YRC Public Data Repository - Protein Structure Prediction

Protein:	TRM11
Organism:	Saccharomyces cerevisiae
Length:	433 amino acids
Reference:	Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for TRM11.

Description	E-value	Query Range	Subject Range
TRM11_MOUSE - tRNA (guanine(10)-N2)-methyltransferase homolog OS=Mus musculus GN=Trmt11 PE=1 SV=1	5.0E-79	[1..430]	[7..445]
gi\|151945511 - gi\|151945511\|gb\|EDN63752.1\| N2-monomethylguanosine-specific tRNA methyltransferase [Saccharomyces ce... gi\|207341461 - gi\|207341461\|gb\|EDZ69512.1\| YOL124Cp-like protein [Saccharomyces cerevisiae AWRI1631] TRM11_YEAST - tRNA (guanine(10)-N2)-methyltransferase OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=... TRM11 - Catalytic subunit of an adoMet-dependent tRNA methyltransferase complex (Trm11p-Trm112p), required f...	7.0E-76	[1..433]	[1..433]
gi\|9294300, gi\|1... - gi\|9294300\|dbj\|BAB02202.1\| unnamed protein product [Arabidopsis thaliana], gi\|18404931\|ref\|NP_566792...	7.0E-61	[2..429]	[1..437]
CE29909 - status:Partially_confirmed UniProt:Q9N4H1 protein_id:AAF36002.2	3.0E-57	[1..430]	[1..427]
trm11 - tRNA (guanosine) methyltransferase Trm11 gi\|19113289 - gi\|19113289\|ref\|NP_596497.1\| hypothetical protein SPBC16D10.02 [Schizosaccharomyces pombe 972h-]	8.0E-54	[1..428]	[1..451]
gi\|7767522 - gi\|7767522\|gb\|AAF69138.1\|AF228680_2 HsdM [Lactococcus lactis] gi\|9789463, gi\|3... - gi\|9789463\|gb\|AAF98315.1\|AF243383_16 HsdM [Lactococcus lactis subsp. lactis], gi\|32455489\|ref\|NP_862...	8.0E-45	[1..416]	[1..417]
gi\|57208456, gi\|... - gi\|57208456\|emb\|CAI42396.1\| chromosome 6 open reading frame 75 [Homo sapiens], gi\|119568511\|gb\|EAW48...	2.0E-43	[1..245]	[7..251]
gi\|11279435, gi\|... - gi\|6137148\|gb\|AAF04357.1\| type IC modification subunit [Streptococcus thermophilus], pir\|\|T44803 typ...	1.0E-42	[18..416]	[7..411]

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Predicted Domain #1

Region A:
Residues: [1-112]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MKKYLLYMVQ VHLNFRRAEL ESLADLYNLS IDFSQYDANS PFFIVELEND QQAKDWIKRS  60
   61 ILTRGIYEYW GQGTTLDELH KDIQRQSNFE QDLQLKFKHS TFKFEFECYK GN

[Run NCBI BLAST on this sequence.]

Detection Method:

deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #2

Region A:
Residues: [113-191]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 SKAKRVEQIE TFRYLGFEGK IDMKHPQEVF TVIEEYTPIS ENVGGKTPTR IYFGRQVQMS  60
   61 NRSAMEKYDL KKRPYKGTT

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	8.69897
Match:	1g60A_
Description:	Methyltransferase mboII
Matching Structure (courtesy of the PDB):

Predicted Domain #3

Region A:
Residues: [192-433]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 SFEAELSLVS ANIAQVKPGT IMYDPFAGTG SFLVAGGHFG SLVIGSDIDG RMIRGKGAQV  60
   61 NISANFKKYG ESSQFLDVLT MDFTNNALRN NLVIDTILCD PPYGIRESIK VLGAKDPERF 120
  121 LGKEDMEIDG EKAYLRRDYI PTKKPYALDS LLDDLLQYSS ERLPIGGRLA FWMPTANDAN 180
  181 IETIVPMHEN LELKYNCVQE FNKWSRRLLV YINRGSTFNG SSNHGIKRSK DNFRERYFNN 240
  241 FN

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	22.0
Match:	2admA_
Description:	DNA methylase TaqI
Matching Structure (courtesy of the PDB):

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits