YRC Public Data Repository - Protein Structure Prediction

Protein:	SEY1
Organism:	Saccharomyces cerevisiae
Length:	776 amino acids
Reference:	Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for SEY1.

Description	E-value	Query Range	Subject Range
SEY1_YEAST - Protein SEY1 OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=SEY1 PE=1 SV=1 SEY1 - GTPase with a role in ER morphology; interacts physically and genetically with Yop1p and Rtn1p; poss...	0.0	[1..776]	[1..776]
gi\|13702166, gi\|... - gi\|13702166\|dbj\|BAB43823.1\| CaNAG6 [Candida albicans], gi\|13702159\|dbj\|BAB43817.1\| CaNAG6 [Candida a...	0.0	[6..767]	[28..789]
gi\|7507776 - gi\|7507776\|pir\|\|T16867 probable cytochrome P450 T13C5.1 [similarity] - Caenorhabditis elegans	0.0	[7..759]	[27..821]
RHD3_ARATH - Protein ROOT HAIR DEFECTIVE 3 OS=Arabidopsis thaliana GN=RHD3 PE=1 SV=1	0.0	[1..714]	[1..710]
SEY1_ASPFC - Protein sey1 OS=Neosartorya fumigata (strain CEA10 / CBS 144.89 / FGSC A1163) GN=sey1 PE=3 SV=1 SEY1_ASPFU - Protein sey1 OS=Neosartorya fumigata (strain ATCC MYA-4609 / Af293 / CBS 101355 / FGSC A1100) GN=sey... SEY1_ASPFU - Protein sey1 OS=Aspergillus fumigatus GN=sey1 PE=3 SV=1	0.0	[7..765]	[23..831]
SEY1_SCHPO - Protein sey1 OS=Schizosaccharomyces pombe (strain 972 / ATCC 24843) GN=sey1 PE=1 SV=1 SPAC222.14c - GTP binding protein Sey1	0.0	[2..748]	[5..724]
gi\|455407 - gi\|455407\|emb\|CAA50199.1\| unnamed protein product [Entamoeba histolytica]	3.0E-77	[424..725]	[6..302]

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Predicted Domain #1

Region A:
Residues: [1-148]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MADRPAIQLI DEEKEFHQSA LQYFQQCIGN RDVGLDYHVI SVFGSQSSGK STLLNVLFNT  60
   61 NFDTMDAQVK RQQTTKGIWL AHTKQVNTTI EIDNDRPDIF VLDVEGSDGS ERGEDQDFER 120
  121 KAALFAIAVS EVLIVNMWEQ QIGLYQGN

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	2.154902
Match:	1dg3A_
Description:	Interferon-induced guanylate-binding protein 1 (GBP1), C-terminal domain; Interferon-induced guanylate-binding protein 1 (GBP1), N-terminal domain
Matching Structure (courtesy of the PDB):

Predicted Domain #2

Region A:
Residues: [149-283]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 NMALLKTVFE VNLSLFGKND NDHKVLLLFV IRDHVGVTPL SSLSDSVTRE LEKIWTELSK  60
   61 PAGCEGSSLY DYFDLKFVGL AHKLLQEDKF TQDVKKLGDS FVMKGTENYY FKPQYHHRLP 120
  121 LDGWTMYAEN CWDQI

[Run NCBI BLAST on this sequence.]

Detection Method:	ORFEUS
Confidence:	8.39
Match:	1n1bA
Description:	(+)-bornyl diphosphate synthase
Matching Structure (courtesy of the PDB):

Predicted Domain #3

Region A:
Residues: [284-633]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 ERNKDLDLPT QQILVARFKT EEISNEALEE FISKYDESIA PLKGNLGSLT SQLVKLKEEC  60
   61 LTKYDEQASR YARNVYMEKR EALNTKLNSH ISGTINEFLE SLMEKLWDDL KLEVSSRDKA 120
  121 TTSFVESVAA GKSKIEKEFN ESMETFKKLG LLISNEEITC KFSDDIEERI KQLRDAELKA 180
  181 KIGRIKKNLV PELKDHVIHL LSHPSKKVWD DIMNDFESTI KDNISAYQVE KDKYDFKIGL 240
  241 SESENAKIYK NIRILAWRTL DTTVHDYLKI DTIVSILRDR FEDVFRYDAE GSPRLWKTEE 300
  301 EIDGAFRVAK EHALEVFEVL SLAVTSDNVE IIPDVPMAEE ESGEDNEIYR

[Run NCBI BLAST on this sequence.]

Detection Method:	ORFEUS
Confidence:	8.39
Match:	1n1bA
Description:	(+)-bornyl diphosphate synthase
Matching Structure (courtesy of the PDB):

Predicted Domain #4

Region A:
Residues: [634-776]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 DNEGVFHSRR FAHILTELQK ENVLDQFRRQ INITVLDSKR SIITTRTHIP PWIYVLLAVL  60
   61 GWNEFVAVIR NPLFVTLTLI LGATFFVIHK FGLWGPVVNV VQSAVGETRT AIKDKLRQFV 120
  121 VEDHEVKESF EMKDFSKNEQ KEK

[Run NCBI BLAST on this sequence.]

Detection Method:

deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits