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View Structure Prediction Details

Protein: CAF120
Organism: Saccharomyces cerevisiae
Length: 1060 amino acids
Reference: Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for CAF120.

Description E-value Query
Range
Subject
Range
CAF120 - Part of the evolutionarily-conserved CCR4-NOT transcriptional regulatory complex involved in control...
CA120_YEAST - CCR4-NOT transcriptional complex subunit CAF120 OS=Saccharomyces cerevisiae (strain ATCC 204508 / S2...
0.0 [1..1060] [1..1060]
FP1_MYTCO - Adhesive plaque matrix protein OS=Mytilus coruscus GN=FP1 PE=2 SV=1
2.0E-49 [345..1057] [132..854]
SLP1_CLOTM, SLAP... - (Q06852) Cell surface glycoprotein 1 precursor (Outer layer protein B) (S-layer protein 1), Cell sur...
2.0E-47 [407..1019] [762..1367]
FP1_MYTGA - Adhesive plaque matrix protein OS=Mytilus galloprovincialis GN=FP1 PE=2 SV=1
1.0E-46 [386..1044] [44..692]
TCNA_TRYCR - Sialidase OS=Trypanosoma cruzi GN=TCNA PE=2 SV=1
7.0E-46 [506..1059] [590..1124]
FP1_MYTED - Adhesive plaque matrix protein (Fragment) OS=Mytilus edulis GN=FP1 PE=1 SV=1
2.0E-44 [281..1056] [53..830]
gi|15828996 - gi|15828996|ref|NP_326356.1| lipoprotein VSAC (fragment) [Mycoplasma pulmonis UAB CTIP]
gi|14089939, gi|... - pir||E90577 lipoprotein vsaC [imported] - Mycoplasma pulmonis (strain UAB CTIP) (fragment), gi|14089...
6.0E-44 [386..1059] [107..782]
gi|7507776 - gi|7507776|pir||T16867 probable cytochrome P450 T13C5.1 [similarity] - Caenorhabditis elegans
1.0E-42 [365..1059] [41..747]

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Predicted Domain #1
Region A:
Residues: [1-75]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MRIFSGDNKV VDSLASNPGL MSPSNFGGDF GSRLKVNVTS KKKLNDSSPT SPMESSPVSP  60
   61 ELVPILTLLN AHTHR

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted functions:

Term Confidence Notes
binding 3.16245771986829 bayes_pls_golite062009
transcription regulator activity 2.13588211069605 bayes_pls_golite062009
protein binding 1.95763087285706 bayes_pls_golite062009
nucleic acid binding 1.89560227697295 bayes_pls_golite062009
DNA binding 1.80618207914839 bayes_pls_golite062009
general RNA polymerase II transcription factor activity 1.7376876470681 bayes_pls_golite062009
RNA polymerase II transcription factor activity 0.698266875418824 bayes_pls_golite062009

Predicted Domain #2
Region A:
Residues: [76-232]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 RYHEGVFLIL QDLNNNGTHA ARKWKDVYGV LLGTQLALWD AKELAEFTDP SCPVSEKKLK  60
   61 EVASKPTYIN LTDATLRTLD NSDNIVMECG KNLTNALVVS TTLKNRYFLQ FGNKESFNAW 120
  121 NSAIRLCLYE CSSLQEAYTG AFISSRGAKL GDIRILL

[Run NCBI BLAST on this sequence.]

Detection Method: Pfam
Confidence: 8.585027
Match: PF00169
Description: PH domain

Shown below is our most confident prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #3
Region A:
Residues: [233-331]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 TNRKYDYKDW VSVRFGAGMP WKRCYAVISQ SSSKKKGHFG EINLYENDKK VKKNHAMATI  60
   61 VEAKALYAVY PSSPKLIDSS TIIKVVGSVK FEKKESAQE

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #4
Region A:
Residues: [332-1060]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 KDVFIMPEKH QAVPSYDTII RFLIPAMDTF KLYGRPEKLL SSKNDPHSLL FGLPVLPHIY  60
   61 YLEVEDLLPL TNSVSSLHWS NNEWKEHISD ILQRKIAQGY CGCNSTSNIT SPLPSPFLGS 120
  121 ADLFERADGV LSPKLSYGSK SSSNNSSKNS LPKRERVKLS SSSEQDLNNS DSPSIKRKSP 180
  181 PLVISESPHK VHTPTDASFR TRVTEGSPYA KQRHPKPFAS SVNDSPSDRA KSRTVPYNNN 240
  241 DRKATTPEKF ERGETSCGKN VDESLEKVRN MKLEIPESNF DKFMTDKNLL SVDSKCSNEK 300
  301 KLSVESDLSA IYEKYSNGPF GHTEGLNGSS DETYLRFQRA SVHSESNYNS RKSFTPSDFS 360
  361 NGNEEEHAVL QELNSLTQRI NELGMESINS NSDSDRINGS YSQVDFGNNN DEDDMNLFDP 420
  421 DFMAQDQLRA EERDYNKDDR TPLAKVPAAF QSTGLGITPD DDIERQYITE HRSRHEVPKR 480
  481 SPEKPSNPLE IGNPYAKPGT RLNTTHTHSK TDRSITPQRG QPVPSGQQIS SYVQPANINS 540
  541 PNKMYGANNS AMGSPRNPKT RAPPGPYNQG WNNRPSPSNI YQRPHPSDTQ PQAYHLPGNP 600
  601 YSTGNRPNMQ AQYHPQQVPM PILQQPNRPY QPYAMNTHMG SPGGYAGAAP PFQPANVNYN 660
  661 TRPQQPWPTP NSPSAHYRPP PNLNQPQNGS AGYYRPPAPQ LQNSQARPQK KDGFSQFMPS 720
  721 ATTKNPYAQ

[Run NCBI BLAST on this sequence.]

Detection Method: MSA

Shown below is our most confident prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #5
Region A:
Residues: [792-865]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 DDIERQYITE HRSRHEVPKR SPEKPSNPLE IGNPYAKPGT RLNTTHTHSK TDRSITPQRG  60
   61 QPVPSGQQIS SYVQ

[Run NCBI BLAST on this sequence.]

Detection Method: MSA

Shown below is our most confident prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #6
Region A:
Residues: [866-1060]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 PANINSPNKM YGANNSAMGS PRNPKTRAPP GPYNQGWNNR PSPSNIYQRP HPSDTQPQAY  60
   61 HLPGNPYSTG NRPNMQAQYH PQQVPMPILQ QPNRPYQPYA MNTHMGSPGG YAGAAPPFQP 120
  121 ANVNYNTRPQ QPWPTPNSPS AHYRPPPNLN QPQNGSAGYY RPPAPQLQNS QARPQKKDGF 180
  181 SQFMPSATTK NPYAQ

[Run NCBI BLAST on this sequence.]

Detection Method: MSA

Shown below is our most confident prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.


YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle