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View Structure Prediction Details

Protein: MSA1
Organism: Saccharomyces cerevisiae
Length: 629 amino acids
Reference: Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for MSA1.

Description E-value Query
Range
Subject
Range
MSA1_YEAST - G1-specific transcription factors activator MSA1 OS=Saccharomyces cerevisiae (strain ATCC 204508 / S...
MSA1 - Activator of G1-specific transcription factors, MBF and SBF; involved in regulation of the timing of...
0.0 [1..629] [1..629]

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Predicted Domain #1
Region A:
Residues: [1-547]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MDKSMIKKRG RPPITKDYPN PLQSPMAHSS MQVQKQGPHS FAKPLMKVGQ SSPSPNKRRL  60
   61 SIDHHHNLAA TTRKGRYRGV LLSTPTKKSS TNGSTPISTP SSNDSYNNTV FSETRKTFLQ 120
  121 SSPPIMTSSP AFQKKNDYMF PSQEQFKLSL TITESGKAVI AGSLPFSPSS KSSHLMNNNN 180
  181 KKIMQNEKIH KGSKKNAPKF EKRRILSLLK QMKNEKYCDT DTLPEAPPAK PSRSDIIDTE 240
  241 LPTIIETSAS PIGSARNNNI LLSQPPQSPP SSAQLKPPST PKSSLQFRMG FTPNVALNSV 300
  301 SLSDTISKST NAVGASNNNN QNGNSISNIA DANTLLTLTN SPGVFLSPRN KMLPKSTTAS 360
  361 NEQQQEFVFK FSSGDPLLLT DDADGNWPEM LFNVSNTPRR QKCFNTPPSW INFGSPGLFS 420
  421 PPRSSNVMVN GTTVATASDS GNVHRQLQAQ LEAQVQVQSQ SNSPTQRQQQ QRQFQIPPPH 480
  481 INMNSSPPQI NIASPPHQSM SRVSSIYFNK EKTTTGVANM LGNTKSENLQ PPANLFTAAH 540
  541 GPSTPRN

[Run NCBI BLAST on this sequence.]

Detection Method: ORFEUS
Confidence: 9.7
Match: 1ivoA
Description: EGF receptor extracellular domain; EGF receptor Cys-rich domains
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
binding 2.99921478264464 bayes_pls_golite062009
nucleic acid binding 2.0106414707696 bayes_pls_golite062009
protein binding 1.84406396813419 bayes_pls_golite062009
growth factor binding 1.34776702960536 bayes_pls_golite062009
insulin-like growth factor binding 0.575677181912068 bayes_pls_golite062009
catalytic activity 0.286333564590773 bayes_pls_golite062009

Predicted Domain #2
Region A:
Residues: [548-629]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 QEFQLPTLIE CTPLIQQTMN GSLGTKYIPG TSISNSATPN LHGFPVGTGK APSSFDDSLK  60
   61 QNPYSNKQDD ARTALKRLID DQ

[Run NCBI BLAST on this sequence.]

Detection Method: ORFEUS
Confidence: 7.37
Match: 1m6bA
Description: Receptor protein-tyrosine kinase Erbb-3 extracellular domain; Receptor protein-tyrosine kinase Erbb-3 Cys-rich domains
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
binding 2.99921478264464 bayes_pls_golite062009
nucleic acid binding 2.0106414707696 bayes_pls_golite062009
protein binding 1.84406396813419 bayes_pls_golite062009
growth factor binding 1.34776702960536 bayes_pls_golite062009
insulin-like growth factor binding 0.575677181912068 bayes_pls_golite062009
catalytic activity 0.286333564590773 bayes_pls_golite062009

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle