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View Structure Prediction Details

Protein: HRD1
Organism: Saccharomyces cerevisiae
Length: 551 amino acids
Reference: Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for HRD1.

Description E-value Query
Range
Subject
Range
gi|76657864 - gi|76657864|ref|XP_886351.1| PREDICTED: similar to synoviolin 1 isoform a isoform 5 [Bos taurus]
325.0 [0..9] [404..3]
gi|26334416, gi|... - gi|29145030|gb|AAH46829.1| Syvn1 protein [Mus musculus], gi|26334416|dbj|BAB23474.2| unnamed protein...
321.0 [0..9] [404..3]
gi|28460644 - gi|28460644|dbj|BAC57449.1| Synoviolin1 [Homo sapiens]
321.0 [0..9] [404..3]
gi|109105529 - gi|109105529|ref|XP_001114254.1| PREDICTED: similar to synoviolin 1 isoform a [Macaca mulatta]
319.0 [0..9] [404..3]
gi|62641776, gi|... - gi|62641776|ref|XP_342000.2| PREDICTED: similar to synoviolin 1 isoform a isoform 2 [Rattus norvegic...
319.0 [0..9] [404..3]

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Predicted Domain #1
Region A:
Residues: [1-221]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MVPENRRKQL AIFVVVTYLL TFYCVYSATK TSVSFLQVTL KLNEGFNLMV LSIFILLNST  60
   61 LLWQLLTKLL FGELRLIEHE HIFERLPFTI INTLFMSSLF HERYFFTVAF FGLLLLYLKV 120
  121 FHWILKDRLE ALLQSINDST TMKTLIFSRF SFNLVLLAVV DYQIITRCIS SIYTNQKSDI 180
  181 ESTSLYLIQV MEFTMLLIDL LNLFLQTCLN FWEFYRSQQS L

[Run NCBI BLAST on this sequence.]

Detection Method: MSA

Shown below are all of our structure predictions for this domain.
Click here to view only most confident match.

Found no structure predictions for this domain.

Predicted Domain #2
Region A:
Residues: [222-344]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 SNENNHIVHG DPTDENTVES DQSQPVLNDD DDDDDDDRQF TGLEGKFMYE KAIDVFTRFL  60
   61 KTALHLSMLI PFRMPMMLLK DVVWDILALY QSGTSLWKIW RNNKQLDDTL VTVTVEQLQN 120
  121 SAN

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below are all of our de novo (Rosetta) predictions for this domain.
Click here to view only most confident match.

    MCM
Score
SCOP
Match
SCOP Description
View Download 0.587 a.7.7 BAG domain
View Download 0.531 a.219.1 Description not found.
View Download 0.528 a.177.1 Sigma2 domain of RNA polymerase sigma factors
View Download 0.528 a.112.1 Description not found.
View Download 0.423 d.227.1 OsmC-like
View Download 0.389 a.24.9 alpha-catenin/vinculin
View Download 0.367 a.62.1 Hepatitis B viral capsid (hbcag)
View Download 0.365 a.45.1 Glutathione S-transferase (GST), C-terminal domain
View Download 0.337 f.32.1 a domain/subunit of cytochrome bc1 complex (Ubiquinol-cytochrome c reductase)

Predicted Domain #3
Region A:
Residues: [345-432]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 DDNICIICMD ELIHSPNQQT WKNKNKKPKR LPCGHILHLS CLKNWMERSQ TCPICRLPVF  60
   61 DEKGNVVQTT FTSNSDITTQ TTVTDSTG

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 31.232149
Match: 1chcA
Description: STRUCTURE OF THE C3HC4 DOMAIN BY 1H-NUCLEAR MAGNETIC RESONANCE SPECTROSCOPY; A NEW STRUCTURAL CLASS OF ZINC-FINGER
Matching Structure (courtesy of the PDB):

Predicted Domain #4
Region A:
Residues: [433-551]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 IATDQQGFAN EVDLLPTRTT SPDIRIVPTQ NIDTLAMRTR STSTPSPTWY TFPLHKTGDN  60
   61 SVGSSRSAYE FLITNSDEKE NGIPVKLTIE NHEVNSLHGD GGEQIAKKIV IPDKFIQHI

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below are all of our de novo (Rosetta) predictions for this domain.
Click here to view only most confident match.

    MCM
Score
SCOP
Match
SCOP Description
View Download 0.470 c.52.1 Restriction endonuclease-like
View Download 0.422 c.52.1 Restriction endonuclease-like
View Download 0.334 b.84.2 Rudiment single hybrid motif
View Download 0.319 c.51.1 Anticodon-binding domain of Class II aaRS
View Download 0.319 c.51.1 Anticodon-binding domain of Class II aaRS
View Download 0.285 d.108.1 Acyl-CoA N-acyltransferases (Nat)
View Download 0.255 d.24.1 Pili subunits
View Download 0.225 d.93.1 SH2 domain


YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle