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View Structure Prediction Details

Protein: STI1
Organism: Saccharomyces cerevisiae
Length: 589 amino acids
Reference: Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for STI1.

Description E-value Query
Range
Subject
Range
STI1 - Hsp90 cochaperone, interacts with the Ssa group of the cytosolic Hsp70 chaperones; activates the ATP...
STI1_YEAST - Heat shock protein STI1 OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=STI1 PE=1 SV=1
6.0E-93 [1..589] [1..589]
gi|13775066 - gi|13775066|gb|AAK39123.1|AF363030_1 UDP-N-acetylglucosaminyltransferase [Mus musculus]
2.0E-87 [43..533] [24..501]
OGT1_RAT - UDP-N-acetylglucosamine--peptide N-acetylglucosaminyltransferase 110 kDa subunit OS=Rattus norvegicu...
3.0E-87 [39..533] [10..491]
OGT - O-linked N-acetylglucosamine (GlcNAc) transferase (UDP-N-acetylglucosamine:polypeptide-N-acetylgluco...
gi|123993895, gi... - gi|224487755|dbj|BAH24112.1| O-linked N-acetylglucosamine (GlcNAc) transferase [synthetic construct]...
5.0E-87 [39..508] [10..463]
HSOP1_ARATH - Hsp70-Hsp90 organizing protein 1 OS=Arabidopsis thaliana GN=HOP1 PE=2 SV=1
2.0E-86 [5..586] [2..570]
gi|5052534 - gi|5052534|gb|AAD38597.1|AF145622_1 BcDNA.GH04245 [Drosophila melanogaster]
5.0E-86 [37..508] [47..502]
ogt-1 - status:Confirmed UniProt:O18158 protein_id:AAA62535.2
2.0E-84 [10..496] [130..599]

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Predicted Domain #1
Region A:
Residues: [1-147]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MSLTADEYKQ QGNAAFTAKD YDKAIELFTK AIEVSETPNH VLYSNRSACY TSLKKFSDAL  60
   61 NDANECVKIN PSWSKGYNRL GAAHLGLGDL DEAESNYKKA LELDASNKAA KEGLDQVHRT 120
  121 QQARQAQPDL GLTQLFADPN LIENLKK

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 138.07631
Match: 1elwA_
Description: Hop
Matching Structure (courtesy of the PDB):

Predicted Domain #2
Region A:
Residues: [148-224]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 NPKTSEMMKD PQLVAKLIGY KQNPQAIGQD LFTDPRLMTI MATLMGVDLN MDDINQSNSM  60
   61 PKEPETSKST EQKKDAE

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #3
Region A:
Residues: [225-341]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 PQSDSTTSKE NSSKAPQKEE SKESEPMEVD EDDSKIEADK EKAEGNKFYK ARQFDEAIEH  60
   61 YNKAWELHKD ITYLNNRAAA EYEKGEYETA ISTLNDAVEQ GREMRADYKV ISKSFAR

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 226.9794
Match: 1elrA_
Description: Hop
Matching Structure (courtesy of the PDB):

Predicted Domain #4
Region A:
Residues: [342-391]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 IGNAYHKLGD LKKTIEYYQK SLTEHRTADI LTKLRNAEKE LKKAEAEAYV 

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 226.9794
Match: 1elrA_
Description: Hop
Matching Structure (courtesy of the PDB):

Predicted Domain #5
Region A:
Residues: [392-589]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 NPEKAEEARL EGKEYFTKSD WPNAVKAYTE MIKRAPEDAR GYSNRAAALA KLMSFPEAIA  60
   61 DCNKAIEKDP NFVRAYIRKA TAQIAVKEYA SALETLDAAR TKDAEVNNGS SAREIDQLYY 120
  121 KASQQRFQPG TSNETPEETY QRAMKDPEVA AIMQDPVMQS ILQQAQQNPA ALQEHMKNPE 180
  181 VFKKIQTLIA AGIIRTGR

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 118.679424
Match: 1a17__
Description: Protein phosphatase 5
Matching Structure (courtesy of the PDB):

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle