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View Structure Prediction Details

Protein: LRO1
Organism: Saccharomyces cerevisiae
Length: 661 amino acids
Reference: Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for LRO1.

Description E-value Query
Range
Subject
Range
PDAT_YEAST - Phospholipid:diacylglycerol acyltransferase OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c)...
LRO1 - Acyltransferase that catalyzes diacylglycerol esterification; one of several acyltransferases that c...
gi|190408991 - gi|190408991|gb|EDV12256.1| phospholipid:diacylglycerol acyltransferase [Saccharomyces cerevisiae RM...
0.0 [1..661] [1..661]
plh1 - phospholipid-diacylglycerol acyltransferase Plh1
PDAT_SCHPO - Phospholipid:diacylglycerol acyltransferase OS=Schizosaccharomyces pombe (strain 972 / ATCC 24843) G...
0.0 [69..657] [46..616]
PDAT1_ARATH - Phospholipid:diacylglycerol acyltransferase 1 OS=Arabidopsis thaliana GN=PDAT1 PE=2 SV=1
0.0 [156..657] [92..667]
gi|386858 - gi|386858|gb|AAA59500.1| lecithin-cholesterol acyltransferase precursor (EC 2.3.1.43) [Homo sapiens]
0.0 [159..644] [21..418]
gi|158262015, gi... - gi|60688171|gb|AAH91155.1| Lecithin cholesterol acyltransferase [Rattus norvegicus], gi|2306762|gb|A...
0.0 [159..644] [33..430]
LCAT_PAPAN - Phosphatidylcholine-sterol acyltransferase OS=Papio anubis GN=LCAT PE=2 SV=1
gi|483302 - gi|483302|pir||JC1502 phosphatidylcholine-sterol O-acyltransferase (EC 2.3.1.43) precursor - baboon
0.0 [159..643] [33..429]

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Predicted Domain #1
Region A:
Residues: [1-125]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MGTLFRRNVQ NQKSDSDENN KGGSVHNKRE SRNHIHHQQG LGHKRRRGIS GSAKRNERGK  60
   61 DFDRKRDGNG RKRWRDSRRL IFILGAFLGV LLPFSFGAYH VHNSDSDLFD NFVNFDSLKV 120
  121 YLDDW

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #2
Region A:
Residues: [126-221]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 KDVLPQGISS FIDDIQAGNY STSSLDDLSE NFAVGKQLLR DYNIEAKHPV VMVPGVISTG  60
   61 IESWGVIGDD ECDSSAHFRK RLWGSFYMLR TMVMDK

[Run NCBI BLAST on this sequence.]

Detection Method: MSA

Shown below is our most confident prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #3
Region A:
Residues: [222-392]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 VCWLKHVMLD PETGLDPPNF TLRAAQGFES TDYFIAGYWI WNKVFQNLGV IGYEPNKMTS  60
   61 AAYDWRLAYL DLERRDRYFT KLKEQIELFH QLSGEKVCLI GHSMGSQIIF YFMKWVEAEG 120
  121 PLYGNGGRGW VNEHIDSFIN AAGTLLGAPK AVPALISGEM KDTIQLNTLA M

[Run NCBI BLAST on this sequence.]

Detection Method: ORFEUS
Confidence: 9.89
Match: 1ex9A
Description: Lipase
Matching Structure (courtesy of the PDB):

Predicted Domain #4
Region A:
Residues: [393-602]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 YGLEKFFSRI ERVKMLQTWG GIPSMLPKGE EVIWGDMKSS SEDALNNNTD TYGNFIRFER  60
   61 NTSDAFNKNL TMKDAINMTL SISPEWLQRR VHEQYSFGYS KNEEELRKNE LHHKHWSNPM 120
  121 EVPLPEAPHM KIYCIYGVNN PTERAYVYKE EDDSSALNLT IDYESKQPVF LTEGDGTVPL 180
  181 VAHSMCHKWA QGASPYNPAG INVTIVEMKH 

[Run NCBI BLAST on this sequence.]

Detection Method: MSA

Shown below is our most confident prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #5
Region A:
Residues: [603-661]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 QPDRFDIRGG AKSAEHVDIL GSAELNDYIL KIASGNGDLV EPRQLSNLSQ WVSQMPFPM

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.


YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle