| Protein: | SIP3 |
| Organism: | Saccharomyces cerevisiae |
| Length: | 1229 amino acids |
| Reference: | Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076 |
Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for SIP3.
| Description | E-value | Query Range |
Subject Range |
|
|
0.0 | [10..1224] | [5..1223] |
|
|
0.0 | [15..1221] | [14..1184] |
|
|
6.0E-99 | [15..512] | [3..480] |
|
|
2.0E-96 | [15..512] | [3..480] |
|
Region A: Residues: [1-162] |
1 11 21 31 41 51
| | | | | |
1 MSVHGRDPKK RQLRLISVAF KEASIDSPSF RASVNFFQTR VDALEDWIEK TVDFFDQKYK 60
61 VSFEDFRRAK ETLLSQLLPP PALLSNGFVS NQSFTPRLID SFNKDYYDFS MKLLQIVKGD 120
121 DSSHSTALLE LMTTAIEPYR NVRKNFDFYQ GKYDSMLASY QA
|
| Detection Method: |  |
| Confidence: | 8.39 |
| Match: | 1hciA |
| Description: | alpha-actinin |
Matching Structure (courtesy of the PDB): |
|
|
Region A: Residues: [163-295] |
1 11 21 31 41 51
| | | | | |
1 IRISKTSLEP SSIKSDALQL FEVQKNYLKA SLDLISAISA VKLSLDKFIL ESMKVLKSRS 60
61 IFITKDSGRK IDLSPCINEY LDNYAIWVEN SIEGSKVLDS DISNAKKQAY RYTLKRITPS 120
121 SDTSDYNIRS IHS
|
| Detection Method: | |
| Confidence: | 8.39 |
| Match: | 1hciA |
| Description: | alpha-actinin |
| Matching Structure (courtesy of the PDB): |
|
| Term | Confidence | Notes |
| protein binding | 2.87709153890286 | bayes_pls_golite062009 |
| binding | 2.49469149705983 | bayes_pls_golite062009 |
| transcription regulator activity | 1.84353598946956 | bayes_pls_golite062009 |
| transcription activator activity | 1.43685458873431 | bayes_pls_golite062009 |
| protein complex binding | 0.766875425740451 | bayes_pls_golite062009 |
| protein dimerization activity | 0.714083718942824 | bayes_pls_golite062009 |
| cytoskeletal protein binding | 0.702467163177926 | bayes_pls_golite062009 |
| actin filament binding | 0.519116785342072 | bayes_pls_golite062009 |
| actin binding | 0.488445831670609 | bayes_pls_golite062009 |
| identical protein binding | 0.445600866032313 | bayes_pls_golite062009 |
| receptor binding | 0.194422600694449 | bayes_pls_golite062009 |
|
Region A: Residues: [296-414] |
1 11 21 31 41 51
| | | | | |
1 SKLLSKDTQV PPKSPEKSGW LYMKTQVGKP TREIWVRRWC FLKNAVFGMF LLSPSKTYVE 60
61 ETDKFGVFLT NVRYDPEEDR KFCFEVKIFG NKVTEAHDNM SKDITLVFQT SNYLDLKSW
|
| Detection Method: | |
| Confidence: | 21.69897 |
| Match: | 1fhwA_ |
| Description: | Grp1 |
Matching Structure (courtesy of the PDB): |
|
| Term | Confidence | Notes |
| protein binding | 3.17213698546013 | bayes_pls_golite062009 |
| binding | 2.86147407357315 | bayes_pls_golite062009 |
| transcription regulator activity | 1.50756932992573 | bayes_pls_golite062009 |
| nucleic acid binding | 1.2749362891779 | bayes_pls_golite062009 |
| DNA binding | 1.18878662922624 | bayes_pls_golite062009 |
| protein domain specific binding | 0.236765394237244 | bayes_pls_golite062009 |
| RNA polymerase II transcription factor activity | 0.198922924806251 | bayes_pls_golite062009 |
|
Region A: Residues: [415-544] |
1 11 21 31 41 51
| | | | | |
1 LIAFEATKKY VMSIQHDSLE YELAFKRFSP KFFEFASSTT TSIDQLITTF DKETESLYET 60
61 LNCSISEYDI LTLGEEKVFQ FQMPTTPIST KMTQLAILSN FLTKGSWFPN AVLANIWGTT 120
121 DWSEYTILPG
|
| Detection Method: | |
| Confidence: | 16.221849 |
| Match: | 1f7cA_ |
| Description: | Graf |
Matching Structure (courtesy of the PDB): |
|
| Term | Confidence | Notes |
| nucleoside-triphosphatase regulator activity | 2.61550569370396 | bayes_pls_golite062009 |
| GTPase regulator activity | 2.61081671466585 | bayes_pls_golite062009 |
| enzyme regulator activity | 2.53838406230782 | bayes_pls_golite062009 |
| GTPase activator activity | 2.52969145422806 | bayes_pls_golite062009 |
| enzyme activator activity | 2.46273035998947 | bayes_pls_golite062009 |
| protein binding | 2.26542009538814 | bayes_pls_golite062009 |
| small GTPase regulator activity | 2.21201833406952 | bayes_pls_golite062009 |
| Ras GTPase activator activity | 2.13452947899012 | bayes_pls_golite062009 |
| Rho GTPase activator activity | 1.92471602317159 | bayes_pls_golite062009 |
| binding | 1.83836418355857 | bayes_pls_golite062009 |
| transcription regulator activity | 1.71759999912525 | bayes_pls_golite062009 |
| nucleic acid binding | 1.5568815907458 | bayes_pls_golite062009 |
| DNA binding | 1.36539411736492 | bayes_pls_golite062009 |
| Rac GTPase activator activity | 0.706062334267926 | bayes_pls_golite062009 |
|
Region A: Residues: [545-1229] |
1 11 21 31 41 51
| | | | | |
1 KGKKPSSLLT IDGKRLPIRN STIYPQYYSN ELKVLDLQFK SLVFSPDQRL EKLPEELLLF 60
61 KFEALWCPNK KQKFSATCFC TKDYIYCYMN SMEFICLTKI SLSEIVSVEA DRSSKKTLKL 120
121 YDASGLQMKA IVLFSDYKLI ASKLQYLLEN KAIKNPNSNE EILVKFEQME KESQEKKQEE 180
181 LYKIEQENSF DRKATSVSKI IKSRVTFWEM SDDASTLLNR LKKLQTEYSI TYNHEYEISS 240
241 KGLAHILFGD KSNAFPKCLF LARKDGEEHG KRFWYKNKDI NGKSQLVRKI PFRLDMTGNF 300
301 LNTGKYHRDK ESKMIFATQR IVKIVDNKYY EVDLDPFFVK VPFCHLLKLS IKFVITESYD 360
361 VDNHLEIKLN MTASSSSLHV LYKLEYIDSR TGKTIEKLSL AEIICQTWAL KFAHSEFLLI 420
421 RRVLRYYLEK IGKHGKVIKA IKLCGILGVL SNKSEEPATE KNGNSKESES MQYDIRYSCT 480
481 ILFLVFIKLM VYRVTNLTFV FFRILIGILL LCAEKFSRIN RMMVVGLLAS IMINILLSEK 540
541 ASVPYWSIKR AEKLFHDRLG SDKFTMQRAI YISDSDLLSS QLSVPSNNPI FEKFSEDNFN 600
601 KDYQYSETRK QLAMRRNELL IELRILQDME KQLVHDDYEK FLLEEVNKCS MVSIEMTDLW 660
661 FNDTQLQNYC SICNEELEKL RPPIT
|
| Detection Method: | |
Shown below are all of our de novo (Rosetta) predictions for this domain.
Click here to view only most confident match.
Found no structure predictions for this domain.
