






| Protein: | FRE4 |
| Organism: | Saccharomyces cerevisiae |
| Length: | 719 amino acids |
| Reference: | Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076 |
Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for FRE4.
| Description | E-value | Query Range |
Subject Range |
|
|
0.0 | [1..719] | [1..711] |
|
|
0.0 | [69..717] | [237..948] |
|
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0.0 | [69..717] | [244..962] |
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0.0 | [69..717] | [233..944] |
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0.0 | [69..717] | [214..938] |
|
Region A: Residues: [1-212] |
1 11 21 31 41 51
| | | | | |
1 MLLVHIISFL LFFQLSAAKA PPSKTSLINT HERRSIYSCY VGLRKETWGF NGSAICRYEP 60
61 AIQSMLYCLY EDTHEKGYSN KTLEKGFEEM RQFCYTPKFL NMTDAEFYTS LDNGTYYIQD 120
121 QPKAGINITY PIRLNTTLRK AYYDAYYGYY YNHDIPYYFG GIICAYFVGV MLLAGLIRFL 180
181 NYTPIKKIMF QQKLVNYVRG YTTLPTLYEK HA
|
Shown below is our most confident prediction for this domain.
Click here to view all matches.
Found no confident structure predictions for this domain.
|
Region A: Residues: [213-336] |
1 11 21 31 41 51
| | | | | |
1 EPFSYLKVIT GYLPTRFETL VILGYLILHT IFMAYKYQYD PYHIIFAAHR AEVAHFVAYR 60
61 SGILSFAHLP LIVLFAGRNN FLQLISGLKH TSFIVFHKWL GRMMFLDAII HAAGFTNYYL 120
121 YYKK
|
Shown below is our most confident prediction for this domain.
Click here to view all matches.
| MCM Score |
GO Score |
GO Term |
SCOP Match |
SCOP Description | ||
| View | Download | 0.934 | N/A | N/A | a.7.1 | Spectrin repeat |
|
Region A: Residues: [337-396] |
1 11 21 31 41 51
| | | | | |
1 WNTVRLRVYW KFGIATTCLA GMLIFFSIAA FRRHYYETFM ALHIVFAALF LYTCWEHVTN 60
61
|
Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.
Found no confident structure predictions for this domain.
| Term | Confidence | Notes |
| catalytic activity | 1.45374095556065 | bayes_pls_golite062009 |
| transferase activity | 1.15480450573972 | bayes_pls_golite062009 |
| binding | 1.13408475648113 | bayes_pls_golite062009 |
| oxidoreductase activity | 0.27336340260908 | bayes_pls_golite062009 |
| protein binding | 0.144900113694048 | bayes_pls_golite062009 |
| cofactor binding | 0.0731141170494622 | bayes_pls_golite062009 |
|
Region A: Residues: [397-521] |
1 11 21 31 41 51
| | | | | |
1 FSGIEWIYAA IAIWGVDRIV RITRIALLGF PKADLQLVGS DLVRVTVKKP KKFWKAKPGQ 60
61 YVFVSFLRPL CFWQSHPFTV MDSCVNDREL VIVLKAKKGV TKLVRNFVER KGGKASMRLA 120
121 IEGPY
|
| Detection Method: | |
| Confidence: | 51.39794 |
| Match: | 1cnf__ |
| Description: | Nitrate reductase core domain; Nitrate reductase |
Matching Structure (courtesy of the PDB):![]() |
|
|
Region A: Residues: [522-646] |
1 11 21 31 41 51
| | | | | |
1 GSKSTAHRFD NVLLLAGGSG LPGPISHALE LGKTTAASGK NFVQLVIAVR GLDMLNACKK 60
61 ELMALKGLNV QVHIYNSKQE LASAEKISSN EVKNGETTAE KAPSSLSNSE KAPSESENTE 120
121 LPLSL
|
| Detection Method: | |
| Confidence: | 51.39794 |
| Match: | 1cnf__ |
| Description: | Nitrate reductase core domain; Nitrate reductase |
Matching Structure (courtesy of the PDB):![]() |
|
|
Region A: Residues: [647-719] |
1 11 21 31 41 51
| | | | | |
1 NDTSISDLEF ATFHVGRPNV EEILNESVNH SGSLAVVCCG PPIFVDTARN QTAKAVIRNP 60
61 SRMIEYLEEY QAW
|
Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.
| MCM Score |
GO Score |
GO Term |
SCOP Match |
SCOP Description | ||
| View | Download | 0.833 | 0.000 | plasma membrane | d.68.3 | SirA-like |