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View Structure Prediction Details

Protein: SEC21
Organism: Saccharomyces cerevisiae
Length: 935 amino acids
Reference: Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for SEC21.

Description E-value Query
Range
Subject
Range
COPG2_MOUSE - Coatomer subunit gamma-2 OS=Mus musculus GN=Copg2 PE=1 SV=1
0.0 [1..933] [1..870]
COPG2_TAKRU - Coatomer subunit gamma-2 OS=Takifugu rubripes GN=copg2 PE=3 SV=1
0.0 [1..933] [1..872]
gi|6179934, gi|1... - gi|6179934|gb|AAF05717.1|AF191561_1 coatomer protein gamma2-COP [Danio rerio], gi|18858453|ref|NP_57...
0.0 [1..933] [1..872]
COPG - coatomer protein complex, subunit gamma
0.0 [1..933] [1..873]
gi|1066165 - gi|1066165|emb|CAA63574.1| coat protein gamma-cop [Bos primigenius]
COPG1_BOVIN - Coatomer subunit gamma-1 OS=Bos taurus GN=COPG1 PE=1 SV=1
0.0 [1..933] [1..873]
gi|151944260 - gi|151944260|gb|EDN62539.1| non-clathrin coat protein [Saccharomyces cerevisiae YJM789]
gi|190409255 - gi|190409255|gb|EDV12520.1| PEST sequence-containing protein [Saccharomyces cerevisiae RM11-1a]
COPG_YEAST - Coatomer subunit gamma OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=SEC21 PE=1 SV=2
SEC21 - Gamma subunit of coatomer, a heptameric protein complex that together with Arf1p forms the COPI coat...
gi|207341949 - gi|207341949|gb|EDZ69865.1| YNL287Wp-like protein [Saccharomyces cerevisiae AWRI1631]
0.0 [1..935] [1..935]

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Predicted Domain #1
Region A:
Residues: [1-105]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MSAHTYKKFE NSTSGDLPDK MTIYQDCMNT FNESPVNSKR CRLLISRLLR LLAQGETFPQ  60
   61 NEATALFFSI SKLFQHQNDP LRQAVYLAIK ELSGISEDVL MATSS

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 115.70927
Match: 1gw5B_
Description: Adaptin beta subunit N-terminal fragment
Matching Structure (courtesy of the PDB):

Predicted Domain #2
Region A:
Residues: [106-213]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 IMKDVQNGSD LIKPDAIRSL TYVLDESTAF SAERLLKSAV VSRHPSISSA ALCTSYHLLP  60
   61 ISEVTIRRFT NETQEAVLDL KQFPNQHGNS EYYPNSTYIS QYHALGLL

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 115.70927
Match: 1gw5B_
Description: Adaptin beta subunit N-terminal fragment
Matching Structure (courtesy of the PDB):

Predicted Domain #3
Region A:
Residues: [214-357]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 YQLKKTDKMA LLKLVRHFSE NNSMKNQLAK VELVKIVNDL IYRDPQLFSQ FRPLLSDWLS  60
   61 NKFESVQLET AKLITSFATR NSRLVAPELY AAAISALQSL LTVPRVSSRF AALRILNRIS 120
  121 MVSPEKIVVC NPELESLIND SNRN

[Run NCBI BLAST on this sequence.]

Region B:
Residues: [579-650]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 IPSLESKLSS YISSNTDSFA TAFDVNQVRK FTEDEMKAIN LKRKQEQIFN QKSETTLDTT  60
   61 PEAESVPEKR AD

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 115.70927
Match: 1gw5B_
Description: Adaptin beta subunit N-terminal fragment
Matching Structure (courtesy of the PDB):

Predicted Domain #4
Region A:
Residues: [358-451]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 ISTYAITTLL KTGTSKNISS LISTITNFIH DVSDDFKIII IDAVRTLSLN FPQEWKSILN  60
   61 FLIDVLKNSE GGFKFKNSIV EALIDIVSFV PQSK

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 115.70927
Match: 1gw5B_
Description: Adaptin beta subunit N-terminal fragment
Matching Structure (courtesy of the PDB):

Predicted Domain #5
Region A:
Residues: [452-578]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 ELALENLCDF IEDCEFNEIL VRILHLLGKE GPSAPNPSLY VRHIYNRVVL ENSIIRSAAV  60
   61 VALSKFALTK NDPTLYESII SLLKRIANDK DDEVRDRATI ALEFIDSARN KDDVIAQNLI 120
  121 ESKYFYD

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 115.70927
Match: 1gw5B_
Description: Adaptin beta subunit N-terminal fragment
Matching Structure (courtesy of the PDB):

Predicted Domain #6
Region A:
Residues: [651-749]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 ANSFAGPNLD DHQEDLLATK YADELLSIEQ IKPFGQLVNS SRAISLTEPE AEFVVRGVKH  60
   61 LFKDNVVLQF NITNTLTDIA LDNVSVVCTP EISDEAELE

[Run NCBI BLAST on this sequence.]

Detection Method: MSA

Shown below are all of our structure predictions for this domain.
Click here to view only most confident match.

    MCM
Score
GO
Score
GO
Term
SCOP
Match
SCOP Description
View Download 0.515 0.493 retrograde vesicle-mediated transport, Golgi to ER c.47.1 Thioredoxin-like
View Download 0.469 0.089 retrograde vesicle-mediated transport, Golgi to ER b.43.4 Riboflavin synthase domain-like
View Download 0.467 0.028 retrograde vesicle-mediated transport, Golgi to ER d.129.1 TATA-box binding protein-like
View Download 0.562 N/A N/A d.50.2 Porphobilinogen deaminase (hydroxymethylbilane synthase), C-terminal domain
View Download 0.554 N/A N/A d.129.2 Phosphoglucomutase, C-terminal domain
View Download 0.467 N/A N/A d.51.1 Eukaryotic type KH-domain (KH-domain type I)
View Download 0.459 N/A N/A d.41.3 Pyrimidine nucleoside phosphorylase C-terminal domain
View Download 0.458 N/A N/A c.13.2 Anti-sigma factor antagonist SpoIIaa
View Download 0.450 N/A N/A d.17.1 Cystatin/monellin
View Download 0.410 N/A N/A d.129.1 TATA-box binding protein-like
View Download 0.394 N/A N/A d.129.2 Phosphoglucomutase, C-terminal domain
View Download 0.383 N/A N/A d.58.18 Regulatory domain in the aminoacid metabolism
View Download 0.379 N/A N/A b.61.3 D-aminopeptidase, middle and C-terminal domains
View Download 0.370 N/A N/A d.129.1 TATA-box binding protein-like
View Download 0.362 N/A N/A d.105.1 Clathrin adaptor appendage, alpha and beta chain-specific domain
View Download 0.360 N/A N/A c.47.2 RNA 3'-terminal phosphate cyclase, RPTC, insert domain
View Download 0.347 N/A N/A b.60.1 Lipocalins
View Download 0.343 N/A N/A d.50.2 Porphobilinogen deaminase (hydroxymethylbilane synthase), C-terminal domain
View Download 0.342 N/A N/A d.105.1 Clathrin adaptor appendage, alpha and beta chain-specific domain
View Download 0.320 N/A N/A d.15.6 Superantigen toxins, C-terminal domain
View Download 0.318 N/A N/A b.43.4 Riboflavin synthase domain-like
View Download 0.311 N/A N/A b.55.1 PH domain-like
View Download 0.310 N/A N/A d.105.1 Clathrin adaptor appendage, alpha and beta chain-specific domain
View Download 0.296 N/A N/A d.105.1 Clathrin adaptor appendage, alpha and beta chain-specific domain
View Download 0.296 N/A N/A d.110.3 PYP-like sensor domain (PAS domain)
View Download 0.294 N/A N/A a.60.2 RuvA domain 2-like
View Download 0.289 N/A N/A b.1.18 E set domains
View Download 0.288 N/A N/A c.51.1 Anticodon-binding domain of Class II aaRS
View Download 0.281 N/A N/A d.50.2 Porphobilinogen deaminase (hydroxymethylbilane synthase), C-terminal domain
View Download 0.276 N/A N/A c.23.1 CheY-like
View Download 0.256 N/A N/A d.105.1 Clathrin adaptor appendage, alpha and beta chain-specific domain
View Download 0.253 N/A N/A d.131.1 DNA clamp
View Download 0.247 N/A N/A c.47.1 Thioredoxin-like
View Download 0.243 N/A N/A d.24.1 Pili subunits
View Download 0.221 N/A N/A b.61.1 Avidin/streptavidin
View Download 0.221 N/A N/A d.129.2 Phosphoglucomutase, C-terminal domain
View Download 0.205 N/A N/A d.110.1 Profilin (actin-binding protein)
View Download 0.200 N/A N/A d.58.17 Metal-binding domain

Predicted Domain #7
Region A:
Residues: [750-935]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 ELFTLQVDRL LPSEEAACYV AFKKLDEIVM EGFLNNLTFT TKEINPDTNE PFDGDEGFQD  60
   61 EYEIDSIFLN AGDYVKSSFT GNFSATFDEL PCEEVAVFNI QEDLSIQEVV DKIILNSSCL 120
  121 PVESTQFAPS DSNSHTLKLF GKSALTGSKV ALQIKMIKSS KGLALKVHGK GEDSLLCSDL 180
  181 VNGLMQ

[Run NCBI BLAST on this sequence.]

Detection Method: MSA

Shown below are all of our structure predictions for this domain.
Click here to view only most confident match.

Found no structure predictions for this domain.


YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle