| Protein: | FOL1 |
| Organism: | Saccharomyces cerevisiae |
| Length: | 864 amino acids |
| Reference: | Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076 |
Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for FOL1.
| Description | E-value | Query Range |
Subject Range |
|
|
0.0 | [53..861] | [30..737] |
|
|
0.0 | [60..860] | [4..683] |
|
|
0.0 | [302..861] | [52..548] |
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0.0 | [303..861] | [7..505] |
|
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0.0 | [323..861] | [1..470] |
|
|
0.0 | [335..863] | [2..448] |
|
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0.0 | [210..856] | [49..662] |
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0.0 | [210..862] | [49..672] |
|
Region A: Residues: [1-220] |
1 11 21 31 41 51
| | | | | |
1 MINCKVIENR RTRFFPLVNA KLVKVIASSL INKFQSLPLA MSKLFSTVNS ARHSVPLGGM 60
61 RDYVHIKKLE MNTVLGPDSW NQLMPQKCLL SLDMGTDFSK SAATDDLKYS LNYAVISRDL 120
121 TNFVSKKKNW GSVSNLAKSV SQFVMDKYSG VECLNLEVQA DTTHIRSDHI SCIIQQERGN 180
181 PESQEFDVVR ISELKMLTLI GVFTFERLKK QYVTLDIKLP
|
| Detection Method: |  |
| Confidence: | 34.154902 |
| Match: | 1dhn__ |
| Description: | 7,8-dihydroneopterin aldolase |
Matching Structure (courtesy of the PDB): |
|
|
Region A: Residues: [221-318] |
1 11 21 31 41 51
| | | | | |
1 WPKKAELPPP VQSIIDNVVK FVEESNFKTV EALVESVSAV IAHNEYFQKF PDSPLVVKVL 60
61 KLNAITATEG VGVSCIREPR EIAMVNIPYL SSIHESSD
|
| Detection Method: | |
Shown below are all of our de novo (Rosetta) predictions for this domain.
Click here to view only most confident match.
| MCM Score |
SCOP Match |
SCOP Description | ||
| View | Download | 0.748 | c.78.2 | Aspartate/glutamate racemase |
| View | Download | 0.568 | a.24.17 | Group V grass pollen allergen |
| View | Download | 0.652 | a.24.7 | FKBP12-rapamycin-binding domain of FKBP-rapamycin-associated protein (FRAP) |
| View | Download | 0.532 | a.17.1 | p8-MTCP1 |
| View | Download | 0.609 | a.24.7 | FKBP12-rapamycin-binding domain of FKBP-rapamycin-associated protein (FRAP) |
| View | Download | 0.510 | a.135.1 | Tetraspanin |
| View | Download | 0.497 | a.24.17 | Group V grass pollen allergen |
| View | Download | 0.482 | a.52.1 | Bifunctional inhibitor/lipid-transfer protein/seed storage 2S albumin |
| View | Download | 0.474 | a.71.2 | Helical domain of Sec23/24 |
| View | Download | 0.470 | c.78.2 | Aspartate/glutamate racemase |
| View | Download | 0.436 | a.60.6 | DNA polymerase beta, N-terminal domain-like |
| View | Download | 0.432 | a.23.1 | HSC20 (HSCB), C-terminal oligomerisation domain |
| View | Download | 0.431 | a.23.1 | HSC20 (HSCB), C-terminal oligomerisation domain |
| View | Download | 0.429 | f.36.1 | Neurotransmitter-gated ion-channel pransmembrane pore |
| View | Download | 0.427 | a.24.7 | FKBP12-rapamycin-binding domain of FKBP-rapamycin-associated protein (FRAP) |
| View | Download | 0.403 | a.60.6 | DNA polymerase beta, N-terminal domain-like |
| View | Download | 0.399 | a.27.1 | Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases |
| View | Download | 0.396 | a.24.13 | Domain of the SRP/SRP receptor G-proteins |
| View | Download | 0.389 | c.78.2 | Aspartate/glutamate racemase |
| View | Download | 0.386 | a.24.17 | Group V grass pollen allergen |
| View | Download | 0.383 | a.24.17 | Group V grass pollen allergen |
| View | Download | 0.383 | a.71.1 | Endoplasmic reticulum protein ERP29, C-domain |
| View | Download | 0.379 | a.45.1 | Glutathione S-transferase (GST), C-terminal domain |
| View | Download | 0.376 | a.60.9 | lambda integrase-like, N-terminal domain |
| View | Download | 0.376 | b.101.1 | Ribonuclease domain of colicin E3 |
| View | Download | 0.374 | a.23.1 | HSC20 (HSCB), C-terminal oligomerisation domain |
| View | Download | 0.373 | a.17.1 | p8-MTCP1 |
| View | Download | 0.369 | a.24.7 | FKBP12-rapamycin-binding domain of FKBP-rapamycin-associated protein (FRAP) |
| View | Download | 0.366 | a.24.7 | FKBP12-rapamycin-binding domain of FKBP-rapamycin-associated protein (FRAP) |
| View | Download | 0.355 | a.7.6 | Ribosomal protein S20 |
| View | Download | 0.350 | a.7.6 | Ribosomal protein S20 |
| View | Download | 0.348 | a.24.4 | Hemerythrin |
| View | Download | 0.348 | a.7.2 | Enzyme IIa from lactose specific PTS, IIa-lac |
| View | Download | 0.346 | a.23.1 | HSC20 (HSCB), C-terminal oligomerisation domain |
| View | Download | 0.344 | a.7.2 | Enzyme IIa from lactose specific PTS, IIa-lac |
| View | Download | 0.342 | b.60.1 | Lipocalins |
| View | Download | 0.339 | a.52.1 | Bifunctional inhibitor/lipid-transfer protein/seed storage 2S albumin |
| View | Download | 0.338 | a.27.1 | Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases |
| View | Download | 0.334 | a.23.1 | HSC20 (HSCB), C-terminal oligomerisation domain |
| View | Download | 0.333 | a.7.2 | Enzyme IIa from lactose specific PTS, IIa-lac |
| View | Download | 0.332 | c.78.2 | Aspartate/glutamate racemase |
| View | Download | 0.332 | a.80.1 | DNA polymerase III clamp loader subunits, C-terminal domain |
| View | Download | 0.331 | a.71.2 | Helical domain of Sec23/24 |
| View | Download | 0.329 | a.71.1 | Endoplasmic reticulum protein ERP29, C-domain |
| View | Download | 0.329 | a.181.1 | Antibiotic binding domain of TipA-like multidrug resistance regulators |
| View | Download | 0.327 | a.24.7 | FKBP12-rapamycin-binding domain of FKBP-rapamycin-associated protein (FRAP) |
| View | Download | 0.327 | c.78.2 | Aspartate/glutamate racemase |
| View | Download | 0.324 | d.110.1 | Profilin (actin-binding protein) |
| View | Download | 0.323 | a.71.2 | Helical domain of Sec23/24 |
| View | Download | 0.323 | a.71.2 | Helical domain of Sec23/24 |
| View | Download | 0.319 | a.24.10 | Histidine-containing phosphotransfer domain, HPT domain |
| View | Download | 0.319 | a.24.17 | Group V grass pollen allergen |
| View | Download | 0.318 | a.24.16 | Nucleotidyltransferase substrate binding subunit/domain |
| View | Download | 0.318 | a.118.1 | ARM repeat |
| View | Download | 0.315 | a.24.10 | Histidine-containing phosphotransfer domain, HPT domain |
| View | Download | 0.311 | a.24.7 | FKBP12-rapamycin-binding domain of FKBP-rapamycin-associated protein (FRAP) |
| View | Download | 0.311 | a.27.1 | Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases |
| View | Download | 0.310 | a.24.9 | alpha-catenin/vinculin |
| View | Download | 0.306 | a.13.1 | alpha-2-Macroglobulin receptor associated protein (RAP) domain 1 |
| View | Download | 0.305 | c.78.2 | Aspartate/glutamate racemase |
| View | Download | 0.305 | a.24.4 | Hemerythrin |
| View | Download | 0.305 | a.46.1 | Methionine synthase domain |
| View | Download | 0.300 | a.24.7 | FKBP12-rapamycin-binding domain of FKBP-rapamycin-associated protein (FRAP) |
| View | Download | 0.300 | a.135.1 | Tetraspanin |
| View | Download | 0.298 | a.27.1 | Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases |
| View | Download | 0.296 | c.78.2 | Aspartate/glutamate racemase |
| View | Download | 0.296 | a.24.11 | Bacterial GAP domain |
| View | Download | 0.295 | a.24.9 | alpha-catenin/vinculin |
| View | Download | 0.286 | f.36.1 | Neurotransmitter-gated ion-channel pransmembrane pore |
| View | Download | 0.286 | c.78.2 | Aspartate/glutamate racemase |
| View | Download | 0.286 | a.118.9 | ENTH/VHS domain |
| View | Download | 0.286 | a.24.9 | alpha-catenin/vinculin |
| View | Download | 0.283 | f.36.1 | Neurotransmitter-gated ion-channel pransmembrane pore |
| View | Download | 0.281 | a.24.4 | Hemerythrin |
| View | Download | 0.281 | a.24.9 | alpha-catenin/vinculin |
| View | Download | 0.281 | a.17.1 | p8-MTCP1 |
| View | Download | 0.281 | a.17.1 | p8-MTCP1 |
| View | Download | 0.280 | i.11.1 | Computational models partly based on NMR data |
| View | Download | 0.276 | a.24.9 | alpha-catenin/vinculin |
| View | Download | 0.275 | a.52.1 | Bifunctional inhibitor/lipid-transfer protein/seed storage 2S albumin |
| View | Download | 0.275 | a.47.2 | t-snare proteins |
| View | Download | 0.272 | d.110.4 | SNARE-like |
| View | Download | 0.271 | d.52.1 | Alpha-lytic protease prodomain |
| View | Download | 0.270 | a.21.1 | HMG-box |
| View | Download | 0.268 | d.58.17 | Metal-binding domain |
| View | Download | 0.267 | a.4.5 | "Winged helix" DNA-binding domain |
| View | Download | 0.266 | a.4.9 | Polynucleotide phosphorylase/guanosine pentaphosphate synthase (PNPase/GPSI), domain 3 |
| View | Download | 0.265 | i.11.1 | Computational models partly based on NMR data |
| View | Download | 0.264 | a.27.1 | Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases |
| View | Download | 0.260 | a.45.1 | Glutathione S-transferase (GST), C-terminal domain |
| View | Download | 0.259 | a.49.1 | C-terminal domain of B transposition protein |
| View | Download | 0.257 | a.24.13 | Domain of the SRP/SRP receptor G-proteins |
| View | Download | 0.256 | a.118.8 | TPR-like |
| View | Download | 0.255 | a.24.9 | alpha-catenin/vinculin |
| View | Download | 0.254 | a.45.1 | Glutathione S-transferase (GST), C-terminal domain |
| View | Download | 0.253 | a.24.10 | Histidine-containing phosphotransfer domain, HPT domain |
| View | Download | 0.252 | a.118.8 | TPR-like |
| View | Download | 0.247 | d.93.1 | SH2 domain |
| View | Download | 0.244 | a.59.1 | PAH2 domain |
| View | Download | 0.243 | a.27.1 | Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases |
| View | Download | 0.242 | a.52.1 | Bifunctional inhibitor/lipid-transfer protein/seed storage 2S albumin |
| View | Download | 0.241 | a.4.5 | "Winged helix" DNA-binding domain |
| View | Download | 0.239 | a.52.1 | Bifunctional inhibitor/lipid-transfer protein/seed storage 2S albumin |
| View | Download | 0.235 | a.4.9 | Polynucleotide phosphorylase/guanosine pentaphosphate synthase (PNPase/GPSI), domain 3 |
| View | Download | 0.234 | a.52.1 | Bifunctional inhibitor/lipid-transfer protein/seed storage 2S albumin |
| View | Download | 0.232 | a.24.9 | alpha-catenin/vinculin |
| View | Download | 0.231 | a.4.9 | Polynucleotide phosphorylase/guanosine pentaphosphate synthase (PNPase/GPSI), domain 3 |
| View | Download | 0.229 | a.24.9 | alpha-catenin/vinculin |
| View | Download | 0.229 | a.24.9 | alpha-catenin/vinculin |
| View | Download | 0.228 | a.24.9 | alpha-catenin/vinculin |
| View | Download | 0.228 | a.24.9 | alpha-catenin/vinculin |
| View | Download | 0.226 | a.24.10 | Histidine-containing phosphotransfer domain, HPT domain |
| View | Download | 0.224 | d.58.49 | YajQ-like |
| View | Download | 0.220 | d.15.6 | Superantigen toxins, C-terminal domain |
| View | Download | 0.217 | a.4.5 | "Winged helix" DNA-binding domain |
| View | Download | 0.216 | f.36.1 | Neurotransmitter-gated ion-channel pransmembrane pore |
| View | Download | 0.215 | f.36.1 | Neurotransmitter-gated ion-channel pransmembrane pore |
| View | Download | 0.214 | f.36.1 | Neurotransmitter-gated ion-channel pransmembrane pore |
| View | Download | 0.213 | i.11.1 | Computational models partly based on NMR data |
| View | Download | 0.212 | a.24.16 | Nucleotidyltransferase substrate binding subunit/domain |
| View | Download | 0.210 | a.24.16 | Nucleotidyltransferase substrate binding subunit/domain |
| View | Download | 0.210 | a.24.9 | alpha-catenin/vinculin |
| View | Download | 0.209 | a.25.2 | Thermoplasma ferritin-like 4-helical bundle |
| View | Download | 0.209 | a.24.4 | Hemerythrin |
| View | Download | 0.208 | a.13.1 | alpha-2-Macroglobulin receptor associated protein (RAP) domain 1 |
| View | Download | 0.208 | a.11.2 | Second domain of FERM |
| View | Download | 0.206 | a.16.1 | S15/NS1 RNA-binding domain |
| View | Download | 0.206 | a.24.9 | alpha-catenin/vinculin |
| View | Download | 0.206 | a.4.9 | Polynucleotide phosphorylase/guanosine pentaphosphate synthase (PNPase/GPSI), domain 3 |
| View | Download | 0.204 | a.66.1 | Transducin (alpha subunit), insertion domain |
| View | Download | 0.204 | a.24.4 | Hemerythrin |
| View | Download | 0.202 | a.45.1 | Glutathione S-transferase (GST), C-terminal domain |
| View | Download | 0.200 | d.131.1 | DNA clamp |
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Region A: Residues: [319-514] |
1 11 21 31 41 51
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1 IKFQLSSSQN TPIEGKNTWK RAFLAFGSNI GDRFKHIQMA LQLLSREKTV KLRNISSIFE 60
61 SEPMYFKDQT PFMNGCVEVE TLLTPSELLK LCKKIEYEEL QRVKHFDNGP RTIDLDIVMF 120
121 LNSAGEDIIV NEPDLNIPHP RMLERTFVLE PLCELISPVH LHPVTAEPIV DHLKQLYDKQ 180
181 HDEDTLWKLV PLPYRS
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| Detection Method: | |
| Confidence: | 202.751666 |
| Match: | 1dy3A_ |
| Description: | 6-hydroxymethyl-7,8-dihydropterin pyrophosphokinase, HPPK |
Matching Structure (courtesy of the PDB): |
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Region A: Residues: [515-680] |
1 11 21 31 41 51
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1 GVEPRFLKFK TATKLDEFTG ETNRITVSPT YIMAIFNATP DSFSDGGEHF ADIESQLNDI 60
61 IKLCKDALYL HESVIIDVGG CSTRPNSIQA SEEEEIRRSI PLIKAIREST ELPQDKVILS 120
121 IDTYRSNVAK EAIKVGVDII NDISGGLFDS NMFAVIAENP EICYIL
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Region B: Residues: [740-752] |
1 11 21 31 41 51
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1 IKAIDNGVKR WQI
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| Detection Method: | |
| Confidence: | 361.594777 |
| Match: | 1aj0__ |
| Description: | Dihydropteroate synthetase |
Matching Structure (courtesy of the PDB): |
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Region A: Residues: [681-739] |
1 11 21 31 41 51
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1 SHTRGDISTM NRLAHYENFA LGDSIQQEFV HNTDIQQLDD LKDKTVLIRN VGQEIGERY
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Region B: Residues: [753-864] |
1 11 21 31 41 51
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1 LIDPGLGFAK TWKQNLQIIR HIPILKNYSF TMNSNNSQVY VNLRNMPVLL GPSRKKFIGH 60
61 ITKDVDAKQR DFATGAVVAS CIGFGSDMVR VHDVKNCSKS IKLADAIYKG LE
|
| Detection Method: | |
| Confidence: | 361.594777 |
| Match: | 1aj0__ |
| Description: | Dihydropteroate synthetase |
| Matching Structure (courtesy of the PDB): |
|
