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View Structure Prediction Details

Protein: COG6
Organism: Saccharomyces cerevisiae
Length: 839 amino acids
Reference: Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for COG6.

Description E-value Query
Range
Subject
Range
COG6 - Component of the conserved oligomeric Golgi complex (Cog1p through Cog8p), a cytosolic tethering com...
COG6_YEAST - Conserved oligomeric Golgi complex subunit 6 OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c...
0.0 [1..839] [1..839]
gi|6382012 - gi|6382012|dbj|BAA86448.1| KIAA1134 protein [Homo sapiens]
0.0 [131..749] [20..593]
COG6_MOUSE - Conserved oligomeric Golgi complex component 6 - Mus musculus (Mouse)
0.0 [161..749] [1..545]
cogc-6 - status:Partially_confirmed UniProt:Q21270 protein_id:AAA96179.1
0.0 [140..723] [12..528]
cog6 - Golgi transport complex peripheral subunit Cog6
COG6_SCHPO - Conserved oligomeric Golgi complex subunit 6 OS=Schizosaccharomyces pombe (strain 972 / ATCC 24843) ...
0.0 [139..627] [17..486]
CG1968-PA - This gene is referred to in FlyBase by the symbol Dmel\CG1968 (CG1968, FBgn0033401). It is a protein...
0.0 [142..674] [14..496]

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Predicted Domain #1
Region A:
Residues: [1-119]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MDFVVDYQTY AMADTATPEL PEPEPRLNLT SDAQSQPTGK LDLQFKLPDL QRYSNNNATL  60
   61 PVDNDGAGSK DLHKKMTHYA MSSIDKIQLS NPSKQLGQNS QDEKLSQQES QNFTNYEPK

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #2
Region A:
Residues: [120-511]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 NLDLSKLVSP SSGSNKNTTN LVLSNKLSKI LNNYTLINYQ ATVQLRKSLK VLEENKERLS  60
   61 LDEQKLMNPE YVGTLARRAL RTDLESQLLK EHITVLEEFK PIIRRIKRLS SSVEKIQRTS 120
  121 EKLLSNETNE VPTNNVVLQE IDQYRLKAEQ LKLKKKILLS IRDRFTLNQV EDDVITNGTI 180
  181 DNIFFEVVKK VINIKDESSF LLTLPNLNAG NALIMGVNEI LEKTNKKIFN YLIDFLYSFE 240
  241 SSSNLLNDHG TTEQESLNIF RKSLVFLSSD LELFNELLKR VTTLRSKSIL DEFLSQFDMN 300
  301 STTSKPIILS AHDPIRYIGD VLASVHSIIA NEADFVKSLF DFQDEDLKDT PISILQQNKT 360
  361 FLKGIDNKLL NDIIQSLSNS CRIRIEQIVR FE

[Run NCBI BLAST on this sequence.]

Detection Method: MSA

Shown below is our most confident prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #3
Region A:
Residues: [512-606]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 ENPIINFEIV RLLKLYRVMF ERKGIQDDSS IINNLKSLED ISKNRIIGYY EDYMKQTVMA  60
   61 ETKNSSDDLL PPEWLSEYMN KLVELFEIYE KTHAA

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

    MCM
Score
GO
Score
GO
Term
SCOP
Match
SCOP Description
View Download 0.876 0.010 intra-Golgi vesicle-mediated transport a.7.6 Ribosomal protein S20

Predicted Domain #4
Region A:
Residues: [607-839]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 EDEESEDNKL LSSKNLQTIV EQPIKDVLLK QLQTSFPLAK KNEKEKASLL TIEINCFDLI  60
   61 KSRLQPFEGL FAQDDDSRKI TIWVCDKLKE YTKQMLTLQI KFLFENTGLD LYSNLVNMIF 120
  121 PVDSVKDELD YDMYLALRDN SLMELDMVRK NVHDKLNYYL PQALTDVQGN LLFKLTSPMI 180
  181 ADEICDECFK KLSLFYNIFR KLLIHLYPNK KDQVFEILNF STDEFDMLIG IDH

[Run NCBI BLAST on this sequence.]

Detection Method: ORFEUS
Confidence: 9.12
Match: 1n1bA
Description: (+)-bornyl diphosphate synthase
Matching Structure (courtesy of the PDB):

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle