YRC Public Data Repository - Protein Structure Prediction

Protein:	CKB2
Organism:	Saccharomyces cerevisiae
Length:	258 amino acids
Reference:	Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for CKB2.

Description	E-value	Query Range	Subject Range
tr\|G3HZG2\|G3HZG2... - Casein kinase II subunit beta OS=Cricetulus griseus GN=H671_1g2786 PE=3 SV=1 gi\|53734598 - gb\|AAH83993.1\| Unknown (protein for MGC:98116) [Xenopus laevis] CSK2B_RAT - Casein kinase II subunit beta OS=Rattus norvegicus GN=Csnk2b PE=1 SV=1 CSNK2B - casein kinase 2, beta polypeptide CSK2B_PIG - Casein kinase II subunit beta OS=Sus scrofa GN=CSNK2B PE=2 SV=1 CSK2B_RABIT - Casein kinase II subunit beta OS=Oryctolagus cuniculus GN=CSNK2B PE=2 SV=1 gi\|213688918, gi... - gi\|215983072\|ref\|NP_001135983.1\| casein kinase 2, beta polypeptide [Ovis aries], gi\|213688918\|gb\|ACJ... CSK2B_MOUSE - Casein kinase II subunit beta OS=Mus musculus GN=Csnk2b PE=1 SV=1 gi\|109070472 - gi\|109070472\|ref\|XP_001112478.1\| PREDICTED: similar to casein kinase 2, beta subunit isoform 1 [Maca... CSK2B_CHICK - Casein kinase II subunit beta OS=Gallus gallus GN=CSNK2B PE=2 SV=1 ENSPTRT00000057498 - null tr\|M3W831\|M3W831... - Casein kinase II subunit beta OS=Felis catus GN=CSNK2B PE=3 SV=1 CSK2B_BOVIN - Casein kinase II subunit beta OS=Bos taurus GN=CSNK2B PE=1 SV=1 gi\|194223340 - gi\|194223340\|ref\|XP_001917725.1\| PREDICTED: similar to casein kinase 2, beta polypeptide isoform 1 [...	0.0	[31..243]	[2..213]
CSK2B_XENLA - Casein kinase II subunit beta OS=Xenopus laevis GN=csnk2b PE=1 SV=1 gi\|49899997, gi\|... - gi\|89271289\|emb\|CAJ82633.1\| casein kinase 2, beta subunit [Xenopus tropicalis], gi\|52346076\|ref\|NP_0...	0.0	[31..243]	[2..213]
gi\|181155 - gi\|181155\|gb\|AAA52123.1\| casein kinase II beta subunit [Homo sapiens]	0.0	[31..243]	[2..213]
CSK2B_DANRE - Casein kinase II subunit beta OS=Danio rerio GN=csnk2b PE=2 SV=1 gi\|11280586, gi\|... - gi\|7672353\|gb\|AAF66446.1\|AF133088_1 CK2 beta subunit [Cyprinus carpio], gi\|11280586\|pir\|\|JC7269 prot... gi\|223649430, gi... - gi\|223649430\|gb\|ACN11473.1\| Casein kinase II subunit beta [Salmo salar], gi\|223648390\|gb\|ACN10953.1\|...	0.0	[31..242]	[2..212]
gi\|7507776 - gi\|7507776\|pir\|\|T16867 probable cytochrome P450 T13C5.1 [similarity] - Caenorhabditis elegans	0.0	[35..243]	[2..209]
CKB2 - Beta' regulatory subunit of casein kinase 2, a Ser/Thr protein kinase with roles in cell growth and ... CSK2C_YEAST - Casein kinase II subunit beta' OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=CKB2 PE=1... gi\|151945669 - gi\|151945669\|gb\|EDN63910.1\| protein kinase CK2 beta' subunit [Saccharomyces cerevisiae YJM789] gi\|190407378 - gi\|190407378\|gb\|EDV10645.1\| protein kinase CK2 [Saccharomyces cerevisiae RM11-1a] gi\|207341245 - gi\|207341245\|gb\|EDZ69352.1\| YOR039Wp-like protein [Saccharomyces cerevisiae AWRI1631]	0.0	[1..258]	[1..258]
gi\|218185028 - gi\|218185028\|gb\|EEC67455.1\| hypothetical protein OsI_34680 [Oryza sativa Indica Group] gi\|12597893, gi\|... - gi\|37536920\|ref\|NP_922762.1\| putative casein kinase II beta subunit [Oryza sativa (japonica cultivar...	0.0	[13..226]	[68..280]
gi\|13936998, gi\|... - gi\|74096135\|ref\|NP_001027591.1\| protein kinase Ck2-beta [Ciona intestinalis], gi\|70569061\|dbj\|BAE063...	0.0	[31..243]	[2..213]
CSK2B_ARATH - Casein kinase II subunit beta OS=Arabidopsis thaliana GN=CKB1 PE=1 SV=1	0.0	[4..224]	[57..286]

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Predicted Domain #1

Region A:
Residues: [1-41]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MGSRSENVGT VTREGSRVEQ DDVLMDDDSD SSEYVDMWID L

[Run NCBI BLAST on this sequence.]

Region B:
Residues: [55-110]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 DPEYITDRFN LMNLQKTVSK FSYVVQYIVD DLDDSILENM THARLEQLES DSRKLY

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	630.0
Match:	1jwhC_
Description:	Casein kinase II beta subunit
Matching Structure (courtesy of the PDB):

Predicted functions:

Term	Confidence	Notes
protein kinase regulator activity	4.14878012076359	bayes_pls_golite062009
kinase regulator activity	4.09603095102334	bayes_pls_golite062009
enzyme regulator activity	2.91779610785511	bayes_pls_golite062009
phosphotransferase activity, alcohol group as acceptor	2.79245883940915	bayes_pls_golite062009
protein kinase activity	2.75473427458132	bayes_pls_golite062009
kinase activity	2.66515798949431	bayes_pls_golite062009
transferase activity, transferring phosphorus-containing groups	2.39333807060713	bayes_pls_golite062009
protein serine/threonine kinase activity	1.99491617326192	bayes_pls_golite062009
binding	1.85951177140712	bayes_pls_golite062009
transferase activity	1.77218599619559	bayes_pls_golite062009
protein binding	1.4657010373022	bayes_pls_golite062009
catalytic activity	0.2012862421225	bayes_pls_golite062009

Predicted Domain #2

Region A:
Residues: [42-54]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 FLGRKGHEYF CDV

[Run NCBI BLAST on this sequence.]

Region B:
Residues: [111-258]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 GLIHARYIIT IKGLQKMYAK YKEADFGRCP RVYCNLQQLL PVGLHDIPGI DCVKLYCPSC  60
   61 EDLYIPKSSR HSSIDGAYFG TSFPGMFLQA FPDMVPKHPT KRYVPKIFGF ELHKQAQLTR 120
  121 WQELQRLKLV EKLESKDVDL TKSGGFKT

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	630.0
Match:	1jwhC_
Description:	Casein kinase II beta subunit
Matching Structure (courtesy of the PDB):

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits

Predicted functions: