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View Structure Prediction Details

Protein: LRO1
Organism: Saccharomyces cerevisiae
Length: 661 amino acids
Reference: Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for LRO1.

Description E-value Query
Range
Subject
Range
PDAT_YEAST - Phospholipid:diacylglycerol acyltransferase OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c)...
LRO1 - Acyltransferase that catalyzes diacylglycerol esterification; one of several acyltransferases that c...
gi|190408991 - gi|190408991|gb|EDV12256.1| phospholipid:diacylglycerol acyltransferase [Saccharomyces cerevisiae RM...
0.0 [1..661] [1..661]
plh1 - phospholipid-diacylglycerol acyltransferase Plh1
PDAT_SCHPO - Phospholipid:diacylglycerol acyltransferase OS=Schizosaccharomyces pombe (strain 972 / ATCC 24843) G...
0.0 [69..657] [46..616]
PDAT1_ARATH - Phospholipid:diacylglycerol acyltransferase 1 OS=Arabidopsis thaliana GN=PDAT1 PE=2 SV=1
0.0 [156..657] [92..667]
gi|386858 - gi|386858|gb|AAA59500.1| lecithin-cholesterol acyltransferase precursor (EC 2.3.1.43) [Homo sapiens]
0.0 [159..644] [21..418]
gi|158262015, gi... - gi|60688171|gb|AAH91155.1| Lecithin cholesterol acyltransferase [Rattus norvegicus], gi|2306762|gb|A...
0.0 [159..644] [33..430]
LCAT_PAPAN - Phosphatidylcholine-sterol acyltransferase OS=Papio anubis GN=LCAT PE=2 SV=1
gi|483302 - gi|483302|pir||JC1502 phosphatidylcholine-sterol O-acyltransferase (EC 2.3.1.43) precursor - baboon
0.0 [159..643] [33..429]

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Predicted Domain #1
Region A:
Residues: [1-125]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MGTLFRRNVQ NQKSDSDENN KGGSVHNKRE SRNHIHHQQG LGHKRRRGIS GSAKRNERGK  60
   61 DFDRKRDGNG RKRWRDSRRL IFILGAFLGV LLPFSFGAYH VHNSDSDLFD NFVNFDSLKV 120
  121 YLDDW

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below are all of our de novo (Rosetta) predictions for this domain.
Click here to view only most confident match.

    MCM
Score
SCOP
Match
SCOP Description
View Download 0.443 c.13.2 Anti-sigma factor antagonist SpoIIaa

Predicted Domain #2
Region A:
Residues: [126-221]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 KDVLPQGISS FIDDIQAGNY STSSLDDLSE NFAVGKQLLR DYNIEAKHPV VMVPGVISTG  60
   61 IESWGVIGDD ECDSSAHFRK RLWGSFYMLR TMVMDK

[Run NCBI BLAST on this sequence.]

Detection Method: MSA

Shown below are all of our structure predictions for this domain.
Click here to view only most confident match.

    MCM
Score
GO
Score
GO
Term
SCOP
Match
SCOP Description
View Download 0.692 0.020 endoplasmic reticulum a.74.1 Cyclin-like
View Download 0.600 N/A N/A a.74.1 Cyclin-like
View Download 0.500 N/A N/A a.29.4 RecG, N-terminal domain
View Download 0.438 N/A N/A a.24.9 alpha-catenin/vinculin
View Download 0.435 N/A N/A a.80.1 DNA polymerase III clamp loader subunits, C-terminal domain
View Download 0.433 N/A N/A d.202.1 Transcription factor NusA, N-terminal domain
View Download 0.419 N/A N/A d.58.44 Multidrug efflux transporter AcrB pore domain; PN1, PN2, PC1 and PC2 subdomains
View Download 0.396 N/A N/A a.24.4 Hemerythrin
View Download 0.394 N/A N/A a.24.3 Cytochromes
View Download 0.367 N/A N/A a.69.3 1-deoxy-D-xylulose-5-phosphate reductoisomerase, C-terminal domain
View Download 0.349 N/A N/A a.71.2 Helical domain of Sec23/24
View Download 0.349 N/A N/A a.19.1 Fertilization protein
View Download 0.325 N/A N/A a.24.13 Domain of the SRP/SRP receptor G-proteins
View Download 0.317 N/A N/A a.13.1 alpha-2-Macroglobulin receptor associated protein (RAP) domain 1
View Download 0.312 N/A N/A a.2.11 Fe,Mn superoxide dismutase (SOD), N-terminal domain
View Download 0.307 N/A N/A d.55.1 Ribosomal protein L22
View Download 0.304 N/A N/A a.24.13 Domain of the SRP/SRP receptor G-proteins
View Download 0.303 N/A N/A d.14.1 Ribosomal protein S5 domain 2-like
View Download 0.291 N/A N/A a.72.1 Functional domain of the splicing factor Prp18
View Download 0.277 N/A N/A d.41.2 Quinolinic acid phosphoribosyltransferase (Nicotinate-nucleotide pyrophosphorylase, NadC), N-terminal domain
View Download 0.272 N/A N/A a.11.2 Second domain of FERM
View Download 0.269 N/A N/A a.77.1 DEATH domain
View Download 0.254 N/A N/A a.78.1 Fatty acid responsive transcription factor FadR, C-terminal domain
View Download 0.252 N/A N/A d.58.7 RNA-binding domain, RBD
View Download 0.244 N/A N/A a.181.1 Antibiotic binding domain of TipA-like multidrug resistance regulators
View Download 0.244 N/A N/A a.24.16 Nucleotidyltransferase substrate binding subunit/domain
View Download 0.243 N/A N/A a.118.11 Cytochrome c oxidase subunit E
View Download 0.242 N/A N/A d.53.1 Ribosomal protein S3 C-terminal domain
View Download 0.236 N/A N/A a.7.1 Spectrin repeat
View Download 0.233 N/A N/A a.1.1 Globin-like
View Download 0.231 N/A N/A c.30.1 PreATP-grasp domain
View Download 0.218 N/A N/A a.24.14 FAT domain of focal adhesion kinase
View Download 0.216 N/A N/A d.29.1 Ribosomal protein L31e
View Download 0.213 N/A N/A d.52.5 Probable GTPase Der, C-terminal domain
View Download 0.212 N/A N/A d.58.14 Ribosomal protein S6
View Download 0.201 N/A N/A a.24.3 Cytochromes
View Download 0.200 N/A N/A a.73.1 Retrovirus capsid protein, N-terminal core domain

Predicted Domain #3
Region A:
Residues: [222-392]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 VCWLKHVMLD PETGLDPPNF TLRAAQGFES TDYFIAGYWI WNKVFQNLGV IGYEPNKMTS  60
   61 AAYDWRLAYL DLERRDRYFT KLKEQIELFH QLSGEKVCLI GHSMGSQIIF YFMKWVEAEG 120
  121 PLYGNGGRGW VNEHIDSFIN AAGTLLGAPK AVPALISGEM KDTIQLNTLA M

[Run NCBI BLAST on this sequence.]

Detection Method: ORFEUS
Confidence: 9.89
Match: 1ex9A
Description: Lipase
Matching Structure (courtesy of the PDB):

Predicted Domain #4
Region A:
Residues: [393-602]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 YGLEKFFSRI ERVKMLQTWG GIPSMLPKGE EVIWGDMKSS SEDALNNNTD TYGNFIRFER  60
   61 NTSDAFNKNL TMKDAINMTL SISPEWLQRR VHEQYSFGYS KNEEELRKNE LHHKHWSNPM 120
  121 EVPLPEAPHM KIYCIYGVNN PTERAYVYKE EDDSSALNLT IDYESKQPVF LTEGDGTVPL 180
  181 VAHSMCHKWA QGASPYNPAG INVTIVEMKH 

[Run NCBI BLAST on this sequence.]

Detection Method: MSA

Shown below are all of our structure predictions for this domain.
Click here to view only most confident match.

Found no structure predictions for this domain.

Predicted Domain #5
Region A:
Residues: [603-661]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 QPDRFDIRGG AKSAEHVDIL GSAELNDYIL KIASGNGDLV EPRQLSNLSQ WVSQMPFPM

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below are all of our de novo (Rosetta) predictions for this domain.
Click here to view only most confident match.

    MCM
Score
SCOP
Match
SCOP Description
View Download 0.644 a.4.1 Homeodomain-like
View Download 0.509 a.60.2 RuvA domain 2-like
View Download 0.640 a.60.3 C-terminal domain of RNA polymerase alpha subunit
View Download 0.486 a.4.5 "Winged helix" DNA-binding domain
View Download 0.474 a.64.2 Bacteriocin AS-48
View Download 0.442 a.60.2 RuvA domain 2-like
View Download 0.355 a.144.2 Ribosomal protein L20
View Download 0.342 a.159.1 Protein serine/threonine phosphatase 2C, C-terminal domain
View Download 0.328 d.186.1 Head-to-tail joining protein W, gpW
View Download 0.321 d.42.1 POZ domain
View Download 0.318 a.28.1 ACP-like
View Download 0.307 a.2.2 Ribosomal protein L29 (L29p)
View Download 0.297 a.164.1 C-terminal domain of DFF45/ICAD (DFF-C domain)
View Download 0.293 a.4.1 Homeodomain-like
View Download 0.288 a.4.1 Homeodomain-like
View Download 0.284 a.4.5 "Winged helix" DNA-binding domain
View Download 0.272 a.140.4 Recombination endonuclease VII, C-terminal and dimerization domains
View Download 0.268 a.140.2 SAP domain
View Download 0.263 a.4.5 "Winged helix" DNA-binding domain
View Download 0.248 b.48.1 mu transposase, C-terminal domain
View Download 0.238 a.4.1 Homeodomain-like
View Download 0.214 a.23.5 Hemolysin expression modulating protein HHA
View Download 0.212 a.38.1 Helix-loop-helix DNA-binding domain
View Download 0.210 b.71.1 Glycosyl hydrolase domain
View Download 0.207 a.3.1 Cytochrome c
View Download 0.201 b.5.1 alpha-Amylase inhibitor tendamistat
View Download 0.201 a.35.1 lambda repressor-like DNA-binding domains


YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle