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View Structure Prediction Details

Protein: HEF3
Organism: Saccharomyces cerevisiae
Length: 1044 amino acids
Reference: Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for HEF3.

Description E-value Query
Range
Subject
Range
HEF3 - Translational elongation factor EF-3; paralog of YEF3 and member of the ABC superfamily; stimulates ...
EF3B_YEAST - Elongation factor 3B OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=HEF3 PE=1 SV=2
0.0 [1..1044] [1..1044]
gi|3786314 - gi|3786314|dbj|BAA33959.1| translation elongation factor3 [Candida glabrata]
0.0 [1..1044] [1..1045]
gi|7507776 - gi|7507776|pir||T16867 probable cytochrome P450 T13C5.1 [similarity] - Caenorhabditis elegans
0.0 [2..1044] [5..1050]
EF3_CANAL - Elongation factor 3 OS=Candida albicans GN=TEF3 PE=1 SV=1
0.0 [2..1044] [5..1049]
EF3_SCHPO - Elongation factor 3 OS=Schizosaccharomyces pombe (strain 972 / ATCC 24843) GN=tef3 PE=1 SV=1
tef3 - translation elongation factor eEF3
0.0 [2..1042] [5..1046]
EF3_PNECA - Elongation factor 3 OS=Pneumocystis carinii GN=TEF3 PE=3 SV=1
0.0 [1..1043] [1..1042]
gi|13442976 - gi|13442976|gb|AAK26245.1| elongation factor 3 [Cryptococcus neoformans var. neoformans]
gi|58266210, gi|... - gi|58266210|ref|XP_570261.1| elongation factor 3 [Cryptococcus neoformans var. neoformans JEC21], gi...
gi|134111046, gi... - gi|50258329|gb|EAL21018.1| hypothetical protein CNBD3940 [Cryptococcus neoformans var. neoformans B-...
0.0 [18..1042] [21..1054]

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Predicted Domain #1
Region A:
Residues: [1-321]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MSDSQQSITV LEELFRKLET ATSETREGIS SELSSFLNGN IIEHDVPEVF FDEFQKAIQS  60
   61 KQKALNTLGA VAYIANETNL SPSVEPYIVA TVPSVCSKAG SKDNDVQLAA TKALKAIASA 120
  121 VNPVAVKALL PHLIHSLETS NKWKEKVAVL EVISVLVDAA KEQIALRMPE LIPVLSESMW 180
  181 DTKKGVKEAA TTTITKATET VDNKDIERFI PKLIECIANP NEVPETVHLL GATTFVAEVT 240
  241 PATLSIMVPL LSRGLAERET SIKRKAAVII DNMCKLVEDP QVVAPFLGKL LPGLKNNFAT 300
  301 IADPEAREVT LKALKTLRRV G

[Run NCBI BLAST on this sequence.]

Detection Method: MSA

Shown below is our most confident prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #2
Region A:
Residues: [322-418]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 NVGEDDVLPE ISHAGDVSTT LGVIKELLEP EKVAPRFTIV VEYIAAIAAN LIDERIIDQQ  60
   61 TWFTHVTPYM TIFLHEKTAK EILDDFRKRA VDNIPVG

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

    MCM
Score
SCOP
Match
SCOP Description
View Download 0.942 a.27.1 Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases

Predicted Domain #3
Region A:
Residues: [419-645]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 PNFQDEEDEG EDLCNCEFSL AYGAKILLNK TQLRLKRGRR YGLCGPNGAG KSTLMRSIAN  60
   61 GQVDGFPTQD ECRTVYVEHD IDNTHSDMSV LDFVYSGNVG TKDVITSKLK EFGFSDEMIE 120
  121 MPIASLSGGW KMKLALARAV LKDADILLLD EPTNHLDTVN VEWLVNYLNT CGITSVIVSH 180
  181 DSGFLDKVCQ YIIHYEGLKL RKYKGNLSEF VQKCPTAQSY YELGASD

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 93.383689
Match: 1b0uA_
Description: ATP-binding subunit of the histidine permease
Matching Structure (courtesy of the PDB):

Predicted Domain #4
Region A:
Residues: [646-1044]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 LEFQFPTPGY LEGVKTKQKA IVKVSNMTFQ YPGTTKPQVS DVTFQCSLSS RIAVIGPNGA  60
   61 GKSTLINVLT GELLPTSGEV YTHENCRIAY IKQHAFAHIE SHLDKTPSEY IQWRFQTGED 120
  121 RETMDRANRQ INENDAEAMN KIFKIEGTPR RVAGIHSRRK FKNTYEYECS FLLGENIGMK 180
  181 SERWVPMMSV DNAWLPRGEL IESHSKMVAE IDMKEALASG QFRALTRKEI ELHCAMLGLD 240
  241 SELVSHSRIR GLSGGQKVKL VLAACTWQRP HLIVLDEPTN YLDRDSLGAL SKALKAFEGG 300
  301 VIIITHSAEF TKNLTDEVWA VKDGKMTPSG HNWVAGQGAG PRIEKKEEEG DKFDAMGNKI 360
  361 NSGKKKSKLS SAELRKKKKE RMKKKKEMGD EYVSSDEDF

[Run NCBI BLAST on this sequence.]

Detection Method: MSA

Shown below is our most confident prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.


YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle