| Protein: | FRE4 |
| Organism: | Saccharomyces cerevisiae |
| Length: | 719 amino acids |
| Reference: | Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076 |
Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for FRE4.
| Description | E-value | Query Range |
Subject Range |
|
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0.0 | [1..719] | [1..711] |
|
|
0.0 | [69..717] | [237..948] |
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0.0 | [69..717] | [244..962] |
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0.0 | [69..717] | [233..944] |
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0.0 | [69..717] | [214..938] |
|
Region A: Residues: [1-212] |
1 11 21 31 41 51
| | | | | |
1 MLLVHIISFL LFFQLSAAKA PPSKTSLINT HERRSIYSCY VGLRKETWGF NGSAICRYEP 60
61 AIQSMLYCLY EDTHEKGYSN KTLEKGFEEM RQFCYTPKFL NMTDAEFYTS LDNGTYYIQD 120
121 QPKAGINITY PIRLNTTLRK AYYDAYYGYY YNHDIPYYFG GIICAYFVGV MLLAGLIRFL 180
181 NYTPIKKIMF QQKLVNYVRG YTTLPTLYEK HA
|
| Detection Method: |  |
Shown below are all of our structure predictions for this domain.
Click here to view only most confident match.
Found no structure predictions for this domain.
|
Region A: Residues: [213-336] |
1 11 21 31 41 51
| | | | | |
1 EPFSYLKVIT GYLPTRFETL VILGYLILHT IFMAYKYQYD PYHIIFAAHR AEVAHFVAYR 60
61 SGILSFAHLP LIVLFAGRNN FLQLISGLKH TSFIVFHKWL GRMMFLDAII HAAGFTNYYL 120
121 YYKK
|
| Detection Method: | |
Shown below are all of our structure predictions for this domain.
Click here to view only most confident match.
| MCM Score |
GO Score |
GO Term |
SCOP Match |
SCOP Description | ||
| View | Download | 0.934 | N/A | N/A | a.7.1 | Spectrin repeat |
| View | Download | 0.856 | N/A | N/A | a.24.1 | Apolipoprotein |
| View | Download | 0.794 | N/A | N/A | a.7.1 | Spectrin repeat |
| View | Download | 0.777 | N/A | N/A | a.7.1 | Spectrin repeat |
| View | Download | 0.747 | N/A | N/A | a.24.1 | Apolipoprotein |
|
Region A: Residues: [337-396] |
1 11 21 31 41 51
| | | | | |
1 WNTVRLRVYW KFGIATTCLA GMLIFFSIAA FRRHYYETFM ALHIVFAALF LYTCWEHVTN 60
61
|
| Detection Method: | |
Shown below are all of our de novo (Rosetta) predictions for this domain.
Click here to view only most confident match.
Found no structure predictions for this domain.
| Term | Confidence | Notes |
| catalytic activity | 1.45374095556065 | bayes_pls_golite062009 |
| transferase activity | 1.15480450573972 | bayes_pls_golite062009 |
| binding | 1.13408475648113 | bayes_pls_golite062009 |
| oxidoreductase activity | 0.27336340260908 | bayes_pls_golite062009 |
| protein binding | 0.144900113694048 | bayes_pls_golite062009 |
| cofactor binding | 0.0731141170494622 | bayes_pls_golite062009 |
|
Region A: Residues: [397-521] |
1 11 21 31 41 51
| | | | | |
1 FSGIEWIYAA IAIWGVDRIV RITRIALLGF PKADLQLVGS DLVRVTVKKP KKFWKAKPGQ 60
61 YVFVSFLRPL CFWQSHPFTV MDSCVNDREL VIVLKAKKGV TKLVRNFVER KGGKASMRLA 120
121 IEGPY
|
| Detection Method: | |
| Confidence: | 51.39794 |
| Match: | 1cnf__ |
| Description: | Nitrate reductase core domain; Nitrate reductase |
Matching Structure (courtesy of the PDB): |
|
|
Region A: Residues: [522-646] |
1 11 21 31 41 51
| | | | | |
1 GSKSTAHRFD NVLLLAGGSG LPGPISHALE LGKTTAASGK NFVQLVIAVR GLDMLNACKK 60
61 ELMALKGLNV QVHIYNSKQE LASAEKISSN EVKNGETTAE KAPSSLSNSE KAPSESENTE 120
121 LPLSL
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| Detection Method: | |
| Confidence: | 51.39794 |
| Match: | 1cnf__ |
| Description: | Nitrate reductase core domain; Nitrate reductase |
| Matching Structure (courtesy of the PDB): |
|
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Region A: Residues: [647-719] |
1 11 21 31 41 51
| | | | | |
1 NDTSISDLEF ATFHVGRPNV EEILNESVNH SGSLAVVCCG PPIFVDTARN QTAKAVIRNP 60
61 SRMIEYLEEY QAW
|
| Detection Method: | |
Shown below are all of our de novo (Rosetta) predictions for this domain.
Click here to view only most confident match.
| MCM Score |
GO Score |
GO Term |
SCOP Match |
SCOP Description | ||
| View | Download | 0.833 | 0.000 | plasma membrane | d.68.3 | SirA-like |
| View | Download | 0.737 | 0.000 | plasma membrane | d.68.1 | Translation initiation factor IF3, C-terminal domain |
| View | Download | 0.652 | 0.000 | plasma membrane | d.68.4 | YhbY-like |
| View | Download | 0.784 | 0.000 | plasma membrane | d.68.3 | SirA-like |
| View | Download | 0.635 | 0.000 | plasma membrane | c.25.1 | Ferredoxin reductase-like, C-terminal NADP-linked domain |
| View | Download | 0.613 | 0.000 | plasma membrane | c.13.2 | Anti-sigma factor antagonist SpoIIaa |
| View | Download | 0.595 | 0.000 | plasma membrane | c.58.1 | Aminoacid dehydrogenase-like, N-terminal domain |
| View | Download | 0.582 | 0.000 | plasma membrane | d.45.1 | ClpS-like |
| View | Download | 0.559 | 0.000 | plasma membrane | c.102.1 | Cell-division inhibitor MinC, N-terminal domain |
| View | Download | 0.548 | 0.000 | plasma membrane | c.23.6 | Cobalamin (vitamin B12)-binding domain |
| View | Download | 0.450 | 0.000 | plasma membrane | c.47.1 | Thioredoxin-like |
| View | Download | 0.444 | 0.000 | plasma membrane | c.2.1 | NAD(P)-binding Rossmann-fold domains |
| View | Download | 0.436 | 0.000 | plasma membrane | d.68.6 | DNA-binding protein Sso10b (AlbA) |
| View | Download | 0.435 | 0.000 | plasma membrane | d.50.1 | dsRNA-binding domain-like |
| View | Download | 0.385 | 0.000 | plasma membrane | d.109.1 | Actin depolymerizing proteins |
| View | Download | 0.366 | 0.000 | plasma membrane | d.58.12 | eEF-1beta-like |
| View | Download | 0.365 | 0.000 | plasma membrane | d.58.7 | RNA-binding domain, RBD |
| View | Download | 0.363 | 0.000 | plasma membrane | c.23.5 | Flavoproteins |
| View | Download | 0.354 | 0.000 | plasma membrane | d.50.2 | Porphobilinogen deaminase (hydroxymethylbilane synthase), C-terminal domain |
| View | Download | 0.344 | 0.000 | plasma membrane | c.95.1 | Thiolase-like |
| View | Download | 0.339 | 0.000 | plasma membrane | c.2.1 | NAD(P)-binding Rossmann-fold domains |
| View | Download | 0.333 | 0.000 | plasma membrane | d.79.2 | Tubulin/Dihydroxyacetone kinase C-terminal domain |
| View | Download | 0.331 | 0.000 | plasma membrane | a.4.5 | "Winged helix" DNA-binding domain |
| View | Download | 0.324 | 0.000 | plasma membrane | c.46.1 | Rhodanese/Cell cycle control phosphatase |
| View | Download | 0.320 | 0.000 | plasma membrane | c.37.1 | P-loop containing nucleoside triphosphate hydrolases |
| View | Download | 0.310 | 0.000 | plasma membrane | c.23.4 | Succinyl-CoA synthetase domains |
| View | Download | 0.309 | 0.000 | plasma membrane | c.5.1 | MurCD N-terminal domain |
| View | Download | 0.305 | 0.000 | plasma membrane | d.79.1 | YjgF-like |
| View | Download | 0.305 | 0.000 | plasma membrane | d.58.5 | GlnB-like |
| View | Download | 0.297 | 0.000 | plasma membrane | c.23.1 | CheY-like |
| View | Download | 0.289 | 0.000 | plasma membrane | d.58.4 | Dimeric alpha+beta barrel |
| View | Download | 0.286 | 0.000 | plasma membrane | g.3.7 | Scorpion toxin-like |
| View | Download | 0.286 | 0.000 | plasma membrane | d.68.5 | C-terminal domain of ProRS |
| View | Download | 0.285 | 0.000 | plasma membrane | b.36.1 | PDZ domain-like |
| View | Download | 0.278 | 0.000 | plasma membrane | c.9.1 | Barstar (barnase inhibitor) |
| View | Download | 0.274 | 0.000 | plasma membrane | d.15.7 | Immunoglobulin-binding domains |
| View | Download | 0.272 | 0.000 | plasma membrane | c.16.1 | Lumazine synthase |
| View | Download | 0.272 | 0.000 | plasma membrane | c.2.1 | NAD(P)-binding Rossmann-fold domains |
| View | Download | 0.270 | 0.000 | plasma membrane | g.7.1 | Snake toxin-like |
| View | Download | 0.268 | 0.000 | plasma membrane | d.58.7 | RNA-binding domain, RBD |
| View | Download | 0.267 | 0.000 | plasma membrane | d.58.7 | RNA-binding domain, RBD |
| View | Download | 0.264 | 0.000 | plasma membrane | c.37.1 | P-loop containing nucleoside triphosphate hydrolases |
| View | Download | 0.263 | 0.000 | plasma membrane | c.2.1 | NAD(P)-binding Rossmann-fold domains |
| View | Download | 0.260 | 0.000 | plasma membrane | c.2.1 | NAD(P)-binding Rossmann-fold domains |
| View | Download | 0.259 | 0.000 | plasma membrane | c.78.2 | Aspartate/glutamate racemase |
| View | Download | 0.255 | 0.000 | plasma membrane | d.68.7 | R3H domain |
| View | Download | 0.250 | 0.000 | plasma membrane | d.226.1 | GIY-YIG endonuclease |
| View | Download | 0.239 | 0.000 | plasma membrane | d.58.7 | RNA-binding domain, RBD |
| View | Download | 0.239 | 0.000 | plasma membrane | c.25.1 | Ferredoxin reductase-like, C-terminal NADP-linked domain |
| View | Download | 0.234 | 0.000 | plasma membrane | d.58.49 | YajQ-like |
| View | Download | 0.233 | 0.000 | plasma membrane | c.58.1 | Aminoacid dehydrogenase-like, N-terminal domain |
| View | Download | 0.232 | 0.000 | plasma membrane | d.11.1 | Penicillin-binding protein 2x (pbp-2x), c-terminal domain |
| View | Download | 0.230 | 0.000 | plasma membrane | g.3.7 | Scorpion toxin-like |
| View | Download | 0.228 | 0.000 | plasma membrane | d.12.1 | Ribosomal proteins L23 and L15e |
| View | Download | 0.225 | 0.000 | plasma membrane | d.11.1 | Penicillin-binding protein 2x (pbp-2x), c-terminal domain |
| View | Download | 0.224 | 0.000 | plasma membrane | c.97.1 | Cytidine deaminase-like |
| View | Download | 0.221 | 0.000 | plasma membrane | d.58.12 | eEF-1beta-like |
| View | Download | 0.219 | 0.000 | plasma membrane | c.37.1 | P-loop containing nucleoside triphosphate hydrolases |
| View | Download | 0.213 | 0.000 | plasma membrane | c.84.1 | Phosphoglucomutase, first 3 domains |
| View | Download | 0.208 | 0.000 | plasma membrane | c.58.1 | Aminoacid dehydrogenase-like, N-terminal domain |
| View | Download | 0.205 | 0.000 | plasma membrane | g.10.1 | Hairpin loop containing domain-like |
| View | Download | 0.204 | 0.000 | plasma membrane | c.48.1 | TK C-terminal domain-like |
| View | Download | 0.204 | 0.000 | plasma membrane | c.59.1 | MurD-like peptide ligases, peptide-binding domain |
