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View Structure Prediction Details

Protein: GAL11
Organism: Saccharomyces cerevisiae
Length: 1081 amino acids
Reference: Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for GAL11.

Description E-value Query
Range
Subject
Range
GAL11 - Subunit of the RNA polymerase II mediator complex; associates with core polymerase subunits to form ...
MED15_YEAST - Mediator of RNA polymerase II transcription subunit 15 OS=Saccharomyces cerevisiae (strain ATCC 2045...
0.0 [1..1081] [1..1081]
PLEC1 - plectin 1, intermediate filament binding protein 500kDa
2.0E-74 [8..696] [1790..2487]
PLEC_RAT - Plectin OS=Rattus norvegicus GN=Plec PE=1 SV=2
4.0E-67 [3..696] [1788..2490]
PLEC_CRIGR - Plectin (Fragment) OS=Cricetulus griseus GN=PLEC PE=1 SV=1
4.0E-66 [8..696] [1585..2276]
gi|7507776 - gi|7507776|pir||T16867 probable cytochrome P450 T13C5.1 [similarity] - Caenorhabditis elegans
7.0E-65 [4..694] [715..1420]
gi|13094681 - gi|13094681|gb|AAK11965.1|AF273685_1 ribosome receptor isoform mRRp41 [Mus musculus]
4.0E-56 [7..500] [142..626]

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Predicted Domain #1
Region A:
Residues: [1-296]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MSAAPVQDKD TLSNAERAKN VNGLLQVLMD INTLNGGSSD TADKIRIHAK NFEAALFAKS  60
   61 SSKKEYMDSM NEKVAVMRNT YNTRKNAVTA AAANNNIKPV EQHHINNLKN SGNSANNMNV 120
  121 NMNLNPQMFL NQQAQARQQV AQQLRNQQQQ QQQQQQQQRR QLTPQQQQLV NQMKVAPIPK 180
  181 QLLQRIPNIP PNINTWQQVT ALAQQKLLTP QDMEAAKEVY KIHQQLLFKA RLQQQQAQAQ 240
  241 AQANNNNNGL PQNGNINNNI NIPQQQQMQP PNSSANNNPL QQQSSQNTVP NVLNQI

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 4.39794
Match: 1i84S_
Description: Heavy meromyosin subfragment
Matching Structure (courtesy of the PDB):

Predicted Domain #2
Region A:
Residues: [297-507]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 NQIFSPEEQR SLLQEAIETC KNFEKTQLGS TMTEPVKQSF IRKYINQKAL RKIQALRDVK  60
   61 NNNNANNNGS NLQRAQNVPM NIIQQQQQQN TNNNDTIATS ATPNAAAFSQ QQNASSKLYQ 120
  121 MQQQQQAQAQ AQAQAQAQAQ AQAQAQAAQA AQAQAQAQAQ AQAQAQAQAQ AQAQAQAQAQ 180
  181 AQAQAHAQHQ PSQQPQQAQQ QPNPLHGLTP T

[Run NCBI BLAST on this sequence.]

Detection Method: ORFEUS
Confidence: 14.49
Match: 1m2vB
Description: Sec24
Matching Structure (courtesy of the PDB):

Predicted Domain #3
Region A:
Residues: [508-601]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 AKDVEVIKQL SLDASKTNLR LTDVTNSLSN EEKEKIKMKL KQGQKLFVQV SNFAPQVYII  60
   61 TKNENFLKEV FQLRIFVKEI LEKCAEGIFV VKLD

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below are all of our de novo (Rosetta) predictions for this domain.
Click here to view only most confident match.

    MCM
Score
GO
Score
GO
Term
SCOP
Match
SCOP Description
View Download 0.821 0.001 transcription from RNA polymerase II promoter a.7.1 Spectrin repeat
View Download 0.755 0.001 transcription from RNA polymerase II promoter a.7.8 GAT domain
View Download 0.753 0.001 transcription from RNA polymerase II promoter a.2.6 Effector domain of the protein kinase pkn/prk1
View Download 0.894 0.001 transcription from RNA polymerase II promoter a.7.2 Enzyme IIa from lactose specific PTS, IIa-lac
View Download 0.839 0.001 transcription from RNA polymerase II promoter a.23.1 HSC20 (HSCB), C-terminal oligomerisation domain
View Download 0.722 0.001 transcription from RNA polymerase II promoter a.142.1 PTS-regulatory domain, PRD
View Download 0.684 0.001 transcription from RNA polymerase II promoter a.2.11 Fe,Mn superoxide dismutase (SOD), N-terminal domain
View Download 0.536 0.001 transcription from RNA polymerase II promoter a.47.2 t-snare proteins
View Download 0.527 0.001 transcription from RNA polymerase II promoter a.24.7 FKBP12-rapamycin-binding domain of FKBP-rapamycin-associated protein (FRAP)
View Download 0.523 0.001 transcription from RNA polymerase II promoter a.2.1 GreA transcript cleavage protein, N-terminal domain
View Download 0.511 0.001 transcription from RNA polymerase II promoter a.64.1 Saposin
View Download 0.479 0.001 transcription from RNA polymerase II promoter a.30.2 Homodimeric domain of signal transducing histidine kinase
View Download 0.473 0.001 transcription from RNA polymerase II promoter a.60.9 lambda integrase-like, N-terminal domain
View Download 0.457 0.001 transcription from RNA polymerase II promoter a.24.17 Group V grass pollen allergen
View Download 0.457 0.001 transcription from RNA polymerase II promoter a.46.1 Methionine synthase domain
View Download 0.434 0.001 transcription from RNA polymerase II promoter a.61.1 Retroviral matrix proteins
View Download 0.434 0.001 transcription from RNA polymerase II promoter d.188.1 Prokaryotic ribosomal protein L17
View Download 0.422 0.001 transcription from RNA polymerase II promoter a.7.7 BAG domain
View Download 0.420 0.001 transcription from RNA polymerase II promoter a.78.1 Fatty acid responsive transcription factor FadR, C-terminal domain
View Download 0.416 0.001 transcription from RNA polymerase II promoter d.45.1 ClpS-like
View Download 0.414 0.001 transcription from RNA polymerase II promoter f.36.1 Neurotransmitter-gated ion-channel pransmembrane pore
View Download 0.412 0.001 transcription from RNA polymerase II promoter a.27.1 Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases
View Download 0.394 0.001 transcription from RNA polymerase II promoter a.4.5 "Winged helix" DNA-binding domain
View Download 0.388 0.001 transcription from RNA polymerase II promoter a.22.1 Histone-fold
View Download 0.363 0.001 transcription from RNA polymerase II promoter b.34.9 Tudor/PWWP/MBT
View Download 0.359 0.001 transcription from RNA polymerase II promoter a.36.1 Signal peptide-binding domain
View Download 0.359 0.001 transcription from RNA polymerase II promoter a.130.1 Chorismate mutase II
View Download 0.355 0.001 transcription from RNA polymerase II promoter a.80.1 DNA polymerase III clamp loader subunits, C-terminal domain
View Download 0.354 0.001 transcription from RNA polymerase II promoter d.150.1 4'-phosphopantetheinyl transferase
View Download 0.343 0.001 transcription from RNA polymerase II promoter a.4.5 "Winged helix" DNA-binding domain
View Download 0.339 0.001 transcription from RNA polymerase II promoter d.43.1 Elongation factor Ts (EF-Ts), dimerisation domain
View Download 0.339 0.001 transcription from RNA polymerase II promoter d.68.3 SirA-like
View Download 0.329 0.001 transcription from RNA polymerase II promoter a.60.5 Barrier-to-autointegration factor, BAF
View Download 0.320 0.001 transcription from RNA polymerase II promoter d.58.16 Poly(A) polymerase, C-terminal domain
View Download 0.314 0.001 transcription from RNA polymerase II promoter c.17.1 Caspase-like
View Download 0.311 0.001 transcription from RNA polymerase II promoter a.7.6 Ribosomal protein S20
View Download 0.304 0.001 transcription from RNA polymerase II promoter a.29.4 RecG, N-terminal domain
View Download 0.302 0.001 transcription from RNA polymerase II promoter b.40.2 Bacterial enterotoxins
View Download 0.300 0.001 transcription from RNA polymerase II promoter a.39.1 EF-hand
View Download 0.297 0.001 transcription from RNA polymerase II promoter a.1.1 Globin-like
View Download 0.294 0.001 transcription from RNA polymerase II promoter a.7.7 BAG domain
View Download 0.291 0.001 transcription from RNA polymerase II promoter a.7.1 Spectrin repeat
View Download 0.281 0.001 transcription from RNA polymerase II promoter a.60.6 DNA polymerase beta, N-terminal domain-like
View Download 0.280 0.001 transcription from RNA polymerase II promoter a.24.13 Domain of the SRP/SRP receptor G-proteins
View Download 0.280 0.001 transcription from RNA polymerase II promoter a.71.1 Endoplasmic reticulum protein ERP29, C-domain
View Download 0.278 0.001 transcription from RNA polymerase II promoter d.58.17 Metal-binding domain
View Download 0.276 0.001 transcription from RNA polymerase II promoter a.64.1 Saposin
View Download 0.276 0.001 transcription from RNA polymerase II promoter d.58.20 NAD-binding domain of HMG-CoA reductase
View Download 0.274 0.001 transcription from RNA polymerase II promoter a.8.2 Plasmid maintenance system epsilon/zeta, antidote epsilon subunit
View Download 0.272 0.001 transcription from RNA polymerase II promoter d.41.3 Pyrimidine nucleoside phosphorylase C-terminal domain
View Download 0.271 0.001 transcription from RNA polymerase II promoter c.55.3 Ribonuclease H-like
View Download 0.267 0.001 transcription from RNA polymerase II promoter a.177.1 Sigma2 domain of RNA polymerase sigma factors
View Download 0.258 0.001 transcription from RNA polymerase II promoter d.87.2 CO dehydrogenase flavoprotein C-terminal domain-like
View Download 0.254 0.001 transcription from RNA polymerase II promoter d.58.47 Hypothetical protein VC0424
View Download 0.252 0.001 transcription from RNA polymerase II promoter f.21.2 Fumarate reductase respiratory complex transmembrane subunits
View Download 0.250 0.001 transcription from RNA polymerase II promoter d.52.3 Prokaryotic type KH domain (KH-domain type II)
View Download 0.249 0.001 transcription from RNA polymerase II promoter d.54.1 Enolase N-terminal domain-like
View Download 0.248 0.001 transcription from RNA polymerase II promoter c.47.1 Thioredoxin-like
View Download 0.247 0.001 transcription from RNA polymerase II promoter a.36.1 Signal peptide-binding domain
View Download 0.246 0.001 transcription from RNA polymerase II promoter d.55.1 Ribosomal protein L22
View Download 0.245 0.001 transcription from RNA polymerase II promoter a.133.1 Phospholipase A2, PLA2
View Download 0.240 0.001 transcription from RNA polymerase II promoter c.47.1 Thioredoxin-like
View Download 0.238 0.001 transcription from RNA polymerase II promoter a.4.3 ARID-like
View Download 0.238 0.001 transcription from RNA polymerase II promoter a.24.10 Histidine-containing phosphotransfer domain, HPT domain
View Download 0.230 0.001 transcription from RNA polymerase II promoter a.29.2 Bromodomain
View Download 0.228 0.001 transcription from RNA polymerase II promoter a.26.1 4-helical cytokines
View Download 0.221 0.001 transcription from RNA polymerase II promoter i.11.1 Computational models partly based on NMR data
View Download 0.220 0.001 transcription from RNA polymerase II promoter d.58.20 NAD-binding domain of HMG-CoA reductase
View Download 0.220 0.001 transcription from RNA polymerase II promoter c.55.4 Translational machinery components
View Download 0.213 0.001 transcription from RNA polymerase II promoter a.90.1 Transcription factor STAT-4 N-domain
View Download 0.213 0.001 transcription from RNA polymerase II promoter d.52.1 Alpha-lytic protease prodomain
View Download 0.203 0.001 transcription from RNA polymerase II promoter c.47.1 Thioredoxin-like

Predicted Domain #4
Region A:
Residues: [602-681]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 TVDRLIIKYQ KYWESMRIQI LRRQAILRQQ QQMANNNGNP GTTSTGNNNN IATQQNMQQS  60
   61 LQQMQHLQQL KMQQQQQQQQ 

[Run NCBI BLAST on this sequence.]

Detection Method: MSA

Shown below are all of our structure predictions for this domain.
Click here to view only most confident match.

    MCM
Score
GO
Score
GO
Term
SCOP
Match
SCOP Description
View Download 0.637 0.667 transcription from RNA polymerase II promoter a.35.1 lambda repressor-like DNA-binding domains
View Download 0.691 0.002 transcription from RNA polymerase II promoter a.47.2 t-snare proteins
View Download 0.621 0.002 transcription from RNA polymerase II promoter a.144.1 PABC (PABP) domain
View Download 0.656 0.001 transcription from RNA polymerase II promoter a.2.7 tRNA-binding arm
View Download 0.603 0.000 transcription from RNA polymerase II promoter f.17.1 F1F0 ATP synthase subunit C
View Download 0.595 N/A N/A a.51.1 Cytochrome c oxidase subunit h
View Download 0.586 N/A N/A a.156.1 S13-like H2TH domain
View Download 0.567 N/A N/A a.118.1 ARM repeat
View Download 0.545 N/A N/A a.2.11 Fe,Mn superoxide dismutase (SOD), N-terminal domain
View Download 0.530 N/A N/A a.60.6 DNA polymerase beta, N-terminal domain-like
View Download 0.527 N/A N/A a.8.3 Families 57/38 glycoside transferase middle domain
View Download 0.485 N/A N/A a.35.1 lambda repressor-like DNA-binding domains
View Download 0.470 N/A N/A a.24.16 Nucleotidyltransferase substrate binding subunit/domain
View Download 0.470 N/A N/A c.15.1 BRCT domain
View Download 0.441 N/A N/A a.46.2 Nucleoside phosphorylase/phosphoribosyltransferase N-terminal domain
View Download 0.436 N/A N/A a.23.1 HSC20 (HSCB), C-terminal oligomerisation domain
View Download 0.400 N/A N/A a.30.1 ROP protein
View Download 0.389 N/A N/A d.64.1 eIF1-like
View Download 0.389 N/A N/A a.2.1 GreA transcript cleavage protein, N-terminal domain
View Download 0.381 N/A N/A a.2.7 tRNA-binding arm
View Download 0.366 N/A N/A d.58.25 Killer toxin KP6 alpha-subunit
View Download 0.363 N/A N/A a.45.1 Glutathione S-transferase (GST), C-terminal domain
View Download 0.362 N/A N/A f.36.1 Neurotransmitter-gated ion-channel pransmembrane pore
View Download 0.357 N/A N/A a.52.1 Bifunctional inhibitor/lipid-transfer protein/seed storage 2S albumin
View Download 0.354 N/A N/A a.46.2 Nucleoside phosphorylase/phosphoribosyltransferase N-terminal domain
View Download 0.352 N/A N/A a.2.11 Fe,Mn superoxide dismutase (SOD), N-terminal domain
View Download 0.350 N/A N/A a.44.1 Disulphide-bond formation facilitator (DSBA), insertion domain
View Download 0.343 N/A N/A a.2.2 Ribosomal protein L29 (L29p)
View Download 0.339 N/A N/A d.57.1 DNA damage-inducible protein DinI
View Download 0.312 N/A N/A a.7.6 Ribosomal protein S20
View Download 0.310 N/A N/A a.30.2 Homodimeric domain of signal transducing histidine kinase
View Download 0.299 N/A N/A a.2.7 tRNA-binding arm
View Download 0.289 N/A N/A a.7.7 BAG domain
View Download 0.288 N/A N/A a.30.2 Homodimeric domain of signal transducing histidine kinase
View Download 0.286 N/A N/A d.43.1 Elongation factor Ts (EF-Ts), dimerisation domain
View Download 0.284 N/A N/A a.2.5 Prefoldin
View Download 0.278 N/A N/A d.58.7 RNA-binding domain, RBD
View Download 0.274 N/A N/A a.24.4 Hemerythrin
View Download 0.267 N/A N/A a.44.1 Disulphide-bond formation facilitator (DSBA), insertion domain
View Download 0.265 N/A N/A a.60.9 lambda integrase-like, N-terminal domain
View Download 0.258 N/A N/A a.163.1 Crustacean CHH/MIH/GIH neurohormone
View Download 0.258 N/A N/A d.129.1 TATA-box binding protein-like
View Download 0.248 N/A N/A a.8.3 Families 57/38 glycoside transferase middle domain
View Download 0.232 N/A N/A a.7.7 BAG domain
View Download 0.228 N/A N/A d.88.1 SRF-like
View Download 0.223 N/A N/A d.201.1 SRP19
View Download 0.221 N/A N/A a.2.3 Chaperone J-domain
View Download 0.218 N/A N/A a.133.1 Phospholipase A2, PLA2
View Download 0.218 N/A N/A d.39.1 Dynein light chain 8 (DLC8)
View Download 0.217 N/A N/A a.16.1 S15/NS1 RNA-binding domain
View Download 0.214 N/A N/A c.47.1 Thioredoxin-like
View Download 0.209 N/A N/A d.34.1 DNA-binding domain of Mlu1-box binding protein MBP1
View Download 0.209 N/A N/A a.7.2 Enzyme IIa from lactose specific PTS, IIa-lac
View Download 0.207 N/A N/A a.18.1 T4 endonuclease V
View Download 0.207 N/A N/A d.58.10 Acylphosphatase-like
View Download 0.205 N/A N/A a.59.1 PAH2 domain
View Download 0.205 N/A N/A f.28.1 Nonheme 11 kDa protein of cytochrome bc1 complex (Ubiquinol-cytochrome c reductase)
View Download 0.202 N/A N/A d.58.17 Metal-binding domain
View Download 0.202 N/A N/A a.64.1 Saposin

Predicted Domain #5
Region A:
Residues: [682-916]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 QQQQQQQQQQ QQQQQHIYPS STPGVANYSA MANAPGNNIP YMNHKNTSSM DFLNSMENTP  60
   61 KVPVSAAATP SLNKTINGKV NGRTKSNTIP VTSIPSTNKK LSISNAASQQ PTPRSASNTA 120
  121 KSTPNTNPSP LKTQTKNGTP NPNNMKTVQS PMGAQPSYNS AIIENAFRKE ELLLKDLEIR 180
  181 KLEISSRFKH RQEIFKDSPM DLFMSTLGDC LGIKDEEMLT SCTIPKAVVD HINGS

[Run NCBI BLAST on this sequence.]

Detection Method: ORFEUS
Confidence: 14.71
Match: 1k83A
Description: RBP1
Matching Structure (courtesy of the PDB):

Predicted Domain #6
Region A:
Residues: [917-1081]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 GKRKPTKAAQ RARDQDSIDI SIKDNKLVMK SKFNKSNRSY SIALSNVAAI FKGIGGNFKD  60
   61 LSTLVHSSSP STSSNMDVGN PRKRKASVLE ISPQDSIASV LSPDSNIMSD SKKIKVDSPD 120
  121 DPFMTKSGAT TSEKQEVTNE APFLTSGTSS EQFNVWDWNN WTSAT

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below are all of our de novo (Rosetta) predictions for this domain.
Click here to view only most confident match.

Found no structure predictions for this domain.


YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle