YRC Public Data Repository - Protein Structure Prediction

Protein:	VAC7
Organism:	Saccharomyces cerevisiae
Length:	1165 amino acids
Reference:	Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for VAC7.

Description	E-value	Query Range	Subject Range
VAC7_YEAST - Vacuolar segregation protein 7 OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=VAC7 PE=1... VAC7 - Integral vacuolar membrane protein involved in vacuole inheritance and morphology; activates Fab1p k...	0.0	[1..1165]	[1..1165]
gi\|25496719 - pir\|\|B97033 uncharacterized protein, related to enterotoxins of other Clostridiales [imported] - Clo... gi\|15894364, gi\|... - gi\|15894364\|ref\|NP_347713.1\| hypothetical protein CAC1079 [Clostridium acetobutylicum ATCC 824], gi\|...	7.0E-8	[147..398]	[2..252]
GERIA_BACCE - Spore germination protein GerIA OS=Bacillus cereus GN=gerIA PE=3 SV=1 gi\|229193019, gi... - gi\|229193019\|ref\|ZP_04319975.1\| Spore germination protein gerIA [Bacillus cereus ATCC 10876], gi\|228...	1.0E-4	[338..486]	[9..152]
gi\|7507776 - gi\|7507776\|pir\|\|T16867 probable cytochrome P450 T13C5.1 [similarity] - Caenorhabditis elegans	0.001	[261..651]	[1235..1617]
gi\|6562743, gi\|1... - gi\|6562743\|emb\|CAB62882.1\| GTPase of unknown function, putative [Plasmodium falciparum 3D7], gi\|2351...	0.006	[304..421]	[91..200]
gi\|156980959, gi... - gi\|156980959\|ref\|YP_001443218.1\| N-acetylmuramoyl-L-alanine amidase [Staphylococcus aureus subsp. au... gi\|25506904 - pir\|\|D90072 hypothetical protein SA2437 [imported] - Staphylococcus aureus (strain N315) gi\|255007416 - gi\|255007416\|ref\|ZP_05146017.2\| N-acetylmuramoyl-L-alanine amidase [Staphylococcus aureus subsp. aur... gi\|90428972, gi\|... - gi\|90581976\|ref\|ZP_01237741.1\| Mannosyl-glycoprotein endo-beta-N-acetylglucosamidase:CHAP [Staphyloc... gi\|253316648 - gi\|253316648\|ref\|ZP_04839861.1\| N-acetylmuramoyl-L-alanine amidase [Staphylococcus aureus subsp. aur... gi\|90431747, gi\|... - gi\|90584690\|ref\|ZP_01240403.1\| Mannosyl-glycoprotein endo-beta-N-acetylglucosamidase:CHAP [Staphyloc... gi\|15925634, gi\|... - gi\|15925634\|ref\|NP_373168.1\| N-acetylmuramoyl-L-alanine amidase [Staphylococcus aureus subsp. aureus... gi\|15928230, gi\|... - gi\|15928230\|ref\|NP_375763.1\| N-acetylmuramoyl-L-alanine amidase [Staphylococcus aureus subsp. aureus... gi\|269204281\|ref... - N-acetylmuramoyl-L-alanine amidase [Staphylococcus aureus subsp. aureus ED98]	0.006	[272..595]	[28..365]
gi\|15829164 - gi\|15829164\|ref\|NP_326524.1\| membrane nuclease, lipoprotein [Mycoplasma pulmonis UAB CTIP] gi\|14090108, gi\|... - pir\|\|E90598 membrane nuclease, lipoprotein [imported] - Mycoplasma pulmonis (strain UAB CTIP), gi\|14...	0.007	[270..482]	[488..691]

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Predicted Domain #1

Region A:
Residues: [1-260]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MTEEDRKLTV ETETVEAPVA NNLLLSNNSN VVAPNPSIPS ASTSTSPLHR EIVDDSVATA  60
   61 NTTSNVVQHN LPTIDNNLMD SDATSHNQDH WHSDINRAGT SMSTSDIPTD LHLEHIGSVS 120
  121 STNNNSNNAL INHNPLSSHL SNPSSSLRNK KSSLLVASNP AFASDVELSK KKPAVISNNM 180
  181 PTSNIALYQT ARSANIHGPS STSASKAFRK ASAFSNNTAP STSNNIGSNT PPAPLLPLPS 240
  241 LSQQNKPKII ERPTMHVTNS

[Run NCBI BLAST on this sequence.]

Detection Method:

deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #2

Region A:
Residues: [261-720]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 REILLGENLL DDTKAKNAPA NSTTHDNGPV ANDGLRIPNH SNADDNENNN KMKKNKNINS  60
   61 GKNERNDDTS KICTTSTKTA PSTAPLGSTD NTQALTASVS SSNADNHNNN KKKTSSNNNG 120
  121 NNSNSASNKT NADIKNSNAD LSASTSNNNA INDDSHESNS EKPTKADFFA ARLATAVGEN 180
  181 EISDSEETFV YESAANSTKN LIFPDSSSQQ QQQQQQPPKQ QQQQQNHGIT SKISAPLLNN 240
  241 NKKLLSRLKN SRHISTGAIL NNTIATISTN PNLNSNVMQN NNNLMSGHNH LDELSSIKQE 300
  301 PPHQLQQQQP PMDVQSVDSY TSDNPDSNVI AKSPDKRSSL VSLSKVSPHL LSSTSSNGNT 360
  361 ISCPNVATNS QELEPNNDIS TKKSLSNSTL RHSSANRNSN YGDNKRPLRT TVSKIFDSNP 420
  421 NGAPLRRYSG VPDHVNLEDY IEQPHNYPTM QNSVKKDEFY

[Run NCBI BLAST on this sequence.]

Detection Method:

MSA

Shown below is our most confident prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #3

Region A:
Residues: [721-1165]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 NSRNNKFPHG LNFYGDNNVI EEENNGDSSN VNRPQHTNLQ HEFIPEDNES DENDIHSMFY  60
   61 YNHKNDLETK PLISDYGEDE DVDDYDRPNA TFNSYYGSAS NTHELPLHGR MPSRSNNDYY 120
  121 DFMVGNNTGN NNQLNEYTPL RMKRGQRHLS RTNNSIMNGS IHMNGNDDVT HSNINNNDIV 180
  181 GYSPHNFYSR KSPFVKVKNF LYLAFVISSL LMTGFILGFL LATNKELQDV DVVVMDNVIS 240
  241 SSDELIFDIT VSAFNPGFFS ISVSQVDLDI FAKSSYLKCD SNGDCTVMEQ ERKILQITTN 300
  301 LSLVEESANN DISGGNIETV LLGTAKKLET PLKFQGGAFN RNYDVSVSSV KLLSPGSREA 360
  361 KHENDDDDDD DGDDGDDENN TNERQYKSKP NARDDKEDDT KKWKLLIKHD YELIVRGSMK 420
  421 YEVPFFNTQK STAIQKDSMV HPGKK

[Run NCBI BLAST on this sequence.]

Detection Method:

deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #4

Region A:
Residues: [758-905]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 NLQHEFIPED NESDENDIHS MFYYNHKNDL ETKPLISDYG EDEDVDDYDR PNATFNSYYG  60
   61 SASNTHELPL HGRMPSRSNN DYYDFMVGNN TGNNNQLNEY TPLRMKRGQR HLSRTNNSIM 120
  121 NGSIHMNGND DVTHSNINNN DIVGYSPH

[Run NCBI BLAST on this sequence.]

Detection Method:

deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #5

Region A:
Residues: [906-1165]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 NFYSRKSPFV KVKNFLYLAF VISSLLMTGF ILGFLLATNK ELQDVDVVVM DNVISSSDEL  60
   61 IFDITVSAFN PGFFSISVSQ VDLDIFAKSS YLKCDSNGDC TVMEQERKIL QITTNLSLVE 120
  121 ESANNDISGG NIETVLLGTA KKLETPLKFQ GGAFNRNYDV SVSSVKLLSP GSREAKHEND 180
  181 DDDDDDGDDG DDENNTNERQ YKSKPNARDD KEDDTKKWKL LIKHDYELIV RGSMKYEVPF 240
  241 FNTQKSTAIQ KDSMVHPGKK

[Run NCBI BLAST on this sequence.]

Detection Method:

deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits