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View Structure Prediction Details

Protein: IST1
Organism: Saccharomyces cerevisiae
Length: 298 amino acids
Reference: Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for IST1.

Description E-value Query
Range
Subject
Range
gi|42569161 - gi|42569161|ref|NP_179561.2| unknown protein [Arabidopsis thaliana]
275.0 [0..10] [240..12]
gi|13279329, gi|... - gi|41281489|ref|NP_055576.2| MAPK activating protein PM28 [Homo sapiens], gi|13279329|gb|AAH04359.1|...
248.0 [0..11] [205..10]
gi|115439473, gi... - gi|115439473|ref|NP_001044016.1| Os01g0706400 [Oryza sativa (japonica cultivar-group)], gi|113533547...
247.0 [0..11] [244..36]

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Predicted Domain #1
Region A:
Residues: [1-151]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MAPSMIPFTI KLKTCLKMCI QRLRYAQEKQ QAIAKQSRRQ VAQLLLTNKE QKAHYRVETL  60
   61 IHDDIHIELL EILELYCELL LARVQVINDI STEEQLVKEH MDDGINEAIR SLIYAILFVD 120
  121 EVKELSQLKD LMAWKINVEF VNGVIADHID V

[Run NCBI BLAST on this sequence.]

Detection Method: Pfam
Confidence: 74.148742
Match: PF03398
Description: Eukaryotic protein of unknown function, DUF292

Shown below are all of our structure predictions for this domain.
Click here to view only most confident match.

Found no structure predictions for this domain.

Predicted Domain #2
Region A:
Residues: [152-232]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 PEKIIKKCSP SVPKEELVDL YLKEIAKTYD VPYSKLENSL SSSSSNISSD FSDPSGDIED  60
   61 NDEEKPILAL DNDDNDNADA K

[Run NCBI BLAST on this sequence.]

Detection Method: MSA

Shown below are all of our structure predictions for this domain.
Click here to view only most confident match.

    MCM
Score
GO
Score
GO
Term
SCOP
Match
SCOP Description
View Download 0.491 N/A N/A d.45.1 ClpS-like
View Download 0.473 N/A N/A a.76.1 Iron-dependent represor protein, dimerization domain
View Download 0.449 N/A N/A a.101.1 Uteroglobin-like
View Download 0.443 N/A N/A a.76.1 Iron-dependent represor protein, dimerization domain
View Download 0.421 N/A N/A a.4.1 Homeodomain-like
View Download 0.381 N/A N/A a.126.1 Serum albumin-like
View Download 0.381 N/A N/A a.126.1 Serum albumin-like
View Download 0.349 N/A N/A a.76.1 Iron-dependent represor protein, dimerization domain

Predicted Domain #3
Region A:
Residues: [233-298]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 HPITVKKPRQ NSENIKNELK IPKDIKKEVI EKKQSEKKTT KRKTKKEQEN DELDELKKRF  60
   61 DALRRK

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below are all of our de novo (Rosetta) predictions for this domain.
Click here to view only most confident match.

    MCM
Score
SCOP
Match
SCOP Description
View Download 0.737 a.4.1 Homeodomain-like
View Download 0.737 a.4.1 Homeodomain-like
View Download 0.694 a.239.1 Description not found.
View Download 0.632 a.24.13 Domain of the SRP/SRP receptor G-proteins
View Download 0.632 a.24.13 Domain of the SRP/SRP receptor G-proteins
View Download 0.589 a.112.1 Description not found.
View Download 0.589 a.177.1 Sigma2 domain of RNA polymerase sigma factors
View Download 0.574 a.239.1 Description not found.
View Download 0.497 a.112.1 Description not found.


YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle