YRC Public Data Repository - Protein Structure Prediction

Protein:	YNL217W
Organism:	Saccharomyces cerevisiae
Length:	326 amino acids
Reference:	Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for YNL217W.

Description	E-value	Query Range	Subject Range
PP11_ACEPE - Serine/threonine-protein phosphatase PP1 isozyme 1 OS=Acetabularia peniculus PE=3 SV=1	3.0E-79	[14..272]	[7..258]
gi\|5053113, gi\|1... - gi\|5053113\|gb\|AAD38856.1\| phosphatase PP1 [Chlamydomonas reinhardtii], gi\|159487112\|ref\|XP_001701579...	8.0E-79	[14..255]	[7..241]
gi\|7507776 - gi\|7507776\|pir\|\|T16867 probable cytochrome P450 T13C5.1 [similarity] - Caenorhabditis elegans	3.0E-78	[7..265]	[1..252]
PP11_ARATH - Serine/threonine-protein phosphatase PP1 isozyme 1 OS=Arabidopsis thaliana GN=TOPP1 PE=2 SV=1	6.0E-78	[2..265]	[10..268]
gi\|999339 - gi\|999339\|gb\|AAB34333.1\| protein phosphatase 1 alpha; PP1 alpha [Rattus sp.] PP1A_RABIT - Serine/threonine-protein phosphatase PP1-alpha catalytic subunit OS=Oryctolagus cuniculus GN=PPP1CA ... PPP1CA - protein phosphatase 1, catalytic subunit, alpha isozyme ENSMMUG000000172... - null, null PP1A_BOVIN - Serine/threonine-protein phosphatase PP1-alpha catalytic subunit OS=Bos taurus GN=PPP1CA PE=2 SV=1 IPI:IPI00323370.... - Ensembl_locations(Chr-bp):None Serine/threonine protein phosphatase PP1-alpha 1 catalytic subunit PP1A_RAT - Serine/threonine-protein phosphatase PP1-alpha catalytic subunit OS=Rattus norvegicus GN=Ppp1ca PE=1... gi\|60656413 - gi\|60656413\|gb\|AAX32770.1\| protein phosphatase 1 catalytic subunit alpha isoform [synthetic construc... HGNC:9281\|MIM:17... - phosphatase 1, catalytic subunit, alpha isozyme gi\|87621715, gi\|... - gi\|87621715\|gb\|ABD38708.1\| protein phosphatase 1 catalytic subunit alpha isoform [Sus scrofa], gi\|11...	8.0E-78	[14..265]	[10..256]
gi\|1535 - gi\|1535\|emb\|CAA30645.1\| unnamed protein product [Oryctolagus cuniculus]	8.0E-78	[14..265]	[10..256]
PP1_EMENI - Serine/threonine-protein phosphatase PP1 OS=Emericella nidulans GN=bimG PE=2 SV=1 PP1_EMENI - Serine/threonine-protein phosphatase PP1 OS=Emericella nidulans (strain FGSC A4 / ATCC 38163 / CBS 1...	9.0E-78	[14..265]	[9..255]
PP1A_MOUSE - Serine/threonine-protein phosphatase PP1-alpha catalytic subunit OS=Mus musculus GN=Ppp1ca PE=1 SV=1 tr\|G3MX90\|G3MX90... - Serine/threonine-protein phosphatase OS=Bos taurus PE=3 SV=1 gi\|54035381 - gb\|AAH84049.1\| Unknown (protein for MGC:98412) [Xenopus laevis]	9.0E-78	[14..265]	[10..256]

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Predicted Domain #1

Region A:
Residues: [1-326]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MEDKRKRRAA TLSTALILFV ACCVYTLYIF KFDNPRLSPP VSLLPTISTL KKIEHVTDLN  60
   61 KEYVFVGDVH GNYDEFIELI DDKIGGLGEN ITMILLGDFI HKGPDSDKVV SYILNHKDQV 120
  121 KCVLGNHEIL VMMAYLNPDF SKWVRRPKLM TPLTFSTETN FIPQDISKIS NAHGRLAREL 180
  181 GFSKLSQLAE HCSMAIELDL DITGDILFGA HAGMVPGDFM KPNQIPGVSS LSNMKYVDKK 240
  241 NWSKTSREKE NKNYVRWYTL WDKYGDHFSN AKVFYGHDAS MGLNLRRQTK GLDTACIKNN 300
  301 LLSSMKVKYD IKKGQYDYEL IQVQCS

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	89.626727
Match:	1auiA_
Description:	Protein phosphatase-2B (PP-2B, calcineurin A subunit)
Matching Structure (courtesy of the PDB):

Predicted functions:

Term	Confidence	Notes
phosphoprotein phosphatase activity	2.71668087029212	bayes_pls_golite062009
hydrolase activity	2.70035826391672	bayes_pls_golite062009
protein serine/threonine phosphatase activity	2.60260030561864	bayes_pls_golite062009
phosphatase activity	2.37908688123878	bayes_pls_golite062009
phosphoric ester hydrolase activity	2.35252321251549	bayes_pls_golite062009
hydrolase activity, acting on ester bonds	1.79217430741633	bayes_pls_golite062009
catalytic activity	1.39852585255405	bayes_pls_golite062009
binding	0.423212519919938	bayes_pls_golite062009
protein binding	0.267726984138904	bayes_pls_golite062009

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits

Predicted functions: