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View Structure Prediction Details

Protein: STI1
Organism: Saccharomyces cerevisiae
Length: 589 amino acids
Reference: Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for STI1.

Description E-value Query
Range
Subject
Range
STI1 - Hsp90 cochaperone, interacts with the Ssa group of the cytosolic Hsp70 chaperones; activates the ATP...
STI1_YEAST - Heat shock protein STI1 OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=STI1 PE=1 SV=1
6.0E-93 [1..589] [1..589]
gi|13775066 - gi|13775066|gb|AAK39123.1|AF363030_1 UDP-N-acetylglucosaminyltransferase [Mus musculus]
2.0E-87 [43..533] [24..501]
OGT1_RAT - UDP-N-acetylglucosamine--peptide N-acetylglucosaminyltransferase 110 kDa subunit OS=Rattus norvegicu...
3.0E-87 [39..533] [10..491]
OGT - O-linked N-acetylglucosamine (GlcNAc) transferase (UDP-N-acetylglucosamine:polypeptide-N-acetylgluco...
gi|123993895, gi... - gi|224487755|dbj|BAH24112.1| O-linked N-acetylglucosamine (GlcNAc) transferase [synthetic construct]...
5.0E-87 [39..508] [10..463]
HSOP1_ARATH - Hsp70-Hsp90 organizing protein 1 OS=Arabidopsis thaliana GN=HOP1 PE=2 SV=1
2.0E-86 [5..586] [2..570]
gi|5052534 - gi|5052534|gb|AAD38597.1|AF145622_1 BcDNA.GH04245 [Drosophila melanogaster]
5.0E-86 [37..508] [47..502]
ogt-1 - status:Confirmed UniProt:O18158 protein_id:AAA62535.2
2.0E-84 [10..496] [130..599]

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Predicted Domain #1
Region A:
Residues: [1-147]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MSLTADEYKQ QGNAAFTAKD YDKAIELFTK AIEVSETPNH VLYSNRSACY TSLKKFSDAL  60
   61 NDANECVKIN PSWSKGYNRL GAAHLGLGDL DEAESNYKKA LELDASNKAA KEGLDQVHRT 120
  121 QQARQAQPDL GLTQLFADPN LIENLKK

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 138.07631
Match: 1elwA_
Description: Hop
Matching Structure (courtesy of the PDB):

Predicted Domain #2
Region A:
Residues: [148-224]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 NPKTSEMMKD PQLVAKLIGY KQNPQAIGQD LFTDPRLMTI MATLMGVDLN MDDINQSNSM  60
   61 PKEPETSKST EQKKDAE

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below are all of our de novo (Rosetta) predictions for this domain.
Click here to view only most confident match.

    MCM
Score
SCOP
Match
SCOP Description
View Download 0.278 c.30.1 PreATP-grasp domain
View Download 0.367 a.64.1 Saposin
View Download 0.257 b.38.1 Sm-like ribonucleoproteins
View Download 0.303 d.68.7 R3H domain
View Download 0.335 a.64.2 Bacteriocin AS-48
View Download 0.244 a.4.6 C-terminal effector domain of the bipartite response regulators
View Download 0.230 a.4.5 "Winged helix" DNA-binding domain

Predicted Domain #3
Region A:
Residues: [225-341]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 PQSDSTTSKE NSSKAPQKEE SKESEPMEVD EDDSKIEADK EKAEGNKFYK ARQFDEAIEH  60
   61 YNKAWELHKD ITYLNNRAAA EYEKGEYETA ISTLNDAVEQ GREMRADYKV ISKSFAR

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 226.9794
Match: 1elrA_
Description: Hop
Matching Structure (courtesy of the PDB):

Predicted Domain #4
Region A:
Residues: [342-391]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 IGNAYHKLGD LKKTIEYYQK SLTEHRTADI LTKLRNAEKE LKKAEAEAYV 

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 226.9794
Match: 1elrA_
Description: Hop
Matching Structure (courtesy of the PDB):

Predicted Domain #5
Region A:
Residues: [392-589]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 NPEKAEEARL EGKEYFTKSD WPNAVKAYTE MIKRAPEDAR GYSNRAAALA KLMSFPEAIA  60
   61 DCNKAIEKDP NFVRAYIRKA TAQIAVKEYA SALETLDAAR TKDAEVNNGS SAREIDQLYY 120
  121 KASQQRFQPG TSNETPEETY QRAMKDPEVA AIMQDPVMQS ILQQAQQNPA ALQEHMKNPE 180
  181 VFKKIQTLIA AGIIRTGR

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 118.679424
Match: 1a17__
Description: Protein phosphatase 5
Matching Structure (courtesy of the PDB):

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle