179508, gi|10... - sp|P12883|MYH7_HUMAN Myosin heavy chain, cardiac muscle beta isoform (MyHC-beta), gi|4557773|ref|NP...
8.0E-61 [2..469] [913..1402]
MYH4_RABIT - Myosin-4 OS=Oryctolagus cuniculus GN=MYH4 PE=1 SV=1
1.0E-60 [2..469] [916..1405]
MYSS_CYPCA - Myosin heavy chain, fast skeletal muscle OS=Cyprinus carpio PE=2 SV=2
2.0E-60 [2..469] [914..1403]
gi|45383668, gi|... - gi|9800486|gb|AAF99314.1|AF272033_1 fast myosin heavy chain isoform 2 [Gallus gallus], gi|45383668|r...
2.0E-60 [2..469] [921..1410]

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Predicted Domain #1
Region A:
Residues: [1-323]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MSSQQHKFKR PDVSVRDKKL DTLNVQLKKI DTEIGLIRKQ IDQHQVNDTT QQERKKLQDK  60
   61 NKEIIKIQAD LKTRRSNIHD SIKQLDAQIK RKNNQIEEKL GKKAKFSSTA EAKQRINEIE 120
  121 ESIASGDLSL VQEKLLVKEM QSLNKLIKDL VNIEPIRKSV DADKAKINQL KEELNGLNPK 180
  181 DVSNQFEENQ QKLNDIHSKT QGVYDKRQTL FNKRAALYKK RDELYSQIRQ IRADFDNEFK 240
  241 SFRAKLDKER LKREEEQRLS KLLEQKDVDM GKLQEKLTHA KIPAFTYEIG AIENSLLVLD 300
  301 PTYVKPKKNI LPDLSSNALE TKP

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 19.69897
Match: 1i84S_
Description: Heavy meromyosin subfragment
Matching Structure (courtesy of the PDB):

Predicted Domain #2
Region A:
Residues: [324-470]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 ARKVVADDLV LVTPKKDDFV NVAPSKSKKY KKKNQQKNTE NEQPASIFNK VDGKFTLEPT  60
   61 LIATLAELDV TVPINSDDVK ITVEQLKKKH EELLSKQEEQ TKQNIESVEK EIEKLNLDYS 120
  121 NKEQQVKKEL EEKRLKEQEE SEKDKEN

[Run NCBI BLAST on this sequence.]

Detection Method: MSA

Shown below are all of our structure predictions for this domain.
Click here to view only most confident match.

    MCM
Score
GO
Score
GO
Term
SCOP
Match
SCOP Description
View Download 0.584 0.145 budding cell bud growth a.25.1 Ferritin-like
View Download 0.584 0.058 mRNA metabolic process a.25.1 Ferritin-like
View Download 0.596 0.042 budding cell bud growth a.27.1 Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases
View Download 0.572 0.028 budding cell bud growth a.7.1 Spectrin repeat
View Download 0.596 0.017 mRNA metabolic process a.27.1 Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases
View Download 0.469 0.013 budding cell bud growth f.1.1 Colicin
View Download 0.572 0.011 mRNA metabolic process a.7.1 Spectrin repeat
View Download 0.572 0.008 budding cell bud growth a.7.5 Tubulin chaperone cofactor A
View Download 0.469 0.005 mRNA metabolic process f.1.1 Colicin
View Download 0.572 0.003 mRNA metabolic process a.7.5 Tubulin chaperone cofactor A
View Download 0.468 N/A N/A a.7.4 Smac/diablo
View Download 0.467 N/A N/A a.25.1 Ferritin-like
View Download 0.432 N/A N/A a.63.1 Apolipophorin-III
View Download 0.413 N/A N/A d.58.39 Glutamyl tRNA-reductase catalytic, N-terminal domain
View Download 0.413 N/A N/A a.25.1 Ferritin-like
View Download 0.412 N/A N/A a.78.1 Fatty acid responsive transcription factor FadR, C-terminal domain
View Download 0.376 N/A N/A a.1.1 Globin-like
View Download 0.375 N/A N/A a.29.2 Bromodomain
View Download 0.346 N/A N/A a.1.1 Globin-like
View Download 0.336 N/A N/A a.24.1 Apolipoprotein
View Download 0.330 N/A N/A e.20.1 Heat shock protein 70kD (HSP70), C-terminal substrate-binding fragment
View Download 0.327 N/A N/A i.11.1 Computational models partly based on NMR data
View Download 0.324 N/A N/A d.2.1 Lysozyme-like
View Download 0.316 N/A N/A b.82.3 cAMP-binding domain-like
View Download 0.295 N/A N/A f.14.1 Voltage-gated potassium channels
View Download 0.290 N/A N/A a.74.1 Cyclin-like
View Download 0.285 N/A N/A a.7.1 Spectrin repeat
View Download 0.283 N/A N/A a.100.1 6-phosphogluconate dehydrogenase C-terminal domain-like
View Download 0.271 N/A N/A d.129.1 TATA-box binding protein-like
View Download 0.267 N/A N/A a.118.8 TPR-like
View Download 0.263 N/A N/A a.7.5 Tubulin chaperone cofactor A
View Download 0.263 N/A N/A a.29.2 Bromodomain
View Download 0.262 N/A N/A a.24.3 Cytochromes
View Download 0.249 N/A N/A c.95.1 Thiolase-like
View Download 0.244 N/A N/A a.61.1 Retroviral matrix proteins
View Download 0.237 N/A N/A a.5.4 Elongation factor TFIIS domain 2
View Download 0.235 N/A N/A a.25.1 Ferritin-like
View Download 0.217 N/A N/A a.7.1 Spectrin repeat
View Download 0.214 N/A N/A a.26.1 4-helical cytokines
View Download 0.214 N/A N/A a.47.2 t-snare proteins
View Download 0.208 N/A N/A c.51.3 B12-dependend dehydatases associated subunit
View Download 0.203 N/A N/A a.87.1 DBL homology domain (DH-domain)


YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle