| Protein: | IRA2 |
| Organism: | Saccharomyces cerevisiae |
| Length: | 3079 amino acids |
| Reference: | Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076 |
No multiple sequence alignment data found for IRA2.
|
Region A: Residues: [1-1260] |
1 11 21 31 41 51
| | | | | |
1 MSQPTKNKKK EHGTDSKSSR MTRTLVNHIL FERILPILPV ESNLSTYSEV EEYSSFISCR 60
61 SVLINVTVSR DANAMVEGTL ELIESLLQGH EIISDKGSSD VIESILIILR LLSDALEYNW 120
121 QNQESLHYND ISTHVEHDQE QKYRPKLNSI LPDYSSTHSN GNKHFFHQSK PQALIPELAS 180
181 KLLESCAKLK FNTRTLQILQ NMISHVHGNI LTTLSSSILP RHKSYLTRHN HPSHCKMIDS 240
241 TLGHILRFVA ASNPSEYFEF IRKSVQVPVT QTHTHSHSHS HSLPSSVYNS IVPHFDLFSF 300
301 IYLSKHNFKK YLELIKNLSV TLRKTIYHCL LLHYSAKAIM FWIMARPAEY YELFNLLKDN 360
361 NNEHSKSLNT LNHTLFEEIH STFNVNSMIT TNQNAHQGSS SPSSSSPSSP PSSSSSDNNN 420
421 QNIIAKSLSR QLSHHQSYIQ QQSERKLHSS WTTNSQSSTS LSSSTSNSTT TDFSTHTQPG 480
481 EYDPSLPDTP TMSNITISAS SLLSQTPTPT TQLQQRLNSA AAAAAAAASP SNSTPTGYTA 540
541 EQQSRASYDA HKTGHTGKDY DEHFLSVTRL DNVLELYTHF DDTEVLPHTS VLKFLTTLTM 600
601 FDIDLFNELN ATSFKYIPDC TMHRPKERTS SFNNTAHETG SEKTSGIKHI TQGLKKLTSL 660
661 PSSTKKTVKF VKMLLRNLNG NQAVSDVALL DTMRALLSFF TMTSAVFLVD RNLPSVLFAK 720
721 RLIPIMGTNL SVGQDWNSKI NNSLMVCLKK NSTTFVQLQL IFFSSAIQFD HELLLARLSI 780
781 DTMANNLNMQ KLCLYTEGFR IFFDIPSKKE LRKAIAVKIS KFFKTLFSII ADILLQEFPY 840
841 FDEQITDIVA SILDGTIINE YGTKKHFKGS SPSLCSTTRS RSGSTSQSSM TPVSPLGLDT 900
901 DICPMNTLSL VGSSTSRNSD NVNSLNSSPK NLSSDPYLSH LVAPRARHAL GGPSSIIRNK 960
961 IPTTLTSPPG TEKSSPVQRP QTESISATPM AITNSTPLSS AAFGIRSPLQ KIRTRRYSDE1020
1021 SLGKFMKSTN NYIQEHLIPK DLNEATLQDA RRIMINIFSI FKRPNSYFII PHNINSNLQW1080
1081 VSQDFRNIMK PIFVAIVSPD VDLQNTAQSF MDTLLSNVIT YGESDENISI EGYHLLCSYT1140
1141 VTLFAMGLFD LKINNEKRQI LLDITVKFMK VRSHLAGIAE ASHHMEYISD SEKLTFPLIM1200
1201 GTVGRALFVS LYSSQQKIEK TLKIAYTEYL SAINFHERNI DDADKTWVHN IEFVEAMCHD1260
1261
|
| Detection Method: |  |
Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.
Found no confident structure predictions for this domain.
|
Region A: Residues: [1261-1559] |
1 11 21 31 41 51
| | | | | |
1 NYTTSGSIAF QRRTRNNILR FATIPNAILL DSMRMIYKKW HTYTHSKSLE KQERNDFRNF 60
61 AGILASLSGI LFINKKILQE MYPYLLDTVS ELKKNIDSFI SKQCQWLNYP DLLTRENSRD 120
121 ILSVELHPLS FNLLFNNLRL KLKELACSDL SIPENESSYV LLEQIIKMLR TILGRDDDNY 180
181 VMMLFSTEIV DLIDLLTDEI KKIPAYCPKY LKAIIQMTKM FSALQHSEVN LGVKNHFHVK 240
241 NKWLRQITDW FQVSIAREYD FENLSKPLKE MDLVKRDMDI LYIDTAIEAS TAIAYLTRH
|
| Detection Method: | |
Shown below is our most confident prediction for this domain.
Click here to view all matches.
Found no confident structure predictions for this domain.
|
Region A: Residues: [1560-1665] |
1 11 21 31 41 51
| | | | | |
1 TFLEIPPAAS DPELSRSRSV IFGFYFNILM KGLEKSSDRD NYPVFLRHKM SVLNDNVILS 60
61 LTNLSNTNVD ASLQFTLPMG YSGNRNIRNA FLEVFINIVT NYRTYT
|
| Detection Method: | |
Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.
Found no confident structure predictions for this domain.
|
Region A: Residues: [1666-1719] |
1 11 21 31 41 51
| | | | | |
1 AKTDLGKLEA ADKFLRYTIE HPQLSSFGAA VCPASDIDAY AAGLINAFET RNAT
|
|
Region B: Residues: [1935-2001] |
1 11 21 31 41 51
| | | | | |
1 TDPTPIAFDY QFLHSFVYLY GLEVRRNVLN EAKHDDGDID GDDFYKTTFL LIDDVLGQLG 60
61 QPKMEFS
|
| Detection Method: | |
| Confidence: | 312.457575 |
| Match: | 1nf1A |
| Description: | GAP related domain of neurofibromin |
Matching Structure (courtesy of the PDB): |
|
|
Region A: Residues: [1720-1934] |
1 11 21 31 41 51
| | | | | |
1 HIVVAQLIKN EIEKSSRPTD ILRRNSCATR SLSMLARSKG NEYLIRTLQP LLKKIIQNRD 60
61 FFEIEKLKPE DSDAERQIEL FVKYMNELLE SISNSVSYFP PPLFYICQNI YKVACEKFPD 120
121 HAIIAAGSFV FLRFFCPALV SPDSENIIDI SHLSEKRTFI SLAKVIQNIA NGSENFSRWP 180
181 ALCSQKDFLK ECSDRIFRFL AELCRTDRTI DIQVR
|
| Detection Method: | |
| Confidence: | 312.457575 |
| Match: | 1nf1A |
| Description: | GAP related domain of neurofibromin |
| Matching Structure (courtesy of the PDB): |
|
|
Region A: Residues: [2002-2530] |
1 11 21 31 41 51
| | | | | |
1 NEIPIYIREH MDDYPELYEF MNRHAFRNIE TSTAYSPSVH ESTSSEGIPI ITLTMSNFSD 60
61 RHVDIDTVAY KFLQIYARIW TTKHCLIIDC TEFDEGGLDM RKFISLVMGL LPEVAPKNCI 120
121 GCYYFNVNET FMDNYGKCLD KDNVYVSSKI PHYFINSNSD EGLMKSVGIT GQGLKVLQDI 180
181 RVSLHDITLY DEKRNRFTPV SLKIGDIYFQ VLHETPRQYK IRDMGTLFDV KFNDVYEISR 240
241 IFEVHVSSIT GVAAEFTVTF QDERRLIFSS PKYLEIVKMF YYAQIRLESE YEMDNNSSTS 300
301 SPNSNNKDKQ QKERTKLLCH LLLVSLIGLF DESKKMKNSS YNLIAATEAS FGLNFGSHFH 360
361 RSPEVYVPED TTTFLGVIGK SLAESNPELT AYMFIYVLEA LKNNVIPHVY IPHTICGLSY 420
421 WIPNLYQHVY LADDEEGPEN ISHIFRILIR LSVRETDFKA VYMQYVWLLL LDDGRLTDII 480
481 VDEVINHALE RDSENRDWKK TISLLTVLPT TEVANNIIQK ILAKIRSFL
|
| Detection Method: | |
Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.
Found no confident structure predictions for this domain.
|
Region A: Residues: [2531-2877] |
1 11 21 31 41 51
| | | | | |
1 PSLKLEAMTQ SWSELTILVK ISIHVFFETS LLVQMYLPEI LFIVSLLIDV GPRELRSSLH 60
61 QLLMNVCHSL AINSALPQDH RNNLDEISDI FAHQKVKFMF GFSEDKGRIL QIFSASSFAS 120
121 KFNILDFFIN NILLLMEYSS TYEANVWKTR YKKYVLESVF TSNSFLSARS IMIVGIMGKS 180
181 YITEGLCKAM LIETMKVIAE PKITDEHLFL AISHIFTYSK IVEGLDPNLD LMKHLFWFST 240
241 LFLESRHPII FEGALLFVSN CIRRLYMAQF ENESETSLIS TLLKGRKFAH TFLSKIENLS 300
301 GIVWNEDNFT HILIFIINKG LSNPFIKSTA FDFLKMMFRN SYFEHQI
|
| Detection Method: | |
Shown below is our most confident prediction for this domain.
Click here to view all matches.
Found no confident structure predictions for this domain.
|
Region A: Residues: [2878-3079] |
1 11 21 31 41 51
| | | | | |
1 NQKSDHYLCY MFLLYFVLNC NQFEELLGDV DFEGEMVNIE NKNTIPKILL EWLSSDNENA 60
61 NITLYQGAIL FKCSVTDEPS RFRFALIIRH LLTKKPICAL RFYSVIRNEI RKISAFEQNS 120
121 DCVPLAFDIL NLLVTHSESN SLEKLHEESI ERLTKRGLSI VTSSGIFAKN SDMMIPLDVK 180
181 PEDIYERKRI MTMILSRMSC SA
|
| Detection Method: | |
Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.
Found no confident structure predictions for this domain.
