YRC Logo
PROTEIN SEARCH:
Descriptions Names[Advanced Search]

View Structure Prediction Details

Protein: MON2
Organism: Saccharomyces cerevisiae
Length: 1636 amino acids
Reference: Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076



[What does the above image mean?]


[Show Ginzu Version Information]


Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for MON2.

Description E-value Query
Range		 Subject
Range
MON2 - Peripheral membrane protein with a role in endocytosis and vacuole integrity, interacts with Arl1p a...
gi|207341960 - gi|207341960|gb|EDZ69873.1| YNL297Cp-like protein [Saccharomyces cerevisiae AWRI1631]
MON2_YEAST - Protein MON2 OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=MON2 PE=1 SV=1
 0.0 [1..1636] [1..1636]
gi|44983299 - gi|44983299|gb|AAS52481.1| AEL204Cp [Ashbya gossypii ATCC 10895]
gi|44983299, gi|... - gi|45190403|ref|NP_984657.1| AEL204Cp [Ashbya gossypii ATCC 10895], gi|44983299|gb|AAS52481.1| AEL20...
 0.0 [1..1635] [1..1589]
SPAC23D3.13c - guanyl-nucleotide exchange factor
MON2_SCHPO - Protein MON2 homolog OS=Schizosaccharomyces pombe (strain 972 / ATCC 24843) GN=mon2 PE=1 SV=1
 0.0 [10..1577] [2..1568]
gi|15241106 - gi|15241106|ref|NP_198149.1| binding [Arabidopsis thaliana]
 0.0 [11..1612] [3..1598]
mon-2 - status:Partially_confirmed UniProt:Q19338 protein_id:CAA92830.1
 0.0 [1..1627] [1..1626]
BIG1_BOVIN - Brefeldin A-inhibited guanine nucleotide-exchange protein 1 OS=Bos taurus GN=ARFGEF1 PE=1 SV=1
 0.0 [360..1376] [837..1713]
gi|225000702 - gi|225000702|gb|AAI72243.1| ADP-ribosylation factor guanine nucleotide-exchange factor 1(brefeldin A...
ARFGEF1 - ADP-ribosylation factor guanine nucleotide-exchange factor 1(brefeldin A-inhibited)
 0.0 [360..1376] [837..1713]

Back

Predicted Domain #1
Region A:
Residues: [1-220] 
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MAMNTGGFDS MQRQLEAELR SLSSESKRRN STIRHASDKS IEILKRVHSF EELERHPDFA  60
   61 LPFVLACQSR NAKMTTLAMQ CLQGLSTVPS IPRSRLSEIL DAFIEATHLA MEIQLKVLQV 120
  121 VPIFFKTYGK FIYGPLCKKL LLCCSNLLHV PNKAPVVVGT ASATLQQLID EIFDRLSIES 180
  181 VVDDKQYEVL ISNSESIKVN VYRYDANKLF DNICSLNEIS

[Run NCBI BLAST on this sequence.]

Detection Method: MSA

Shown below is our most confident prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #2
Region A:
Residues: [221-326] 
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 SNGAVSDEEM LLDIGDIPID YGLEILESIL KNSQKNLLEC QDLQYLLRVK AIPLLLRCIS  60
   61 SSRHFSTAVR SCRCLKLLIR KEYLSILELE LEVILSLLIH GISVES

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

    MCM
Score		 GO
Score		 GO
Term		 SCOP
Match		 SCOP Description
View Download 0.855 0.039 protein targeting to vacuole a.27.1 Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases

Predicted Domain #3
Region A:
Residues: [327-1393] 
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 NLSGWQRVLS LELFKDLSQD PEIVNTLYMD YDNYPDKKHV FKYLLKECIV LLNSPEYITF  60
   61 LAPSKVVEKM DSPLITTENS TVKTKFMHLL DKSNAPSINI TYIISLILTI CNHLCEGLNK 120
  121 SALESSPLEK KIEDKEREEG TGNDSTVVKV YSGLFSGLFE LNKLFLYSTS LETSIFHLVV 180
  181 RAFQKLAHSA GVLSLKDKLR ACMKLFSILI TNNVTSSNQY SFNDTSKSAK NQHTRNISTS 240
  241 SVTTSPVEST KNPSRSIADS AQNKEMKRRL HPRNISSRQV SLLRALISLS ISLGPIFDSE 300
  301 SWRYTFLTWQ WITYYIYGPS ADFKESFYSE DIPPPPILTK SDVTSIESSL TKFFESTSSY 360
  361 SCSTFHLVLT RLILDSKNTL TLEQTNLNLN NDIGYHPLDA KDEIIPCIYN KAFFVNKIGE 420
  421 LATYNCKKFL FGKNGKELWS LISTYMIKLI SNREMDNDSL RLYTVRVFTD IIKKATNEVG 480
  481 NSDEQDNKVK QFGTLENLVI DSLMATINSI KQLDIGKQEI YNGTINVESD ILFQLLLTLK 540
  541 EILNEFGELL MNSWTNIFNI INSPFEWTVE DTDFSVNEDI DDSSLFEGIV QKHKNMIQVS 600
  601 YDVFKLISDD FLQSLPMSVI KFVIDTLVNF VSQKRNLNIS FSSISQFWLV GDYLRVRFNP 660
  661 ETLNLSDEKR RSLSEKINNQ KLIEIITSSS SHDWELYNGL WIYLLKNLIN CTNDDRVEVK 720
  721 NGAVQTFFRI IDSHSVCFPP WDLIFLEVIE PLLTKEWSTE ELENETDFIN VTLQGLIKLY 780
  781 PEHFKDFKNN TTCAKEWSML LDFLKRLLSS TSNNTKNAVI LNYQTLLKEI ITIEDVPSDI 840
  841 LKKCCEIFTD YNITYSDLST NASSKTEYDC IYELITGFPP LYQLISKYDA MTDEFVEKVL 900
  901 LLFNSAIKYP LLPEFVQDKT KPSSMQKAIL SGLDIFMTND SKDTEILILL QLSTISILAF 960
  961 DTREKITKKL GPKLPKASLN RLPTFEAISY MSCSNLRNRI AKIDQFGIST LKAKHILRIL1020
 1021 KNLAEIIKRK SLITGSESDE IPIWVLASNC FCDLSNKIFK SLQEDAE

[Run NCBI BLAST on this sequence.]

Detection Method: MSA

Shown below is our most confident prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #4
Region A:
Residues: [1394-1636] 
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 NPLKDNFCDL FINVIVVTLQ RINPELDNLT EIDDLNEYSK YREILLENRI IDLFNERQLD  60
   61 TFIYAVWDCS FLYEFDELEN ALMQDCGTFS ELSQKLSSFD FSCIFGSTTN PRFQTKYKCS 120
  121 LECLQDLVNF MLNTNEKLRK LTAPYLSARI ALALRRYISD EYLIGRAPIP KLRKTELATL 180
  181 LNGLCVILRG VLDQNSTLGN KQIGVENLQT LSPLILRTIP VSHKMDGLQD KVLELSLGFT 240
  241 KLD

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #5
Region A:
Residues: [663-782] 
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 ILTKSDVTSI ESSLTKFFES TSSYSCSTFH LVLTRLILDS KNTLTLEQTN LNLNNDIGYH  60
   61 PLDAKDEIIP CIYNKAFFVN KIGELATYNC KKFLFGKNGK ELWSLISTYM IKLISNREMD 120
  121

[Run NCBI BLAST on this sequence.]

Detection Method: FFAS03
Confidence: 1.13
Match: 2ie3A
Description: No description for 2ie3A was found.

Predicted Domain #6
Region A:
Residues: [783-1559] 
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 NDSLRLYTVR VFTDIIKKAT NEVGNSDEQD NKVKQFGTLE NLVIDSLMAT INSIKQLDIG  60
   61 KQEIYNGTIN VESDILFQLL LTLKEILNEF GELLMNSWTN IFNIINSPFE WTVEDTDFSV 120
  121 NEDIDDSSLF EGIVQKHKNM IQVSYDVFKL ISDDFLQSLP MSVIKFVIDT LVNFVSQKRN 180
  181 LNISFSSISQ FWLVGDYLRV RFNPETLNLS DEKRRSLSEK INNQKLIEII TSSSSHDWEL 240
  241 YNGLWIYLLK NLINCTNDDR VEVKNGAVQT FFRIIDSHSV CFPPWDLIFL EVIEPLLTKE 300
  301 WSTEELENET DFINVTLQGL IKLYPEHFKD FKNNTTCAKE WSMLLDFLKR LLSSTSNNTK 360
  361 NAVILNYQTL LKEIITIEDV PSDILKKCCE IFTDYNITYS DLSTNASSKT EYDCIYELIT 420
  421 GFPPLYQLIS KYDAMTDEFV EKVLLLFNSA IKYPLLPEFV QDKTKPSSMQ KAILSGLDIF 480
  481 MTNDSKDTEI LILLQLSTIS ILAFDTREKI TKKLGPKLPK ASLNRLPTFE AISYMSCSNL 540
  541 RNRIAKIDQF GISTLKAKHI LRILKNLAEI IKRKSLITGS ESDEIPIWVL ASNCFCDLSN 600
  601 KIFKSLQEDA ENPLKDNFCD LFINVIVVTL QRINPELDNL TEIDDLNEYS KYREILLENR 660
  661 IIDLFNERQL DTFIYAVWDC SFLYEFDELE NALMQDCGTF SELSQKLSSF DFSCIFGSTT 720
  721 NPRFQTKYKC SLECLQDLVN FMLNTNEKLR KLTAPYLSAR IALALRRYIS DEYLIGR

[Run NCBI BLAST on this sequence.]

Detection Method: FFAS03
Confidence: 0.974
Match: 1w63A
Description: AP1 clathrin adaptor core
Matching Structure (courtesy of the PDB):

Predicted Domain #7
Region A:
Residues: [1560-1636] 
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 APIPKLRKTE LATLLNGLCV ILRGVLDQNS TLGNKQIGVE NLQTLSPLIL RTIPVSHKMD  60
   61 GLQDKVLELS LGFTKLD

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle