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View Structure Prediction Details

Protein: YDJ1
Organism: Saccharomyces cerevisiae
Length: 409 amino acids
Reference: Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for YDJ1.

Description E-value Query
Range		 Subject
Range
YDJ1 - Protein chaperone involved in regulation of the HSP90 and HSP70 functions; involved in protein trans...
MAS5_YEAST - Mitochondrial protein import protein MAS5 OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) G...
 0.0 [1..409] [1..409]
gi|4210948 - gi|4210948|gb|AAD12055.1| DnaJ protein [Hevea brasiliensis]
 0.0 [2..409] [9..415]
gi|4008159 - gi|4008159|dbj|BAA35121.1| DnaJ homolog [Salix gilgiana]
 0.0 [2..409] [9..420]
gi|10945671, gi|... - gi|10945671|gb|AAG24643.1|AF308738_1 J2P [Daucus carota], gi|10945669|gb|AAG24642.1|AF308737_1 J1P [...
 0.0 [2..409] [9..418]
gi|7507776 - gi|7507776|pir||T16867 probable cytochrome P450 T13C5.1 [similarity] - Caenorhabditis elegans
 0.0 [2..409] [9..419]
DNJH_CUCSA - DnaJ protein homolog OS=Cucumis sativus GN=DNAJ1 PE=2 SV=1
 0.0 [2..409] [8..413]
gi|6782421 - gi|6782421|gb|AAF28382.1|AF124139_1 DnaJ-like protein [Lycopersicon esculentum]
 0.0 [2..409] [9..419]
DNAJ_GEOTM - Chaperone protein DnaJ OS=Geobacillus thermoglucosidasius GN=dnaJ PE=3 SV=1
 0.0 [2..378] [1..379]
DNJA4_MOUSE - DnaJ homolog subfamily A member 4 OS=Mus musculus GN=Dnaja4 PE=1 SV=1
 0.0 [1..407] [1..395]

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Predicted Domain #1
Region A:
Residues: [1-112] 
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MVKETKFYDI LGVPVTATDV EIKKAYRKCA LKYHPDKNPS EEAAEKFKEA SAAYEILSDP  60
   61 EKRDIYDQFG EDGLSGAGGA GGFPGGGFGF GDDIFSQFFG AGGAQRPRGP QR

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 193.228787
Match: 1hdj__
Description: HSP40
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
unfolded protein binding 3.04403163860617 bayes_pls_golite062009
chaperone binding 2.86745334638583 bayes_pls_golite062009
protein binding 2.65982681685488 bayes_pls_golite062009
binding 2.63138872417193 bayes_pls_golite062009
heat shock protein binding 2.17994194200939 bayes_pls_golite062009
transcription regulator activity 1.91297632253219 bayes_pls_golite062009
nucleic acid binding 1.6342534817623 bayes_pls_golite062009
DNA binding 1.55234338199368 bayes_pls_golite062009
Hsp70 protein binding 0.541755903922701 bayes_pls_golite062009
transferase activity 0.240656521918556 bayes_pls_golite062009
catalytic activity 0.106988907594358 bayes_pls_golite062009
receptor binding 0.0658139321670459 bayes_pls_golite062009
phosphotransferase activity, alcohol group as acceptor 0.0276971914937192 bayes_pls_golite062009

Predicted Domain #2
Region A:
Residues: [113-196] 
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 GKDIKHEISA SLEELYKGRT AKLALNKQIL CKECEGRGGK KGAVKKCTSC NGQGIKFVTR  60
   61 QMGPMIQRFQ TECDVCHGTG DIID

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 18.0
Match: 1exkA_
Description: Cysteine-rich domain of the chaperone protein DnaJ.
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
binding 2.7298921704023 bayes_pls_golite062009
protein binding 2.6297172985864 bayes_pls_golite062009
protein disulfide isomerase activity 2.4409950647303 bayes_pls_golite062009
intramolecular oxidoreductase activity, transposing S-S bonds 2.4409950647303 bayes_pls_golite062009
intramolecular oxidoreductase activity, interconverting keto- and enol-groups 2.23398279564144 bayes_pls_golite062009
unfolded protein binding 2.04158808514315 bayes_pls_golite062009
receptor binding 1.01508461105961 bayes_pls_golite062009
catalytic activity 0.276917867171685 bayes_pls_golite062009

Predicted Domain #3
Region A:
Residues: [197-255] 
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 PKDRCKSCNG KKVENERKIL EVHVEPGMKD GQRIVFKGEA DQAPDVIPGD VVFIVSERP

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 146.315398
Match: 1c3gA_
Description: Heat shock protein 40 Sis1
Matching Structure (courtesy of the PDB):

Predicted Domain #4
Region A:
Residues: [256-409] 
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 HKSFKRDGDD LVYEAEIDLL TAIAGGEFAL EHVSGDWLKV GIVPGEVIAP GMRKVIEGKG  60
   61 MPIPKYGGYG NLIIKFTIKF PENHFTSEEN LKKLEEILPP RIVPAIPKKA TVDECVLADF 120
  121 DPAKYNRTRA SRGGANYDSD EEEQGGEGVQ CASQ

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 146.315398
Match: 1c3gA_
Description: Heat shock protein 40 Sis1
Matching Structure (courtesy of the PDB):
YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle