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View Structure Prediction Details

Protein: VPS17
Organism: Saccharomyces cerevisiae
Length: 551 amino acids
Reference: Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for VPS17.

Description E-value Query
Range
Subject
Range
gi|173177 - gi|173177|gb|AAA35213.1| VPS17 [Saccharomyces cerevisiae]
0.0 [1..551] [1..551]
VPS17_SCHPO - Vacuolar protein sorting-associated protein 17 OS=Schizosaccharomyces pombe (strain 972 / ATCC 24843...
vps17 - retromer complex subunit Vps17
6.0E-90 [11..503] [8..493]
gi|3152940 - gi|3152940|gb|AAC17182.1| sorting nexin 1 [Homo sapiens]
3.0E-84 [11..466] [31..521]
gi|12248793 - gi|12248793|dbj|BAB20283.1| sorting nexin 1 [Mus musculus]
8.0E-83 [11..466] [31..520]
SNX1_RAT - Sorting nexin-1 OS=Rattus norvegicus GN=Snx1 PE=1 SV=1
4.0E-82 [11..466] [31..521]
gi|18149005 - gi|18149005|dbj|BAB83537.1| sorting nexin 1 [Macaca fascicularis]
9.0E-80 [33..466] [5..473]

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Predicted Domain #1
Region A:
Residues: [1-71]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MTSAVPYDPY DDLDNNPFAE PQEEDSEPAA TTTDGSSSMS EERVGTEQTA ASVQDNGTAN  60
   61 NIQNGLGEEG N

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #2
Region A:
Residues: [72-237]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 ATRSKTSNEH NENQQPSQPS ERVILPERSD EKKKYTLLAK VTGLERFGSA TGKKENPTII  60
   61 FDCSTNLPTF RKQQYKNVKK SYEEFHQLFK YLNVAIQESF VPTLPSAYTT FGINSEEDRM 120
  121 KVTRNFQLWF NRLSQDPLII RNEEVAFFIE SDFNTYTPIN KSKSLA

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 15.221849
Match: 1h6hA_
Description: p40phox NADPH oxidase
Matching Structure (courtesy of the PDB):

Predicted Domain #3
Region A:
Residues: [238-483]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 SGLKRKTLKQ LAPPYDEITE LAEFRPLVKS IYVVSQSLQE KLLRVSRNRK MMVQEENAFG  60
   61 QDFVNLDEHN KLYRRYGKIL TAVGDIDSII ATMDMATLYD GLEWIVRDAY AVKEALTNRH 120
  121 FIMRNLVQAQ QNSKAKQEQA RRFRSRRDIN PMKIDEALRQ LKAAAKNEQV LTLKLQRITS 180
  181 NMIIERKQWI SWYEEWIRSS IKEFTLRKIE YERKKLTLLE RVRSDIRKAD ENGGLSRLGR 240
  241 HAVSNN

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 2.221849
Match: 1i84S_
Description: Heavy meromyosin subfragment
Matching Structure (courtesy of the PDB):

Predicted Domain #4
Region A:
Residues: [484-551]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 NSDTSQTLKG DSWTGESNRK SQIPINKIAH TEFDDELFTE DDGYNSQDSD TTSLNARHAA  60
   61 SLLGMSTK

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.


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