| Protein: | APC1 |
| Organism: | Saccharomyces cerevisiae |
| Length: | 1748 amino acids |
| Reference: | Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076 |
Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for APC1.
| Description | E-value | Query Range |
Subject Range |
|
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0.0 | [1..1748] | [1..1748] |
|
|
0.0 | [600..1419] | [734..1548] |
|
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0.0 | [600..1419] | [734..1548] |
|
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0.0 | [593..1419] | [434..1183] |
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0.0 | [593..1419] | [434..1183] |
|
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0.0 | [606..1421] | [939..1719] |
|
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0.0 | [619..1421] | [817..1625] |
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0.0 | [631..1416] | [586..1345] |
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0.0 | [895..1423] | [587..1180] |
|
Region A: Residues: [1-591] |
1 11 21 31 41 51
| | | | | |
1 MTSKPSTRND YLPRETHNGE YTGDSPEWQL QINITNKIGG INGDIWLSRD GRSVKWCIED 60
61 QCLRQFTYNQ KIIKAGYIDF EKTPDCFVVV LSDIAHVYML KNGGSTTVCF PFQIGNAFWY 120
121 ANGVILERET SASFMDGGYD LKPIEFDLKH KYITLTDPMA PFGLISITNT FKGGINSASG 180
181 NKTDILQDFQ LVLFPSDKDK CIAVFLDRNS KVLRFYYSRI LSSDQSRKGE LTISSTKKTG 240
241 LDAAGNSQKS GGISKDLRKF SHLTRRSTSI NSNSHDFNAA ERVLSGNVGN ASGRTDIFAL 300
301 PSSCSRRSLS ATLDRMGNNI APTNRAAPSG FFDSSSANTA THSNITPVSQ PMQQQQQEYL 360
361 NQTATSSKDI VLTEISSLKL PDDIIFTSRR LSSILSKLKF LSLRFERREG LLIFHEPTHF 420
421 CKIWLIDLLP DVLDSIPFKI YGNSPQNMIR LENLKLKEPS RIQAMYIHEL LESCLILVSE 480
481 GQNKEEYKAC LYDPFVKITS PSKNISEELT KQNSLPSLQK LFPYPETSFT KLCFEAVKYI 540
541 TSPAFNISFI FLWQSAYSIL LSRANDDVVG GLKMEHDAFS LVLSLLILPI P
|
| Detection Method: |  |
Shown below are all of our de novo (Rosetta) predictions for this domain.
Click here to view only most confident match.
Found no structure predictions for this domain.
|
Region A: Residues: [592-1445] |
1 11 21 31 41 51
| | | | | |
1 SSSAQEYQEY KEIYERDLFQ HLKQDSEITS SVLPRIVIGL HLIREEYSLN VLCRNEHALL 60
61 GQFLRFATAA MGWPDLWQSY YVPKMDSESK TFLHPREQNS TFFHPLDEPP SITKSLYSIT 120
121 ENSSIPLCPF ISFSRLVATD TQVELRITPR SFKILGLYEL VHSPNFLPDY VLGILSSFKV 180
181 DKDELQTYPL GILVPLQNIL KILEDKLSEV RDNLELLDRA DLQRCSAIIN SIRSDSKEVL 240
241 KRGQRDSYML CKVPLAKNRS SLSKKPSDIY SILSEIVKSA SQVPLDGSAM RMSNIQDDED 300
301 IDEGRSLKLN AGLIFSEDKR FTHVVSLLAY YRPTKTQFFT TKTEYAQILA QKKYFAKIMA 360
361 LRTCTNGVGW GAVAYATEKP ISTQKWVIQP LNLISVFPDD TKITVKAPED IAHDIVEWGQ 420
421 FHAGVSSGLR ISKKATGITG SWIAFNKPKE LDAYHGGFLL GLGLNGHLKN LEEWHIYNYL 480
481 SPRNTHISIG LLLGMSSSMK GSMDSKLIKV ISVHLVAFLP SGSSDLNIDL KLQTAGIIGM 540
541 GMLYLNSRHK RMSDSIFAQL VSLLNVNDEM VADEEYRLAA GISLGLINLG AGQTKLRKWD 600
601 SSLLGLGDDL PEDVYDSSDV EQNVMYEDLT TKLLEIVTST YDVENDWIPE NSQIGAVIAI 660
661 MFLFLKSNNF GISNMLKVDL KEILKANINT RPELLMYREW ASNMILWEFI GDDLSFIMKD 720
721 VDIGVKFSEL NTDLLPIYYT MAGRILAMGI RFASTGNLKI RNILLSLVDK FLPLYQYPGK 780
781 QNLDFRLTIS VINVLTNVIV VSLSMVMCAS GDLEVLRRVK YLHEVASGPY SDLFQEIPSS 840
841 KSDVSGVTQV TSNT
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| Detection Method: | |
Shown below are all of our structure predictions for this domain.
Click here to view only most confident match.
Found no structure predictions for this domain.
|
Region A: Residues: [1446-1562] |
1 11 21 31 41 51
| | | | | |
1 NTPGNSDRER VDETAASLDD ERSSNGSDIS DPTAYLEDKK DIDDHYGKFI STNLALGFLF 60
61 LGSGQYALNT STLESIAFLS MSVLPTYTTP HPLQELKHFW SIAVEPRCLV IKDISTG
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| Detection Method: | |
Shown below are all of our de novo (Rosetta) predictions for this domain.
Click here to view only most confident match.
| MCM Score |
SCOP Match |
SCOP Description | ||
| View | Download | 0.334 | a.45.1 | Glutathione S-transferase (GST), C-terminal domain |
| View | Download | 0.275 | a.7.7 | BAG domain |
| View | Download | 0.348 | c.78.2 | Aspartate/glutamate racemase |
| View | Download | 0.281 | a.24.10 | Histidine-containing phosphotransfer domain, HPT domain |
| View | Download | 0.283 | d.87.1 | FAD/NAD-linked reductases, dimerisation (C-terminal) domain |
| View | Download | 0.270 | d.52.3 | Prokaryotic type KH domain (KH-domain type II) |
| View | Download | 0.254 | c.47.1 | Thioredoxin-like |
| View | Download | 0.246 | d.14.1 | Ribosomal protein S5 domain 2-like |
| View | Download | 0.235 | a.85.1 | Hemocyanin, N-terminal domain |
| View | Download | 0.233 | a.60.9 | lambda integrase-like, N-terminal domain |
| View | Download | 0.233 | a.4.12 | TrpR-like |
| View | Download | 0.216 | d.74.3 | RBP11-like subunits of RNA polymerase |
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Region A: Residues: [1563-1645] |
1 11 21 31 41 51
| | | | | |
1 DAVNNVPIEL VVEEDVEKEE VIREISTPCL LPDFSKIKSI RVKMHGYFPL EVNFTKDYSA 60
61 SDFFSGGTII YIQRKSESVF ENK
|
| Detection Method: | |
Shown below are all of our structure predictions for this domain.
Click here to view only most confident match.
| MCM Score |
GO Score |
GO Term |
SCOP Match |
SCOP Description | ||
| View | Download | 0.537 | 0.123 | mitotic spindle elongation | b.43.4 | Riboflavin synthase domain-like |
| View | Download | 0.589 | 0.092 | mitotic spindle elongation | d.58.17 | Metal-binding domain |
| View | Download | 0.581 | 0.012 | mitotic spindle elongation | d.64.1 | eIF1-like |
| View | Download | 0.536 | 0.006 | mitotic spindle elongation | d.58.25 | Killer toxin KP6 alpha-subunit |
| View | Download | 0.529 | 0.006 | mitotic spindle elongation | d.95.1 | Glucose permease domain IIB |
| View | Download | 0.491 | N/A | N/A | b.1.2 | Fibronectin type III |
| View | Download | 0.484 | N/A | N/A | d.58.38 | Urease metallochaperone UreE, C-terminal domain |
| View | Download | 0.483 | N/A | N/A | d.58.4 | Dimeric alpha+beta barrel |
| View | Download | 0.477 | N/A | N/A | d.15.1 | Ubiquitin-like |
| View | Download | 0.464 | N/A | N/A | b.40.4 | Nucleic acid-binding proteins |
| View | Download | 0.457 | N/A | N/A | d.58.3 | Protease propeptides/inhibitors |
| View | Download | 0.439 | N/A | N/A | d.205.1 | GTP cyclohydrolase I feedback regulatory protein, GFRP |
| View | Download | 0.416 | N/A | N/A | d.58.11 | EF-G/eEF-2 domains III and V |
| View | Download | 0.377 | N/A | N/A | d.58.7 | RNA-binding domain, RBD |
| View | Download | 0.346 | N/A | N/A | b.36.1 | PDZ domain-like |
| View | Download | 0.338 | N/A | N/A | b.43.4 | Riboflavin synthase domain-like |
| View | Download | 0.335 | N/A | N/A | d.75.1 | tRNA splicing endonuclease EdnA, N-terminal domain |
| View | Download | 0.331 | N/A | N/A | b.1.2 | Fibronectin type III |
| View | Download | 0.328 | N/A | N/A | b.43.4 | Riboflavin synthase domain-like |
| View | Download | 0.307 | N/A | N/A | b.52.2 | ADC-like |
| View | Download | 0.299 | N/A | N/A | a.28.1 | ACP-like |
| View | Download | 0.296 | N/A | N/A | b.1.2 | Fibronectin type III |
| View | Download | 0.295 | N/A | N/A | d.201.1 | SRP19 |
| View | Download | 0.292 | N/A | N/A | d.199.1 | DNA-binding C-terminal domain of the transcription factor MotA |
| View | Download | 0.278 | N/A | N/A | b.1.18 | E set domains |
| View | Download | 0.271 | N/A | N/A | d.50.1 | dsRNA-binding domain-like |
| View | Download | 0.258 | N/A | N/A | a.6.1 | Putative DNA-binding domain |
| View | Download | 0.256 | N/A | N/A | b.1.2 | Fibronectin type III |
| View | Download | 0.255 | N/A | N/A | d.58.40 | D-ribose-5-phosphate isomerase (RpiA), lid domain |
| View | Download | 0.244 | N/A | N/A | b.1.18 | E set domains |
| View | Download | 0.237 | N/A | N/A | b.40.6 | MOP-like |
| View | Download | 0.236 | N/A | N/A | b.107.1 | Urease metallochaperone UreE, N-terminal domain |
| View | Download | 0.218 | N/A | N/A | b.107.1 | Urease metallochaperone UreE, N-terminal domain |
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Region A: Residues: [1646-1748] |
1 11 21 31 41 51
| | | | | |
1 ASFRNVEDIH VALKRKAAES KNYSRLNLKN EQGNTTSSQL VESLGIQDLT MVELDTLLSA 60
61 GNNTALTDSE SYNLGLLCSD KNSGDILDCQ LELWYKSFGP HDE
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| Detection Method: | |
Shown below are all of our de novo (Rosetta) predictions for this domain.
Click here to view only most confident match.
| MCM Score |
SCOP Match |
SCOP Description | ||
| View | Download | 0.669 | d.110.3 | PYP-like sensor domain (PAS domain) |
| View | Download | 0.431 | d.131.1 | DNA clamp |
| View | Download | 0.437 | d.17.1 | Cystatin/monellin |
| View | Download | 0.470 | d.200.1 | Integrin beta tail domain |
| View | Download | 0.411 | a.74.1 | Cyclin-like |
| View | Download | 0.410 | d.66.1 | Alpha-L RNA-binding motif |
| View | Download | 0.392 | c.23.1 | CheY-like |
| View | Download | 0.389 | b.1.2 | Fibronectin type III |
| View | Download | 0.387 | c.51.2 | TolB, N-terminal domain |
| View | Download | 0.373 | a.23.4 | Mitochondrial import receptor subunit Tom20 |
| View | Download | 0.360 | d.17.1 | Cystatin/monellin |
| View | Download | 0.359 | a.156.1 | S13-like H2TH domain |
| View | Download | 0.356 | b.61.4 | Quinohemoprotein amine dehydrogenase A chain, domain 3 |
| View | Download | 0.356 | d.110.1 | Profilin (actin-binding protein) |
| View | Download | 0.355 | a.24.13 | Domain of the SRP/SRP receptor G-proteins |
| View | Download | 0.344 | a.4.5 | "Winged helix" DNA-binding domain |
| View | Download | 0.340 | a.39.1 | EF-hand |
| View | Download | 0.336 | a.39.1 | EF-hand |
| View | Download | 0.335 | a.77.1 | DEATH domain |
| View | Download | 0.324 | b.128.1 | Hypothetical protein YojF |
| View | Download | 0.316 | a.4.5 | "Winged helix" DNA-binding domain |
| View | Download | 0.310 | a.39.1 | EF-hand |
| View | Download | 0.307 | d.105.1 | Clathrin adaptor appendage, alpha and beta chain-specific domain |
| View | Download | 0.304 | c.51.3 | B12-dependend dehydatases associated subunit |
| View | Download | 0.299 | c.47.1 | Thioredoxin-like |
| View | Download | 0.296 | b.106.1 | Phage tail proteins |
| View | Download | 0.291 | c.121.1 | Ribose/Galactose isomerase RpiB/AlsB |
| View | Download | 0.286 | c.48.1 | TK C-terminal domain-like |
| View | Download | 0.285 | a.39.1 | EF-hand |
| View | Download | 0.276 | d.1.1 | Microbial ribonucleases |
| View | Download | 0.274 | b.1.2 | Fibronectin type III |
| View | Download | 0.272 | a.177.1 | Sigma2 domain of RNA polymerase sigma factors |
| View | Download | 0.269 | a.4.5 | "Winged helix" DNA-binding domain |
| View | Download | 0.262 | d.228.1 | Replication modulator SeqA, C-terminal DNA-binding domain |
| View | Download | 0.253 | d.121.1 | DNA topoisomerase I domain |
| View | Download | 0.252 | a.4.1 | Homeodomain-like |
| View | Download | 0.240 | c.53.1 | Resolvase-like |
| View | Download | 0.230 | d.131.1 | DNA clamp |
| View | Download | 0.224 | d.17.5 | Uracil-DNA glycosylase inhibitor protein |
| View | Download | 0.222 | d.58.26 | GHMP Kinase, C-terminal domain |
| View | Download | 0.221 | a.4.6 | C-terminal effector domain of the bipartite response regulators |
| View | Download | 0.216 | a.24.13 | Domain of the SRP/SRP receptor G-proteins |
| View | Download | 0.216 | a.85.1 | Hemocyanin, N-terminal domain |
| View | Download | 0.213 | f.36.1 | Neurotransmitter-gated ion-channel pransmembrane pore |
| View | Download | 0.207 | d.110.3 | PYP-like sensor domain (PAS domain) |
| View | Download | 0.206 | d.110.2 | GAF domain-like |
| View | Download | 0.205 | c.16.1 | Lumazine synthase |
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Region A: Residues: [885-970] |
1 11 21 31 41 51
| | | | | |
1 NIQDDEDIDE GRSLKLNAGL IFSEDKRFTH VVSLLAYYRP TKTQFFTTKT EYAQILAQKK 60
61 YFAKIMALRT CTNGVGWGAV AYATEK
|
| Detection Method: | |
Shown below are all of our de novo (Rosetta) predictions for this domain.
Click here to view only most confident match.
Found no structure predictions for this domain.
|
Region A: Residues: [971-1025] |
1 11 21 31 41 51
| | | | | |
1 PISTQKWVIQ PLNLISVFPD DTKITVKAPE DIAHDIVEWG QFHAGVSSGL RISKK
|
| Detection Method: | |
Shown below are all of our structure predictions for this domain.
Click here to view only most confident match.
Found no structure predictions for this domain.
|
Region A: Residues: [1026-1748] |
1 11 21 31 41 51
| | | | | |
1 ATGITGSWIA FNKPKELDAY HGGFLLGLGL NGHLKNLEEW HIYNYLSPRN THISIGLLLG 60
61 MSSSMKGSMD SKLIKVISVH LVAFLPSGSS DLNIDLKLQT AGIIGMGMLY LNSRHKRMSD 120
121 SIFAQLVSLL NVNDEMVADE EYRLAAGISL GLINLGAGQT KLRKWDSSLL GLGDDLPEDV 180
181 YDSSDVEQNV MYEDLTTKLL EIVTSTYDVE NDWIPENSQI GAVIAIMFLF LKSNNFGISN 240
241 MLKVDLKEIL KANINTRPEL LMYREWASNM ILWEFIGDDL SFIMKDVDIG VKFSELNTDL 300
301 LPIYYTMAGR ILAMGIRFAS TGNLKIRNIL LSLVDKFLPL YQYPGKQNLD FRLTISVINV 360
361 LTNVIVVSLS MVMCASGDLE VLRRVKYLHE VASGPYSDLF QEIPSSKSDV SGVTQVTSNT 420
421 NTPGNSDRER VDETAASLDD ERSSNGSDIS DPTAYLEDKK DIDDHYGKFI STNLALGFLF 480
481 LGSGQYALNT STLESIAFLS MSVLPTYTTP HPLQELKHFW SIAVEPRCLV IKDISTGDAV 540
541 NNVPIELVVE EDVEKEEVIR EISTPCLLPD FSKIKSIRVK MHGYFPLEVN FTKDYSASDF 600
601 FSGGTIIYIQ RKSESVFENK ASFRNVEDIH VALKRKAAES KNYSRLNLKN EQGNTTSSQL 660
661 VESLGIQDLT MVELDTLLSA GNNTALTDSE SYNLGLLCSD KNSGDILDCQ LELWYKSFGP 720
721 HDE
|
| Detection Method: | |
| Confidence: | 0.951 |
| Match: | 2ie3A |
| Description: | No description for 2ie3A was found. |
| Term | Confidence | Notes |
| binding | 2.81296846555705 | bayes_pls_golite062009 |
| protein binding | 1.81870125631028 | bayes_pls_golite062009 |
| nucleic acid binding | 1.08079130332447 | bayes_pls_golite062009 |
| cytoskeletal protein binding | 0.73539719922204 | bayes_pls_golite062009 |
| hydrolase activity | 0.46329207154863 | bayes_pls_golite062009 |
| protein kinase activity | 0.317596068919701 | bayes_pls_golite062009 |
| DNA binding | 0.180353635969032 | bayes_pls_golite062009 |
| transferase activity, transferring phosphorus-containing groups | 0.0926408709390653 | bayes_pls_golite062009 |
| transcription regulator activity | 0.0196841005896076 | bayes_pls_golite062009 |
| actin binding | 0.00917667862812865 | bayes_pls_golite062009 |
