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View Structure Prediction Details

Protein: NST1
Organism: Saccharomyces cerevisiae
Length: 1240 amino acids
Reference: Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for NST1.

Description E-value Query
Range
Subject
Range
NST1 - Protein of unknown function, mediates sensitivity to salt stress; interacts physically with the spli...
NST1_YEAST - Stress response protein NST1 OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=NST1 PE=1 S...
0.0 [1..1240] [1..1240]
MYH4_PIG - Myosin-4 OS=Sus scrofa GN=MYH4 PE=2 SV=1
9.0E-90 [136..995] [843..1656]
MYSS_CYPCA - Myosin heavy chain, fast skeletal muscle OS=Cyprinus carpio PE=2 SV=2
5.0E-89 [136..995] [842..1655]
MYH2_BOVIN - Myosin-2 OS=Bos taurus GN=MYH2 PE=2 SV=1
1.0E-88 [136..995] [846..1659]
gi|7507776 - gi|7507776|pir||T16867 probable cytochrome P450 T13C5.1 [similarity] - Caenorhabditis elegans
2.0E-88 [136..995] [57..870]
gi|9800488, gi|1... - gi|9800488|gb|AAF99315.1|AF272034_1 fast myosin heavy chain isoform 3 [Gallus gallus], gi|165973976|...
8.0E-88 [136..995] [846..1659]

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Predicted Domain #1
Region A:
Residues: [1-135]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MPPNSKSKRR KNKSKQHNKK NGNSDPEQSI NPTQLVPRME PELYHTESDY PTSRVIKRAP  60
   61 NGDVIVEPIN TDDDKKERTA NLTHNKDSMD SASSLAFTLD SHWESLSPEE KKTILRIEKE 120
  121 EVFNVIRNYQ DDHSC

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 9.221849
Match: 1c1gA_
Description: Tropomyosin
Matching Structure (courtesy of the PDB):

Predicted Domain #2
Region A:
Residues: [136-496]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 SCSVCGRRHL AMDQEMERIY NTLYAMDKDK DPETNPIKFH LGIIKELQIS KNQQQNDLSS  60
   61 TKGEVVKNFL SSSTVGSLKE EVLHFKQKQL SKQEQAHNET ADNTSLLEEN LNNIHINKTS 120
  121 SEISANFNSV SDEELQQKYS NFTKTFISSH PKIAEEYVQK MMMYPNIRAL TDDLMNSNGQ 180
  181 GFLNAIEDFV RDGQIQASKK DDSITEDEAS STDLTDPKEF TTMLHSGKPL TEDEYADLQR 240
  241 NIAERMTNAY DTASKKFKDV SQLEKELFTR FMSGRDKKSF RELIIQSFKN KFDGELGPSV 300
  301 LAATLSSCFS SQSKDTSLDT DSIYEDEDEE DYDDYSEYAE DSEEVSEYEG IEAVEKPEHD 360
  361 E

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 54.38764
Match: 1i84S_
Description: Heavy meromyosin subfragment
Matching Structure (courtesy of the PDB):

Predicted Domain #3
Region A:
Residues: [497-776]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 KSNGIRETLH LSYDHDHKRQ NHPHHHYHST STHSEDELSE EEYISDIELP HDPHKHFHRD  60
   61 DDILDGDEDE PEEEDENEGD DEEDTYDSGL DETDRLEEGR KLIQIAITKL LQSRIMASYH 120
  121 EKQADNNRLK LLQELEEEKR KKREKEEKKQ KKREKEKEKK RLQQLAKEEE KRKREEEKER 180
  181 LKKELEEREM RRREAQRKKV EEAKRKKDEE RKRRLEEQQR REEMQEKQRK QKEELKRKRE 240
  241 EEKKRIREQK RLEQEKLQKE KEEEERQRLI AEDALRKQKL 

[Run NCBI BLAST on this sequence.]

Detection Method: MSA

Shown below is our most confident prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #4
Region A:
Residues: [777-1093]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 NEEQTSANIL SAKPFTENGV GNPVSSQSHP NMTNYQEDNS CSINDEILKM VNSVAASKPV  60
   61 SPTGFNVHDL LLPSTNNQMP AMEQSHLPQP GNQNNHFGTT TIPNALDLAT KSSLQTENNY 120
  121 LMNSQTLENT SLLMHNNSSP TKLLPNDFGL SSWGGLTNTM SINPTCKPPV IQTSEMESQA 180
  181 HKSSPQATMP SFGLPNGGTH RKSFTDELNT LTSMLSSSGF ADTSLSSSGF PPSQRSVWND 240
  241 QKSSFSGPST AGNFNNSSIQ SGMLLAPTLG SVESFPNRTS IWDSSTTPMM NKSELSGRNI 300
  301 TSTAQDSPAF MASNIWS

[Run NCBI BLAST on this sequence.]

Detection Method: ORFEUS
Confidence: 9.82
Match: 1ldvA
Description: No description for 1ldvA was found.

Predicted Domain #5
Region A:
Residues: [1094-1240]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 SNSQYNSPYL TSNVLQSPQI SSGVDESHIL DSIYNTYLAI SPQDSLNPYI AIGTLFQNLV  60
   61 GLNLDYSTFI NKLISMQGAY NCEFFTDNNG SITHVRFARQ TPAGHSKGLL NQLFSGLNDP 120
  121 TATPFTSRPH TSTRASFPIA SSTTQTS

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.


YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle