YRC Public Data Repository - Protein Structure Prediction

Protein:	BIO4
Organism:	Saccharomyces cerevisiae
Length:	237 amino acids
Reference:	Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for BIO4.

Description	E-value	Query Range	Subject Range
gi\|2127822 - gi\|2127822\|pir\|\|D64360 cobyric acid synthase homolog - Methanococcus jannaschii gi\|15668661, gi\|... - gi\|1591187\|gb\|AAB98475.1\| cobyric acid synthase (cbiP) [Methanocaldococcus jannaschii DSM 2661], gi\|...	4.0E-48	[9..229]	[2..248]
COBQ_METJA - Probable cobyric acid synthase OS=Methanocaldococcus jannaschii (strain ATCC 43067 / DSM 2661 / JAL-... COBQ_METJA - Probable cobyric acid synthase OS=Methanocaldococcus jannaschii GN=cobQ PE=3 SV=2	1.0E-47	[14..229]	[5..245]
gi\|7450301 - gi\|7450301\|pir\|\|B69205 cobyric acid synthase - Methanobacterium thermoautotrophicum (strain Delta H) gi\|2621878, gi\|1... - gi\|2621878\|gb\|AAB85289.1\| cobyric acid synthase [Methanothermobacter thermautotrophicus str. Delta H...	1.0E-46	[1..218]	[3..246]
BIOD_YEAST - Dethiobiotin synthetase OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=BIO4 PE=3 SV=1 BIO4 - Dethiobiotin synthetase, catalyzes the third step in the biotin biosynthesis pathway; BIO4 is in a c...	7.0E-46	[1..237]	[1..237]
COBQ_NOSS1 - Cobyric acid synthase OS=Nostoc sp. (strain PCC 7120 / UTEX 2576) GN=cobQ PE=3 SV=1 gi\|25327096 - pir\|\|AB2103 cobyric acid synthase [imported] - Nostoc sp. (strain PCC 7120)	8.0E-46	[9..224]	[1..242]
gi\|7450298 - gi\|7450298\|pir\|\|S76673 hypothetical protein - Synechocystis sp. (strain PCC 6803) gi\|1001778, gi\|1... - gi\|16331819\|ref\|NP_442547.1\| cobyric acid synthase [Synechocystis sp. PCC 6803], gi\|1001778\|dbj\|BAA1...	1.0E-45	[5..214]	[24..259]
COBQ_VIBCH - Cobyric acid synthase OS=Vibrio cholerae serotype O1 (strain ATCC 39315 / El Tor Inaba N16961) GN=co... gi\|121550224, gi... - gi\|121585607\|ref\|ZP_01675403.1\| cobyric acid synthase CobQ [Vibrio cholerae 2740-80], gi\|121550224\|g... COBQ_VIBCH - Cobyric acid synthase OS=Vibrio cholerae GN=cobQ PE=3 SV=1 gi\|125619563 - gi\|125619563\|gb\|EAZ48091.1\| cobyric acid synthase [Vibrio cholerae MO10] gi\|153219929, gi... - gi\|153219929\|ref\|ZP_01951498.1\| cobyric acid synthase CobQ [Vibrio cholerae MAK 757], gi\|124120489\|g... gi\|153820733, gi... - gi\|153820733\|ref\|ZP_01973400.1\| cobyric acid synthase [Vibrio cholerae B33], gi\|126521776\|gb\|EAZ7899...	5.0E-45	[12..236]	[3..244]
COBQ_CLOP1 - Cobyric acid synthase OS=Clostridium perfringens (strain ATCC 13124 / DSM 756 / JCM 1290 / NCIMB 612... COBQ_CLOPE - Cobyric acid synthase OS=Clostridium perfringens (strain 13 / Type A) GN=cobQ PE=3 SV=1 COBQ_CLOPE - Cobyric acid synthase OS=Clostridium perfringens GN=cobQ PE=3 SV=1	9.0E-45	[9..218]	[1..236]
gi\|6685341 - gi\|6685341\|sp\|O26880\|COBQ_METTH Probable cobyric acid synthase COBQ_METTH - Probable cobyric acid synthase OS=Methanothermobacter thermautotrophicus (strain ATCC 29096 / DSM 10...	1.0E-44	[9..218]	[1..236]
CBIP_SALTY - Cobyric acid synthase OS=Salmonella typhimurium GN=cbiP PE=3 SV=1 lcl\|NC_016856.1_... - [gene=cbiP] [protein=cobyric acid synthase] [protein_id=YP_005238048.1] [location=complement(2151233... CBIP_SALTY - Cobyric acid synthase OS=Salmonella typhimurium GN=cbiP PE=3 SV=1 CBIP_SALTY - Cobyric acid synthase OS=Salmonella typhimurium (strain LT2 / SGSC1412 / ATCC 700720) GN=cbiP PE=3 S... gi\|167990927, gi... - gi\|205330469\|gb\|EDZ17233.1\| cobyric acid synthase CobQ [Salmonella enterica subsp. enterica serovar ... gi\|168259686, gi... - gi\|205350537\|gb\|EDZ37168.1\| cobyric acid synthase CobQ [Salmonella enterica subsp. enterica serovar ... gi\|197263442, gi... - gi\|197263442\|ref\|ZP_03163516.1\| cobyric acid synthase CobQ [Salmonella enterica subsp. enterica sero...	3.0E-44	[13..218]	[4..235]

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Predicted Domain #1

Region A:
Residues: [1-237]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MNSKSQQQEQ QPIVFVTGTD TDVGKTFVST LLVHKWKAAY WKPVQTGIES DQGDSETLKN  60
   61 FKIAASTWQP PIFTPTYALQ KPLSPLQAME YEPNVDIRLL DFVVPEEWSA ENPLVVEGAG 120
  121 GVCVPITRKL EITTDLIKHL IETSGHPVYV VVVARSGLGT LNHTLLTWNH LCDNGLRSHL 180
  181 FGVILNGEPN EGNVQALKKF GVNIMAQVAQ CTTAHDQDME LHELPSVESL MTQQDVE

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	1396.69897
Match:	1m3tA_
Description:	No description for 1m3tA_ was found.

Predicted functions:

Term	Confidence	Notes
catalytic activity	1.00104173493322	bayes_pls_golite062009

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits

Predicted functions: