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View Structure Prediction Details

Protein: ARP8
Organism: Saccharomyces cerevisiae
Length: 881 amino acids
Reference: Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for ARP8.

Description E-value Query
Range
Subject
Range
ARP8 - Nuclear actin-related protein involved in chromatin remodeling, component of chromatin-remodeling en...
ARP8_YEAST - Actin-like protein ARP8 OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=ARP8 PE=1 SV=1
0.0 [1..881] [1..881]
ACTB_XENLA - Actin, cytoplasmic 1 OS=Xenopus laevis GN=actb PE=2 SV=1
0.0 [375..705] [44..354]
gi|16554294 - gi|16554294|gb|AAK27412.1| actin [Monosiga brevicollis]
0.0 [375..705] [44..354]
gi|157763022 - gi|157763022|ref|XP_001673853.1| Hypothetical protein CBG23091 [Caenorhabditis briggsae AF16]
CRE18004 - RP38795 WBGene00085263 locus:Cre-act-2 status:Confirmed
act-2 - actin status:Confirmed UniProt:P10984 protein_id:CAB04675.1
gi|187021297, gi... - gi|39591934|emb|CAE75154.1| Hypothetical protein CBG23091 [Caenorhabditis briggsae], gi|187021297|em...
0.0 [375..705] [45..355]
gi|194130965, gi... - gi|195340496|ref|XP_002036849.1| GM12447 [Drosophila sechellia], gi|194130965|gb|EDW53008.1| GM12447...
gi|195401955, gi... - gi|195401955|ref|XP_002059576.1| GJ14747 [Drosophila virilis], gi|194147283|gb|EDW62998.1| GJ14747 [...
gi|195432731, gi... - gi|195432731|ref|XP_002064370.1| GK20124 [Drosophila willistoni], gi|194160455|gb|EDW75356.1| GK2012...
gi|195480603, gi... - gi|195480603|ref|XP_002101323.1| Act57B [Drosophila yakuba], gi|194188847|gb|EDX02431.1| Act57B [Dro...
gi|89473786, gi|... - gi|89473786|gb|ABD72705.1| putative actin [Acyrthosiphon pisum], gi|187109134|ref|NP_001119672.1| ac...
gi|195565315, gi... - gi|195565315|ref|XP_002106247.1| GD16764 [Drosophila simulans], gi|194203621|gb|EDX17197.1| GD16764 ...
ACT4_BOMMO - Actin, cytoplasmic A4 OS=Bombyx mori GN=A4 PE=2 SV=1
gi|91088365, gi|... - gi|91088369|ref|XP_976070.1| PREDICTED: similar to Actin-5C isoform 3 [Tribolium castaneum], gi|9108...
gi|220947776, gi... - gi|220957086|gb|ACL91086.1| Act5C-PA [synthetic construct], gi|220947776|gb|ACL86431.1| Act5C-PA [sy...
gi|170048737, gi... - gi|170048737|ref|XP_001870756.1| conserved hypothetical protein [Culex quinquefasciatus], gi|1678707...
gi|190648678, gi... - gi|194889160|ref|XP_001977029.1| GG18797 [Drosophila erecta], gi|190648678|gb|EDV45956.1| GG18797 [D...
gi|193892986, gi... - gi|195046398|ref|XP_001992145.1| GH24372 [Drosophila grimshawi], gi|193892986|gb|EDV91852.1| GH24372...
gi|125981707|ref... - GA17886-PA [Drosophila pseudoobscura], GA17886 [Drosophila pseudoobscura pseudoobscura]
gi|193907820, gi... - gi|195129856|ref|XP_002009370.1| GI15312 [Drosophila mojavensis], gi|193907820|gb|EDW06687.1| GI1531...
gi|195166956, gi... - gi|195166956|ref|XP_002024300.1| GL14888 [Drosophila persimilis], gi|194107673|gb|EDW29716.1| GL1488...
FBpp0311818, Act... - The gene Actin 5C is referred to in FlyBase by the symbol Dmel\Act5C (CG4027, FBgn0000042). It is a ...
ACT5C_ANOGA - Actin-5C OS=Anopheles gambiae GN=Act5C PE=2 SV=1
gi|54643168, gi|... - gi|54643168|gb|EAL31912.1| GA17886 [Drosophila pseudoobscura pseudoobscura], gi|125981707|ref|XP_001...
gi|157128681, gi... - gi|157128681|ref|XP_001655176.1| actin [Aedes aegypti], gi|157128679|ref|XP_001655175.1| actin [Aede...
gi|52630919 - gi|52630919|gb|AAU84923.1| putative actin [Toxoptera citricida]
ACT3B_HELAM - Actin-A3b, cytoplasmic OS=Helicoverpa armigera GN=actA3b PE=2 SV=1
gi|118780938, gi... - gi|58381342|ref|XP_311177.2| ENSANGP00000019055 [Anopheles gambiae str. PEST], gi|55242984|gb|EAA068...
0.0 [375..705] [45..355]
gi|16359158 - gi|16359158|gb|AAH16045.1| Actin, beta [Homo sapiens]
0.0 [375..705] [44..354]
gi|49868, gi|387083 - gi|49868|emb|CAA27396.1| put. beta-actin (aa 27-375) [Mus musculus], gi|387083|gb|AAA37144.1| cytopl...
0.0 [375..705] [18..328]

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Predicted Domain #1
Region A:
Residues: [1-108]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MSQEEAESSI IYEEPIDIPL EDDDDEDELE EENSVPLSSQ ADQENAENES DDSVDNVVGS  60
   61 ETPRSVTGLS VDPRDVADEE DEDEEGEDED EDEDDNDVDN EDENDNDN

[Run NCBI BLAST on this sequence.]

Detection Method: MSA

Shown below are all of our structure predictions for this domain.
Click here to view only most confident match.

    MCM
Score
GO
Score
GO
Term
SCOP
Match
SCOP Description
View Download 0.292 0.001 nucleus a.77.1 DEATH domain

Predicted Domain #2
Region A:
Residues: [109-309]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 ANENENELGS SRDKRAPPAV QTSKRYKKYP KLDPAKAPPG KKVPLHLLEK RRLGRIKAAE  60
   61 EFAKTLKKIG IEKVETTTLP ATGLFQPLML INQKNYSSDY LKKDDQIFAL RDRKFLRNNN 120
  121 TSQISSTNTP DVIDLKSLPH SEASAAPLND EIDLNDPTAT IVIHPGSNSI KIGFPKDDHP 180
  181 VVVPNCVAVP KKWLDLENSE H

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below are all of our de novo (Rosetta) predictions for this domain.
Click here to view only most confident match.

Found no structure predictions for this domain.

Predicted Domain #3
Region A:
Residues: [310-484]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 VENVCLQREQ SEEFNNIKSE MEKNFRERMR YYKRKVPGNA HEQVVSFNEN SKPEIISEKN  60
   61 DPSPIEWIFD DSKLYYGSDA LRCVDEKFVI RKPFRGGSFN VKSPYYKSLA ELISDVTKLL 120
  121 EHALNSETLN VKPTKFNQYK VVLVIPDIFK KSHVETFIRV LLTELQFQAV AIIQE

[Run NCBI BLAST on this sequence.]

Region B:
Residues: [690-705]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 ENYGNTLKEN FAPLEK

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 1023.9794
Match: 2btfA_
Description: Actin
Matching Structure (courtesy of the PDB):

Predicted Domain #4
Region A:
Residues: [485-689]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 SLATCYGAGI STSTCVVNIG AAETRIACVD EGTVLEHSAI TLDYGGDDIT RLFALFLLQS  60
   61 DFPLQDWKID SKHGWLLAER LKKNFTTFQD ADVAVQLYNF MNRSPNQPTE KYEFKLFDEV 120
  121 MLAPLALFFP QIFKLIRTSS HKNSSLEFQL PESRDLFTNE LNDWNSLSQF ESKEGNLYCD 180
  181 LNDDLKILNR ILDAHNIIDQ LQDKP

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 1023.9794
Match: 2btfA_
Description: Actin
Matching Structure (courtesy of the PDB):

Predicted Domain #5
Region A:
Residues: [706-881]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 AIVQSIANAS ITADVTRMNS FYSNILIVGG SSKIPALDFI LTDRINIWRP SLLSSASFPQ  60
   61 FYKKLTKEIK DLEGHYVNAP DKTEDENKQI LQAQIKEKIV EELEEQHQNI EHQNGNEHIF 120
  121 PVSIIPPPRD MNPALIIWKG ASVLAQIKLV EELFITNSDW DVHGSRILQY KCIFTY

[Run NCBI BLAST on this sequence.]

Detection Method: ORFEUS
Confidence: 13.93
Match: 1k8kA
Description: Actin-related protein 3, Arp3
Matching Structure (courtesy of the PDB):

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle