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View Structure Prediction Details

Protein: BIO5
Organism: Saccharomyces cerevisiae
Length: 561 amino acids
Reference: Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for BIO5.

Description E-value Query
Range
Subject
Range
YI26_SCHPO - Uncharacterized amino-acid permease P7G5.06 OS=Schizosaccharomyces pombe (strain 972 / ATCC 24843) G...
SPAP7G5.06 - amino acid permease, unknown 4
6.0E-72 [14..558] [57..538]
GNP1_YEAST - High-affinity glutamine permease OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=GNP1 PE...
GNP1 - High-affinity glutamine permease, also transports Leu, Ser, Thr, Cys, Met and Asn; expression is ful...
4.0E-67 [25..555] [129..608]
gi|68470470, gi|... - gi|68470731|ref|XP_720611.1| N-acetylglucosamine-inducible general amino acid permease [Candida albi...
gi|18568390 - gi|18568390|gb|AAL76065.1| Gap1 protein [Candida albicans]
gi|238882678 - gi|238882678|gb|EEQ46316.1| general amino-acid permease GAP1 [Candida albicans WO-1]
6.0E-67 [18..555] [48..527]
gi|7507776 - gi|7507776|pir||T16867 probable cytochrome P450 T13C5.1 [similarity] - Caenorhabditis elegans
7.0E-66 [14..558] [50..534]
INDA1_HYPAT - Amino-acid permease inda1 OS=Hypocrea atroviridis GN=inda1 PE=2 SV=1
INDA1_TRIHA, INA... - (P34054) Amino-acid permease inda1, (P34054) Amino-acid permease inda1
3.0E-64 [39..556] [59..525]

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Predicted Domain #1
Region A:
Residues: [1-154]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MNRVGAVFLF VYERNFFLSI VPDRHRTEIR MSSSERSEVK FDKHFNWWSL LGIAFSLSCS  60
   61 WVGISASMAV GIASGGPLLI IYGLIIAAFF SLMCGISLGD FAAILPNSSG GSFWVLKMLE 120
  121 QESVTLKTPE YEDPSDDDEE VFLENYCQTF NVEV

[Run NCBI BLAST on this sequence.]

Detection Method: MSA

Shown below are all of our structure predictions for this domain.
Click here to view only most confident match.

Found no structure predictions for this domain.

Predicted Domain #2
Region A:
Residues: [155-279]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 SSKFQKVSSM VVGLLNYFGA IFTTASICSS LSMSCIGIHK LLHPDYELKH WHVFVGYECI  60
   61 NAVLTLFNIY STPLPYISQF GLYTSLLSFA MTFIICIVSR SDNTVDPWPK ASNIFGSFDN 120
  121 QTGWN

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below are all of our de novo (Rosetta) predictions for this domain.
Click here to view only most confident match.

    MCM
Score
SCOP
Match
SCOP Description
View Download 0.710 a.1.1 Globin-like
View Download 0.732 a.27.1 Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases
View Download 0.668 a.7.3 Succinate dehydrogenase/fumarate reductase flavoprotein C-terminal domain
View Download 0.653 a.4.9 Polynucleotide phosphorylase/guanosine pentaphosphate synthase (PNPase/GPSI), domain 3
View Download 0.689 a.182.1 GatB/YqeY domain
View Download 0.618 f.36.1 Neurotransmitter-gated ion-channel pransmembrane pore
View Download 0.616 a.46.1 Methionine synthase domain
View Download 0.603 a.24.10 Histidine-containing phosphotransfer domain, HPT domain
View Download 0.572 a.133.1 Phospholipase A2, PLA2
View Download 0.564 a.74.1 Cyclin-like
View Download 0.548 f.36.1 Neurotransmitter-gated ion-channel pransmembrane pore
View Download 0.547 d.81.1 Glyceraldehyde-3-phosphate dehydrogenase-like, C-terminal domain
View Download 0.542 a.8.3 Families 57/38 glycoside transferase middle domain
View Download 0.524 a.29.2 Bromodomain
View Download 0.523 a.4.9 Polynucleotide phosphorylase/guanosine pentaphosphate synthase (PNPase/GPSI), domain 3
View Download 0.518 a.45.1 Glutathione S-transferase (GST), C-terminal domain
View Download 0.504 a.121.1 Tetracyclin repressor-like, C-terminal domain
View Download 0.488 a.80.1 DNA polymerase III clamp loader subunits, C-terminal domain
View Download 0.486 a.100.1 6-phosphogluconate dehydrogenase C-terminal domain-like
View Download 0.480 a.1.1 Globin-like
View Download 0.474 a.74.1 Cyclin-like
View Download 0.473 a.66.1 Transducin (alpha subunit), insertion domain
View Download 0.467 d.6.1 Prion-like
View Download 0.462 a.69.1 C-terminal domain of alpha and beta subunits of F1 ATP synthase
View Download 0.457 a.24.9 alpha-catenin/vinculin
View Download 0.456 a.26.1 4-helical cytokines
View Download 0.451 a.177.1 Sigma2 domain of RNA polymerase sigma factors
View Download 0.450 a.118.8 TPR-like
View Download 0.442 a.27.1 Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases
View Download 0.440 a.63.1 Apolipophorin-III
View Download 0.439 a.70.1 N-terminal domain of the delta subunit of the F1F0-ATP synthase
View Download 0.436 a.24.3 Cytochromes
View Download 0.435 a.26.1 4-helical cytokines
View Download 0.433 a.27.1 Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases
View Download 0.430 a.121.1 Tetracyclin repressor-like, C-terminal domain
View Download 0.427 a.24.16 Nucleotidyltransferase substrate binding subunit/domain
View Download 0.418 a.24.16 Nucleotidyltransferase substrate binding subunit/domain
View Download 0.417 a.19.1 Fertilization protein
View Download 0.417 a.118.1 ARM repeat
View Download 0.411 a.24.7 FKBP12-rapamycin-binding domain of FKBP-rapamycin-associated protein (FRAP)
View Download 0.411 a.24.12 Outer surface protein C (OspC)
View Download 0.385 a.1.1 Globin-like
View Download 0.383 a.29.4 RecG, N-terminal domain
View Download 0.380 a.47.2 t-snare proteins
View Download 0.377 a.7.8 GAT domain
View Download 0.377 a.27.1 Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases
View Download 0.369 a.24.9 alpha-catenin/vinculin
View Download 0.364 d.58.29 Adenylyl and guanylyl cyclase catalytic domain
View Download 0.363 f.34.1 Mechanosensitive channel protein MscS (YggB), transmembrane region
View Download 0.362 a.7.1 Spectrin repeat
View Download 0.362 a.52.1 Bifunctional inhibitor/lipid-transfer protein/seed storage 2S albumin
View Download 0.361 a.24.4 Hemerythrin
View Download 0.360 a.45.1 Glutathione S-transferase (GST), C-terminal domain
View Download 0.360 a.24.17 Group V grass pollen allergen
View Download 0.358 a.45.1 Glutathione S-transferase (GST), C-terminal domain
View Download 0.355 d.55.1 Ribosomal protein L22
View Download 0.354 d.92.1 Metalloproteases ("zincins"), catalytic domain
View Download 0.353 d.58.20 NAD-binding domain of HMG-CoA reductase
View Download 0.349 a.47.2 t-snare proteins
View Download 0.345 a.29.3 Acyl-CoA dehydrogenase C-terminal domain-like
View Download 0.344 a.7.1 Spectrin repeat
View Download 0.341 a.13.1 alpha-2-Macroglobulin receptor associated protein (RAP) domain 1
View Download 0.341 a.24.2 Aspartate receptor, ligand-binding domain
View Download 0.338 d.96.1 Tetrahydrobiopterin biosynthesis enzymes-like
View Download 0.334 a.47.1 STAT
View Download 0.333 a.7.5 Tubulin chaperone cofactor A
View Download 0.332 a.121.1 Tetracyclin repressor-like, C-terminal domain
View Download 0.332 f.1.4 Bcl-2 inhibitors of programmed cell death
View Download 0.331 a.7.3 Succinate dehydrogenase/fumarate reductase flavoprotein C-terminal domain
View Download 0.329 a.91.1 Regulator of G-protein signalling, RGS
View Download 0.328 a.24.13 Domain of the SRP/SRP receptor G-proteins
View Download 0.328 a.77.1 DEATH domain
View Download 0.327 a.25.1 Ferritin-like
View Download 0.322 a.71.2 Helical domain of Sec23/24
View Download 0.320 d.122.1 ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase
View Download 0.319 a.1.1 Globin-like
View Download 0.318 a.24.13 Domain of the SRP/SRP receptor G-proteins
View Download 0.309 f.15.1 Small-conductance potassium channel
View Download 0.306 a.149.1 RNase III endonuclease catalytic domain
View Download 0.304 f.1.4 Bcl-2 inhibitors of programmed cell death
View Download 0.304 a.63.1 Apolipophorin-III
View Download 0.303 a.118.8 TPR-like
View Download 0.303 d.6.1 Prion-like
View Download 0.302 a.7.5 Tubulin chaperone cofactor A
View Download 0.301 d.75.2 DNA repair protein MutS, domain I
View Download 0.297 a.45.1 Glutathione S-transferase (GST), C-terminal domain
View Download 0.295 a.118.1 ARM repeat
View Download 0.294 a.118.12 Ran-GTPase activating protein 1 (RanGAP1), C-terminal domain
View Download 0.292 a.74.1 Cyclin-like
View Download 0.288 g.44.1 RING/U-box
View Download 0.281 a.71.2 Helical domain of Sec23/24
View Download 0.276 a.24.13 Domain of the SRP/SRP receptor G-proteins
View Download 0.273 d.96.1 Tetrahydrobiopterin biosynthesis enzymes-like
View Download 0.272 a.24.11 Bacterial GAP domain
View Download 0.271 a.126.1 Serum albumin-like
View Download 0.270 a.3.1 Cytochrome c
View Download 0.268 a.45.1 Glutathione S-transferase (GST), C-terminal domain
View Download 0.266 a.54.1 Domain of early E2A DNA-binding protein, ADDBP
View Download 0.265 a.29.3 Acyl-CoA dehydrogenase C-terminal domain-like
View Download 0.264 c.26.2 Adenine nucleotide alpha hydrolases-like
View Download 0.264 a.52.1 Bifunctional inhibitor/lipid-transfer protein/seed storage 2S albumin
View Download 0.260 a.7.3 Succinate dehydrogenase/fumarate reductase flavoprotein C-terminal domain
View Download 0.260 a.24.12 Outer surface protein C (OspC)
View Download 0.256 a.45.1 Glutathione S-transferase (GST), C-terminal domain
View Download 0.254 a.100.1 6-phosphogluconate dehydrogenase C-terminal domain-like
View Download 0.250 a.45.1 Glutathione S-transferase (GST), C-terminal domain
View Download 0.248 f.18.1 F1F0 ATP synthase subunit A
View Download 0.248 a.7.7 BAG domain
View Download 0.248 d.43.1 Elongation factor Ts (EF-Ts), dimerisation domain
View Download 0.242 a.7.4 Smac/diablo
View Download 0.242 a.29.5 alpha-ketoacid dehydrogenase kinase, N-terminal domain
View Download 0.240 a.126.1 Serum albumin-like
View Download 0.239 a.77.1 DEATH domain
View Download 0.234 a.47.2 t-snare proteins
View Download 0.233 a.26.1 4-helical cytokines
View Download 0.231 a.151.1 Glutamyl tRNA-reductase dimerization domain
View Download 0.223 c.97.1 Cytidine deaminase-like
View Download 0.221 a.149.1 RNase III endonuclease catalytic domain
View Download 0.220 a.27.1 Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases
View Download 0.213 b.88.1 Mss4-like
View Download 0.209 a.7.2 Enzyme IIa from lactose specific PTS, IIa-lac
View Download 0.209 a.48.2 Transferrin receptor ectodomain, C-terminal domain
View Download 0.207 a.60.6 DNA polymerase beta, N-terminal domain-like
View Download 0.206 a.74.1 Cyclin-like
View Download 0.203 f.35.1 Multidrug efflux transporter AcrB transmembrane domain

Predicted Domain #3
Region A:
Residues: [280-561]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 SSGMAFVVGL VNPIWAFVGI DSATHMIDEV GYSKSRFLVP KVIITTIIVG FVTSFIYCVG  60
   61 LFFCITDQTA VVESILPIVE IFYQATGNRN LSVFLQCMCI TTGFVSGIAS GTWQSRILQS 120
  121 FGKSYAPFYK EGSLGNKSLK KLAVLTPGFK SPLYAHFLSQ ICVTIIGCIF MGSSTAFNAI 180
  181 ITACITLLLM SYAVPSFIFL FVIKKEKFIH RIESDVNCVS RPNRRRMSMI PHIICILWTL 240
  241 FCLVFLSFPY TLPVTAGNMN YTSVVYAVVF CIISIVVFPT CI

[Run NCBI BLAST on this sequence.]

Detection Method: MSA

Shown below are all of our structure predictions for this domain.
Click here to view only most confident match.

Found no structure predictions for this domain.


YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle