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View Structure Prediction Details

Protein: YNL313C
Organism: Saccharomyces cerevisiae
Length: 904 amino acids
Reference: Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for YNL313C.

Description E-value Query
Range
Subject
Range
YNL313C - Essential protein of unknown function; fluorescent protein (GFP or YFP)-tagged protein localizes to ...
EMW1_YEAST - Essential for maintenance of the cell wall protein 1 OS=Saccharomyces cerevisiae (strain ATCC 204508...
0.0 [1..904] [1..904]
gi|14042340 - gi|14042340|dbj|BAB55206.1| unnamed protein product [Homo sapiens]
0.0 [19..904] [30..822]
gi|15237943, gi|... - gi|15237943|ref|NP_197229.1| tetratricopeptide repeat (TPR)-containing protein [Arabidopsis thaliana...
3.0E-92 [10..897] [48..876]
gi|7459521, gi|1... - pir||B70126 surface-located membrane protein 1 (lmp1) homolog - Lyme disease spirochete, gi|13324590...
gi|15594555, gi|... - gi|2688100|gb|AAC66595.1| surface-located membrane protein 1 (lmp1) [Borrelia burgdorferi B31], gi|1...
5.0E-91 [11..817] [326..1102]
gi|13324596 - gi|13324596|gb|AAK18801.1|AF305609_1 LMP1 [Borrelia burgdorferi]
8.0E-87 [11..817] [326..1156]

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Predicted Domain #1
Region A:
Residues: [1-105]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 METLLHAKLL LSAEVESLKS GSFDQTYVKK AEHIISGESY QLVQQFVDKF KGKISISGEI  60
   61 STSSVIAALN DFLNVEVFKM GQENEMLFLA IALLQTFIQN NYTGP

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below are all of our de novo (Rosetta) predictions for this domain.
Click here to view only most confident match.

    MCM
Score
SCOP
Match
SCOP Description
View Download 0.463 a.2.11 Fe,Mn superoxide dismutase (SOD), N-terminal domain
View Download 0.443 a.65.1 Annexin
View Download 0.549 a.61.1 Retroviral matrix proteins
View Download 0.439 a.61.1 Retroviral matrix proteins
View Download 0.437 c.55.6 DNA repair protein MutS, domain II
View Download 0.398 d.50.1 dsRNA-binding domain-like
View Download 0.393 a.142.1 PTS-regulatory domain, PRD
View Download 0.391 a.4.5 "Winged helix" DNA-binding domain
View Download 0.374 a.24.9 alpha-catenin/vinculin
View Download 0.371 a.73.1 Retrovirus capsid protein, N-terminal core domain
View Download 0.357 a.73.1 Retrovirus capsid protein, N-terminal core domain
View Download 0.353 a.73.1 Retrovirus capsid protein, N-terminal core domain
View Download 0.336 a.151.1 Glutamyl tRNA-reductase dimerization domain
View Download 0.333 a.39.1 EF-hand
View Download 0.329 a.73.1 Retrovirus capsid protein, N-terminal core domain
View Download 0.324 a.121.1 Tetracyclin repressor-like, C-terminal domain
View Download 0.308 a.1.1 Globin-like
View Download 0.304 a.4.5 "Winged helix" DNA-binding domain
View Download 0.303 a.3.1 Cytochrome c
View Download 0.292 a.4.5 "Winged helix" DNA-binding domain
View Download 0.291 c.49.1 Pyruvate kinase, C-terminal domain
View Download 0.279 d.108.1 Acyl-CoA N-acyltransferases (Nat)
View Download 0.274 d.14.1 Ribosomal protein S5 domain 2-like
View Download 0.271 a.142.1 PTS-regulatory domain, PRD
View Download 0.261 d.43.1 Elongation factor Ts (EF-Ts), dimerisation domain
View Download 0.257 a.1.1 Globin-like
View Download 0.257 a.142.1 PTS-regulatory domain, PRD
View Download 0.256 a.78.1 Fatty acid responsive transcription factor FadR, C-terminal domain
View Download 0.248 a.24.17 Group V grass pollen allergen
View Download 0.238 a.25.2 Thermoplasma ferritin-like 4-helical bundle
View Download 0.238 a.112.1 Description not found.
View Download 0.233 a.80.1 DNA polymerase III clamp loader subunits, C-terminal domain
View Download 0.226 a.159.1 Protein serine/threonine phosphatase 2C, C-terminal domain
View Download 0.226 a.1.1 Globin-like
View Download 0.222 d.6.1 Prion-like
View Download 0.221 i.11.1 Computational models partly based on NMR data
View Download 0.219 a.80.1 DNA polymerase III clamp loader subunits, C-terminal domain
View Download 0.216 a.24.7 FKBP12-rapamycin-binding domain of FKBP-rapamycin-associated protein (FRAP)
View Download 0.216 a.52.1 Bifunctional inhibitor/lipid-transfer protein/seed storage 2S albumin
View Download 0.216 a.24.4 Hemerythrin
View Download 0.213 a.24.13 Domain of the SRP/SRP receptor G-proteins
View Download 0.210 a.56.1 CO dehydrogenase ISP C-domain like
View Download 0.209 a.4.1 Homeodomain-like
View Download 0.206 a.118.13 Arp2/3 complex 16 kDa subunit ARPC5
View Download 0.205 a.26.1 4-helical cytokines
View Download 0.204 a.80.1 DNA polymerase III clamp loader subunits, C-terminal domain
View Download 0.202 e.20.1 Heat shock protein 70kD (HSP70), C-terminal substrate-binding fragment
View Download 0.201 a.79.1 Antitermination factor NusB
View Download 0.200 a.121.1 Tetracyclin repressor-like, C-terminal domain

Predicted Domain #2
Region A:
Residues: [106-485]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 AARLKAISGL FGKTGIEIGA VNTALSRSLA IMGQPAYEFM DDPLYLVLSL LLLERITGQK  60
   61 SLFDVTPDQE IPLPIISAES TPGLLAVAYW WWARALLTQL SLIPEPSGFQ ASVASAIYQS 120
  121 ADLAYAITKE LPESIHEDFK RELCAMYYLE NVKCSLAINT EHLCLPSLTR AKKITNFEFV 180
  181 MTGARATRTK YQQKAHAGLI ILAKSFTFQN FALRTTSATP ETFALESDLL LEKPHFESIA 240
  241 DEPLDEQIYS KRQKVDLNEG YEEDKLLPLA LRQENIPKLL LDLNPNDQPT LSDYDNIQLL 300
  301 LRLYTIKNTT PAKDPLVEEE LTALLSRILY QNGDKNWSIF ARSLWERSII ETTKAKTIER 360
  361 GLLQMQSLVE ELDLKIKSKL 

[Run NCBI BLAST on this sequence.]

Detection Method: MSA

Shown below are all of our structure predictions for this domain.
Click here to view only most confident match.

Found no structure predictions for this domain.

Predicted Domain #3
Region A:
Residues: [486-563]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 VPSSSEINVA SRLSYIHQLP FIPRWQLDAT LAEKYMSLGI LKSAVEIYER LGMACETALC  60
   61 YAAVGDEKKA EEILLQRI

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 5.0
Match: 1b89A_
Description: Clathrin heavy chain proximal leg segment
Matching Structure (courtesy of the PDB):

Predicted Domain #4
Region A:
Residues: [564-685]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 NENDSDARAY SILGDIKQDP SLWEKSWEIG KYVNAKNSLA KYYFNPPPKS GAQPNYSATL  60
   61 KHLNDSLRQY PLSFETWYFY GCVGLQCGKM QIAAEAFTRC VSLDPYHALS WSNLSAAYTK 120
  121 MD

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 38.221849
Match: 1fchA_
Description: Peroxin pex5 (peroxisomal targeting signal 1 (PTS1) receptor)
Matching Structure (courtesy of the PDB):

Predicted Domain #5
Region A:
Residues: [686-760]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 KLKEAYSCLK RAISCDAQKN WKIWENYMLV AVKLNEWEDV LTACKQLVSI RRDKSGEGSI  60
   61 DLPIIEKLVE LLVTS

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 38.221849
Match: 1fchA_
Description: Peroxin pex5 (peroxisomal targeting signal 1 (PTS1) receptor)
Matching Structure (courtesy of the PDB):

Predicted Domain #6
Region A:
Residues: [761-832]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 EYPEEPQQLS YFQKSCTEFI CNTLPQVITT SARCWRLVAR VELWRKRPWA ALECHEKAYR  60
   61 AISHNPDLEV EE

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 38.221849
Match: 1fchA_
Description: Peroxin pex5 (peroxisomal targeting signal 1 (PTS1) receptor)
Matching Structure (courtesy of the PDB):

Predicted Domain #7
Region A:
Residues: [833-904]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 KVWNDTVDAC EDLVAAYESL GEMEGKYGPG SLVCKDWKYK CRSTIKALMS KGKGRWDDSP  60
   61 GWDRLVEARS QI

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 38.221849
Match: 1fchA_
Description: Peroxin pex5 (peroxisomal targeting signal 1 (PTS1) receptor)
Matching Structure (courtesy of the PDB):

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle