YRC Public Data Repository - Protein Structure Prediction

Protein:	YNR029C
Organism:	Saccharomyces cerevisiae
Length:	429 amino acids
Reference:	Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for YNR029C.

Description	E-value	Query Range	Subject Range
YN8H_YEAST - Uncharacterized protein YNR029C OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=YNR029C ... YNR029C - Putative protein of unknown function, deletion confers reduced fitness in saline	0.0	[1..429]	[1..429]
gi\|11348350 - pir\|\|D82953 conserved hypothetical protein PA5535 [imported] - Pseudomonas aeruginosa (strain PAO1) gi\|9951874, gi\|1... - gi\|9951874\|gb\|AAG08920.1\|AE004966_2 conserved hypothetical protein [Pseudomonas aeruginosa PAO1], gi...	6.0E-95	[69..428]	[3..373]
YCIC_BACSU - Putative metal chaperone YciC OS=Bacillus subtilis (strain 168) GN=yciC PE=2 SV=1 gi\|221312473 - gi\|221312473\|ref\|ZP_03594278.1\| hypothetical protein BsubsN3_01886 [Bacillus subtilis subsp. subtili... gi\|221317406 - gi\|221317406\|ref\|ZP_03598700.1\| hypothetical protein BsubsJ_01873 [Bacillus subtilis subsp. subtilis... YCIC_BACSU - Putative metal chaperone YciC OS=Bacillus subtilis GN=yciC PE=2 SV=1 gi\|221321669 - gi\|221321669\|ref\|ZP_03602963.1\| hypothetical protein BsubsS_01904 [Bacillus subtilis subsp. subtilis...	9.0E-92	[68..428]	[1..374]
gi\|66392706, gi\|... - gi\|66392706\|emb\|CAG29811.1\| nitrile hydratase activator P44k [Rhodococcus erythropolis], gi\|23304614... gi\|10129794 - gi\|10129794\|emb\|CAC08207.1\| P44k protein [Rhodococcus sp. AJ270]	2.0E-91	[68..428]	[3..370]
gi\|15614353, gi\|... - gi\|15614353\|ref\|NP_242656.1\| hypothetical protein BH1790 [Bacillus halodurans C-125], gi\|10174408\|db... gi\|25315926 - pir\|\|F83873 hypothetical protein BH1790 [imported] - Bacillus halodurans (strain C-125)	2.0E-90	[70..428]	[5..372]
gi\|15160214, gi\|... - gi\|15891748\|ref\|NP_357420.1\| hypothetical protein AGR_L_3257 [Agrobacterium tumefaciens str. C58], g... gi\|25315936 - pir\|\|C98335 hypothetical protein AGR_L_3257 [imported] - Agrobacterium tumefaciens (strain C58, Cere...	3.0E-90	[67..428]	[31..405]
gi\|254698171 - gi\|254698171\|ref\|ZP_05159999.1\| cobalamin synthesis protein/P47K family protein [Brucella abortus bv... gi\|254731615 - gi\|254731615\|ref\|ZP_05190193.1\| cobalamin synthesis protein/P47K family protein [Brucella abortus bv... gi\|17988523, gi\|... - gi\|17988523\|ref\|NP_541156.1\| zinc transporter [Brucella melitensis 16M], gi\|17984316\|gb\|AAL53420.1\| ... gi\|83269917 - gi\|83269917\|ref\|YP_419208.1\| cobalamin synthesis protein P47K [Brucella melitensis biovar Abortus 23... gi\|237787320, gi... - gi\|237817485\|ref\|ZP_04596476.1\| cobalamin synthesis protein/P47K family protein [Brucella abortus st... gi\|254691630 - gi\|254691630\|ref\|ZP_05154884.1\| cobalamin synthesis protein/P47K family protein [Brucella abortus bv... gi\|82940191 - gi\|82940191\|emb\|CAJ13244.1\| ATP/GTP-binding site motif A (P-loop):Cobalamin synthesis protein/P47K [... gi\|25315940 - pir\|\|AI3531 low affinity zinc transport membrane protein [imported] - Brucella melitensis (strain 16... gi\|62317940, gi\|... - gi\|62317940\|ref\|YP_223793.1\| cobalamin synthesis protein/P47K family protein [Brucella abortus bv. 1... gi\|189021765, gi... - gi\|189023191\|ref\|YP_001932932.1\| Cobalamin synthesis protein/P47K [Brucella abortus S19], gi\|1890217... gi\|225686867, gi... - gi\|225686867\|ref\|YP_002734839.1\| cobalamin synthesis protein/P47K family protein [Brucella melitensi...	5.0E-88	[69..428]	[3..375]
gi\|15923440, gi\|... - gi\|15923440\|ref\|NP_370974.1\| putative cobalamin synthesis protein [Staphylococcus aureus subsp. aure... gi\|15926128, gi\|... - gi\|15926128\|ref\|NP_373661.1\| hypothetical protein SA0410 [Staphylococcus aureus subsp. aureus N315],... gi\|25315934 - pir\|\|D89810 conserved hypothetical protein SA0410 [imported] - Staphylococcus aureus (strain N315) gi\|149945407, gi... - gi\|90583968\|ref\|ZP_01239716.1\| Cobalamin synthesis protein/P47K:Cobalamin synthesis CobW, C-terminal... gi\|148266910, gi... - gi\|90586519\|ref\|ZP_01242214.1\| Cobalamin synthesis protein/P47K:Cobalamin synthesis CobW, C-terminal... gi\|253315050 - gi\|253315050\|ref\|ZP_04838263.1\| hypothetical protein SauraC_02538 [Staphylococcus aureus subsp. aure... gi\|255005246 - gi\|255005246\|ref\|ZP_05143847.2\| hypothetical protein SauraM_02225 [Staphylococcus aureus subsp. aure... gi\|156978779, gi... - gi\|156978779\|ref\|YP_001441038.1\| hypothetical protein SAHV_0448 [Staphylococcus aureus subsp. aureus... gi\|269202071\|ref... - cobalamin synthesis protein, putative [Staphylococcus aureus subsp. aureus ED98]	6.0E-87	[68..428]	[1..375]
gi\|216854\|dbj\|BA... - unnamed protein product [Pseudomonas chlororaphis] P47K_PSECL - 47 kDa protein OS=Pseudomonas chlororaphis PE=3 SV=1	6.0E-86	[64..428]	[3..379]

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Predicted Domain #1

Region A:
Residues: [1-65]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MSALRNIKFN EEEDGELPCL VTGEENNLQE ILENVSYDGG NIVSDAKVER VNKQVENTSA  60
   61 GATDV

[Run NCBI BLAST on this sequence.]

Detection Method:

deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted functions:

Term	Confidence	Notes
binding	1.41264401383678	bayes_pls_golite062009
catalytic activity	1.00104173493322	bayes_pls_golite062009
nucleic acid binding	0.736973987187739	bayes_pls_golite062009
RNA helicase activity	0.39531421511441	bayes_pls_golite062009
RNA-dependent ATPase activity	0.249558209438385	bayes_pls_golite062009
ATP-dependent RNA helicase activity	0.231952192863482	bayes_pls_golite062009
DNA binding	0.156173690421144	bayes_pls_golite062009
nucleotide binding	0.114848452385726	bayes_pls_golite062009
purine nucleotide binding	0.10713474095071	bayes_pls_golite062009
purine ribonucleotide binding	0.0916519414118148	bayes_pls_golite062009
ribonucleotide binding	0.0915913646217636	bayes_pls_golite062009

Predicted Domain #2

Region A:
Residues: [66-315]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 HEKKRIPVSI ITGYLGSGKS TLLEKIALKG ADKKIAVILN EFGDSSEIEK AMTIKNGSNS  60
   61 YQEWLDLGNG CLCCSLKNIG VKAIEDMVER SPGKIDYILL ETSGIADPAP IAKMFWQDEG 120
  121 LNSSVYIDGI ITVLDCEHIL KCLDDISIDA HWHGDKVGLE GNLTIAHFQL AMADRIIMNK 180
  181 YDTIEHSPEM VKQLKERVRE INSIAPMFFT KYSDTPIQNL LDIHAYDSVR ISDILDSGSG 240
  241 NGTIHDDRMG

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	2.09691
Match:	2ffhA_
Description:	Signal sequence recognition protein Ffh; Signal sequence binding protein Ffh; GTPase domain of the signal sequence recognition protein Ffh
Matching Structure (courtesy of the PDB):

Predicted Domain #3

Region A:
Residues: [316-429]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 TIMLTFRPLK NEEEYNNKFI KQFLQPLLWK NFGAMTVLGG RRRDDGRDWE VQRTKGLILI  60
   61 EGENPIARVI QGVRDTYDVF PGKYDGSNKE CKIVLIGKYL EKESIEELLR KTLE

[Run NCBI BLAST on this sequence.]

Detection Method:

MSA

Shown below is our most confident prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits

Predicted functions: