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View Structure Prediction Details

Protein: UBP10
Organism: Saccharomyces cerevisiae
Length: 792 amino acids
Reference: Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for UBP10.

Description E-value Query
Range
Subject
Range
UBP10 - Ubiquitin-specific protease that deubiquitinates ubiquitin-protein moieties; may regulate silencing ...
0.0 [1..770] [1..770]
gi|34874937, gi|... - gi|74218334|dbj|BAE23782.1| unnamed protein product [Mus musculus], gi|34874937|gb|AAQ83304.1| deubi...
4.0E-83 [165..739] [88..619]
gi|6492126, gi|5... - gi|6492126|gb|AAF14190.1|AF106659_1 deubiquitinating enzyme Ubp69 [Rattus norvegicus], gi|51592088|r...
8.0E-83 [166..739] [89..618]
gi|20140914, gi|... - gi|5689463|dbj|BAA83015.1| KIAA1063 protein [Homo sapiens], sp|Q9UPT9|UB22_HUMAN Ubiquitin carboxyl-...
1.0E-81 [330..733] [212..588]
gi|7507776 - gi|7507776|pir||T16867 probable cytochrome P450 T13C5.1 [similarity] - Caenorhabditis elegans
4.0E-74 [6..785] [311..1107]

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Predicted Domain #1
Region A:
Residues: [1-260]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MTTQESIKPL VDRILSNPLQ FNAAMISNKS NNNDTSAAPE NSSYIVIGKQ HNNNSNSTAI  60
   61 AATAESKQIK ENNLIDRPNG KKTNTVPKSM AEALLLYTSK NDKDAADATG AKKSAELSTE 120
  121 LSTEPPSSSS EDDKVGKEEE EEGEIFHEAR DYVEPRKASL KERDNADKGD GEDIGEDIGE 180
  181 DIGEDIGEDI GEDIGENLGS PLATIDDSSN ENEKEKRKEL STSISSDDEI EDDEDEDDMD 240
  241 YDSSAMEKEL PEEEENDSSS 

[Run NCBI BLAST on this sequence.]

Detection Method: ORFEUS
Confidence: 14.16
Match: 1ldvA
Description: No description for 1ldvA was found.

Predicted Domain #2
Region A:
Residues: [261-323]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 KISEGEKKSL YQDLMENSTV EVNRYEPVNN TKENGNRNPK GEEEEEEEED LKHKSRSITP  60
   61 PVT

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below are all of our de novo (Rosetta) predictions for this domain.
Click here to view only most confident match.

    MCM
Score
SCOP
Match
SCOP Description
View Download 0.656 a.4.5 "Winged helix" DNA-binding domain
View Download 0.436 a.24.13 Domain of the SRP/SRP receptor G-proteins
View Download 0.441 a.5.6 Hypothetical protein MTH1615
View Download 0.684 a.44.1 Disulphide-bond formation facilitator (DSBA), insertion domain
View Download 0.375 a.17.1 p8-MTCP1
View Download 0.368 a.35.1 lambda repressor-like DNA-binding domains
View Download 0.347 a.46.2 Nucleoside phosphorylase/phosphoribosyltransferase N-terminal domain
View Download 0.336 a.35.1 lambda repressor-like DNA-binding domains
View Download 0.312 a.144.1 PABC (PABP) domain
View Download 0.311 a.3.1 Cytochrome c
View Download 0.306 a.74.1 Cyclin-like
View Download 0.291 a.5.1 DNA helicase RuvA subunit, C-terminal domain
View Download 0.288 a.112.1 Description not found.
View Download 0.241 a.46.2 Nucleoside phosphorylase/phosphoribosyltransferase N-terminal domain
View Download 0.239 a.49.1 C-terminal domain of B transposition protein
View Download 0.212 a.140.4 Recombination endonuclease VII, C-terminal and dimerization domains
View Download 0.209 a.35.1 lambda repressor-like DNA-binding domains
View Download 0.204 a.5.7 4-hydroxy-2-oxovalerate aldolase DmpG, communication domain
View Download 0.202 a.3.1 Cytochrome c

Predicted Domain #3
Region A:
Residues: [324-426]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 ISNLSNFYQF NENINDRGSL NSTRIVKNWG DKFTNLKPRG LLNHGVTCYT NAAVQAMLHI  60
   61 PSIQHYLFDI LMGKYDSTIS KNSVSYTLAE TSKKMWLPVS KNP

[Run NCBI BLAST on this sequence.]

Detection Method: Pfam
Confidence: 11.136677
Match: PF00442
Description: No description for PF00442 was found.

Shown below are all of our structure predictions for this domain.
Click here to view only most confident match.

Found no structure predictions for this domain.

Predicted Domain #4
Region A:
Residues: [427-560]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 RKNVSASYIN PKHLISRLDD INCMMSEWQQ EDSHEYFMSL MSRLQEDSVP KGHKLIESII  60
   61 YDIFGGLLKQ IVTCKSCGSI SKTEQPFYDL SLHLKGKKKL DPNSDLSSDS INGTSATTST 120
  121 TTSNAATKPS LSSS

[Run NCBI BLAST on this sequence.]

Detection Method: MSA

Shown below are all of our structure predictions for this domain.
Click here to view only most confident match.

    MCM
Score
GO
Score
GO
Term
SCOP
Match
SCOP Description
View Download 0.416 0.322 protein deubiquitination a.45.1 Glutathione S-transferase (GST), C-terminal domain
View Download 0.300 0.090 protein deubiquitination d.122.1 ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase
View Download 0.367 0.012 protein deubiquitination a.24.17 Group V grass pollen allergen
View Download 0.363 N/A N/A d.202.1 Transcription factor NusA, N-terminal domain
View Download 0.356 N/A N/A d.134.1 Sulfite reductase hemoprotein (SiRHP), domains 2 and 4
View Download 0.299 N/A N/A a.22.1 Histone-fold
View Download 0.284 N/A N/A d.79.1 YjgF-like
View Download 0.273 N/A N/A d.108.1 Acyl-CoA N-acyltransferases (Nat)
View Download 0.239 N/A N/A d.112.1 Phoshotransferase/anion transport protein
View Download 0.225 N/A N/A d.93.1 SH2 domain
View Download 0.207 N/A N/A c.95.1 Thiolase-like

Predicted Domain #5
Region A:
Residues: [561-649]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 SSVNLNNGSP FAAASDLSSA NRRFSIEKSI KDFFNPELIK VDKEQKGYVC EKCHKTTNAV  60
   61 KHSSILRAPE TLLVHLKKFR FNGTSSSKM

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below are all of our de novo (Rosetta) predictions for this domain.
Click here to view only most confident match.

    MCM
Score
SCOP
Match
SCOP Description
View Download 0.307 b.1.1 Immunoglobulin
View Download 0.277 a.3.1 Cytochrome c
View Download 0.366 a.24.7 FKBP12-rapamycin-binding domain of FKBP-rapamycin-associated protein (FRAP)
View Download 0.309 b.1.12 Purple acid phosphatase, N-terminal domain
View Download 0.241 b.2.5 p53-like transcription factors
View Download 0.241 a.144.1 PABC (PABP) domain
View Download 0.239 d.17.4 NTF2-like

Predicted Domain #6
Region A:
Residues: [650-792]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 KQAVSYPMFL DLTEYCESKE LPVKYQLLSV VVHEGRSLSS GHYIAHCKQP DGSWATYDDE  60
   61 YINIISERDV LKEPNAYYLL YTRLTPKSVP LPLAKSAMAT GNVTSKSKQE QAVNEPNNRP 120
  121 LKINSKKNNR KKWKKNKKRK FTK

[Run NCBI BLAST on this sequence.]

Detection Method: Pfam
Confidence: 25.522879
Match: PF00443
Description: Ubiquitin carboxyl-terminal hydrolase

Shown below are all of our structure predictions for this domain.
Click here to view only most confident match.

Found no structure predictions for this domain.


YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle